Articles

Relationship of Alberta Stroke Program Early CT Score (ASPECTS) with the outcome of ischemic stroke and the neurocognitive stroke biomarkers

Reliable and acceptable biomarkers are needed to anticipate the outcome and cognitive impairment following ischemic stroke. The goal of this research is to examine the association of ASPECTS with cognitive dec...

Authors: Ahmed Esmael, Mohammed Elsherief, Ahmed Abdel Khalek Abdel Razek, Nehal Tharwat Mohammed El-Sayed, Mohammed Abd Elsalam, Mohamed E. Flifel and Saad Shawki

Copeptin: a potential blood biomarker for acute ischemic stroke

Copeptin is a new blood biomarker for acute ischemic stroke which emerged to assist clinicians with decision-making. Serum copeptin can accurately reflect vasopressin concentration, which plays a role in aggra...

Authors: Mohammed I. Oraby, Rasha H. Soliman, Rehab M. Abd Elkareem and Amna I. Mohammed

Depression among health workers caring for patients with COVID-19 in Egypt

Health care workers caring for patients with COVID-19 pandemic are prone to extraordinary stressors and psychological problems. The aim of this study was to estimate the prevalence and risk factors of major de...

Authors: Hayam Mohamed Elgohary, Mohammad Gamal Sehlo, Medhat Mohamed Bassiony, Usama Mahmoud Youssef, Dina Sameh Elrafey and Shimaa Ibrahim Amin

Intracerebral hemorrhage due to moyamoya syndrome as a rare presentation of cerebral rheumatoid vasculitis: a case report

Central nervous system affection in rheumatoid arthritis is rare. The most frequently encountered neurological complications with rheumatoid arthritis are peripheral neuropathy and atlantoaxial subluxation wit...

Authors: Ayman Hassan El-Sudany, Salah Hussein El-Halawany, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros, Mostafa Hashim Mostafa and Ahmed El-Bassiouny

High-resolution neuromuscular ultrasound-based diagnosis of carpal tunnel syndrome in a sample of Egyptian population

Carpal tunnel syndrome is the commonest entrapment neuropathy. The cut-off point of cross-sectional area to diagnose carpal tunnel syndrome may vary among populations. The objective of this study was to determ...

Authors: Ahmed ElSadek, Mai Fathy and Amr AbdElMoneim

Surgical management of chronic subdural hematomas through single-burr hole craniostomy: is it sufficient?

Symptomatic chronic subdural hematomas (CSDH) remain one of the most encountered forms of intracranial hemorrhages particularly in the elder patients, yet fortunately implies a good surgical prognosis. Burr ho...

Authors: Omar El Farouk Ahmed, Ahmad El Sawy and Shafik El Molla

Psychomotor function in children with epilepsy seen at a tertiary hospital in southern Nigeria: does treatment with anti-epileptic drugs have any effect?

Psychomotor slowing is more commonly reported in children with epilepsy (CWE) compared to healthy controls. The effect of anti-epileptic drug (AED) treatment on psychomotor abilities of CWE remains controversi...

Authors: Paul Ehiabhi Ikhurionan, Olusola Peter Okunola, Blessing Imuetinyan Abhulimhen-Iyoha and Gabriel Egberue Ofovwe

Signs of neuroinflammation outweigh neurodegeneration as predictors for early conversion to MS

The pathophysiological mechanisms underlying multiple sclerosis include both inflammatory and degenerative processes. We aimed to study and compare markers of neuroinflammation and neurodegeneration in patient...

Authors: Nervana Mohamed El Fayomy, Hanan Helmy Mohamed, Manal Mohamed Kamal, Aya Hamid Alsayyad, Enas Hamid Alsayyad and Reham Mohamed Shamloul

How COVID-19 pandemic changed our management strategies for amyotrophic lateral sclerosis (ALS) patients: Egyptian study

There are several studies that have discussed the efficacy of telemedicine with amyotrophic lateral sclerosis (ALS) patients; however, this approach is still preliminary in Egypt and in North Africa. The objec...

Authors: Hebatallah R. Rashed

Evaluation of platelets activity and reactivity as risk factors for acute ischemic non-embolic stroke in young adults

Ischemic stroke (IS) constitutes a relevant health concern recently in younger population causing permanent cognitive and function-limiting disability and ranks as the 3rd cause of death in Egypt after cardiac...

Authors: Hebat-Allah Hassan Nashaat, Alaa El-Din Saad Abdelhamid, Amal Sayed Ahmed, Ahmed Osama Hosny, Mohamed A. Saad, Mohammed El Samahy and Amany Moustafa Hassan

Sinus venous thrombosis as a complication of COVID-19-associated hypercoagulability

Sinus venous thrombosis (SVT) is an increasingly recognised complication of not only SARS-CoV-2 infections, but also of SARS-CoV-2 vaccinations. SVT is attributed to hypercoagulability, a common complication o...

Authors: Sinda Zarrouk and Josef Finsterer

Enhanced sensory conduction in primary fibromyalgia: a case–control pilot study

This study aimed to test the changes in the conduction properties of peripheral nerves in patients with primary fibromyalgia (FM). Thirty patients with FM and sixteen healthy controls participated in this stud...

Authors: Mohamed N. Thabit, Mostafa Abdelmomen, Esam Aboelfadl and Saber Hadad

Outcomes of pregnancy in Egyptian women with multiple sclerosis in the new treatment era: a multi-center retrospective observational study

Pregnancy is a recent growing issue in multiple sclerosis (MS) and the update in the diagnostic criteria of MS and introduction of many disease-modifying therapies (DMTs) may cause changes in the relationship ...

Authors: Ali Mahmoud Ahmed, Mohamed Al-Bahay M. G. Reda and Ahmed Hassan Elsheshiny

Assessment of carpal tunnel syndrome via ultrasonography among hospital workers: a screening study

Carpal tunnel syndrome is a reasonably common disorder among working individuals. It may also be a cause of functional impairment. The aim of the study was to screen for the presence of carpal tunnel syndrome ...

Authors: Mai Fathy, Ahmed ElSadek, Eman Hamid and Amr AbdElMoneim

Frequency and risk factors of carotid artery disease among ischemic stroke patients in the south Egypt: hospital-based study

Limited data are available on the frequency of carotid artery disease among cerebrovascular ischemic stroke (CVS) patients in south Egypt. The aim of the present study is to determine the prevalence and risk f...

Authors: Eman Khedr, Abeer A. Tony, Mohamed Habeel and Ahmed Nasreldein

Assessment of cognitive functions in patients with multiple sclerosis

About 40–70% of patients with multiple sclerosis (MS) develop cognitive impairment (CI) throughout their life. We aim to study the influence of MS on cognitive changes. This is a case–control study of fifty pa...

Authors: Tara A. Al-Falaki, Farqad B. Hamdan and Nawfal M. Sheaheed

Epidemiological profile of brain tumors in Cameroon: a retrospective study

Brain tumors represent group of neoplasms originating from intracranial tissues and the meninges. The aim of this study was to determine the epidemiological profile of brain tumors seen in a referral health ce...

Authors: Mathieu Motah, Daniel Gams Massi, Fabien Fouda Bekolo, Nkemontoh Akweseh Nju, Aurélien Ndoumbe, Mireille Moumi, Anne Sango, Paul Shu and Victor Eyenga

High leukotriene B4 serum levels increase risk of painful diabetic neuropathy among type 2 diabetes mellitus patients

Painful diabetic neuropathy is one of the most common complications of type 2 diabetes mellitus, with approximately 30–50% of people will experience diabetic neuropathy. Chronic hyperglycemia will cause an inf...

Authors: Kelvin Yuwanda, I Putu Eka Widyadharma, Dewa Putu Gde Purwa Samatra, I Made Oka Adnyana, Anna Marita Gelgel and I Komang Arimbawa

Electrophysiological characteristics and anatomical differentiation of epileptic and non-epileptic myoclonus

Electrophysiological techniques have been used for discriminating myoclonus from other hyperkinetic movement disorders and for classifying the myoclonus subtype. This study was carried out on patients with dif...

Authors: Mohammad Abu-Hegazy, Azza Elmoungi, Eman Eltantawi and Ahmed Esmael

A study of anxiety, depression and stress symptoms among Fayoum medical students during COVID-19 lockdown, Egypt

The widespread pandemic of COVID-19 virus carries not only physical hazards, but also major psychological effects especially among medical students. The aim was to investigate the psychological effects of COVI...

Authors: Mohamed R. Soltan, Shaimaa S. Soliman and Mariam E. Dawoud

Neurological sequelae of COVID-19: a review

The COVID-19 pandemic has produced a myriad of challenges, including identifying and treating neurological sequelae.

Authors: Christopher J. Peterson, Ashish Sarangi and Fariha Bangash

Reply to Letter to Editor: Is SARS-CoV-2 responsible for relapses of Parkinson’s disease?

Authors: Walaa A. Kamel, Ismail Ibrahim Ismail, Mohamed Ibrahim and Jasem Y. Al-Hashel

Pathophysiology of SARS-CoV-2-associated ischemic stroke is variegated

Authors: Fulvio A. Scorza, Ana C. Fiorini and Josef Finsterer

Cognitive impairment and depression in patients with relapsing–remitting multiple sclerosis depending on age and neuroimaging findings

Multiple sclerosis is an insidious, disabling, both physically and mentally, demyelinating disease of the central nervous system. This work aims to evaluate relationships between cognitive impairment in separa...

Authors: Oksana O. Kopchak and Tetiana A. Odintsova

Dilemma of migraine diagnosis and management among non-neurologists

Migraine is a common and debilitating disorder however there is a wide gap in its diagnosis and management. Many migraine patients present to non-neurologists, so it is of utmost importance that non neurologis...

Authors: Mai Fathy, Ahmed ElSadek, Sherien Farag, Shahinaz Helmy and Amr AbdElMoneim

Impact of vitamin D level in diabetic people with peripheral neuropathy

Diabetes mellitus (DM) is a metabolic disease which is complicated by occurrence of diabetic peripheral neuropathy (DPN). Vitamin D deficiency contributes to the etiology and progression of type 2 DM and devel...

Authors: Mohammad H. Assy, Nashwa A. Draz, Sabah E. Fathy and Mohammad G. Hamed

A volumetric magnetic resonance imaging study in migraine

Although migraine phenotype has been widely described, the explanation of migraine pathophysiology still has a gap that might be partly bridged by neuroimaging investigations. The aim of the study is to assess...

Authors: Laila Elmously Naguib, Ghada Saed Abdel Azim and Mohammed Abdelrazek Abdellatif

Impact of body mass index on duplex parameters of cranial vessels among the Egyptian population

Obesity is a major health problem that affects different vascular systems, including cerebrovascular circulation. Carotid duplex is the best screening tool for early diagnosis of cerebrovascular changes in rel...

Authors: Tarek A. Rageh, Mostafa Ghazally and Khaled O. Mohamed

Serum levels of leptin and adiponectin in patients with multiple sclerosis

The role of adipokines such as leptin and adiponectin in regulating the immunity has been documented, however data concerning their consequence on multiple sclerosis (MS) Egyptian patients are deficient. The a...

Authors: Rasha M. Fahmi, Amr E. Kamel, Dorreya A. Elsayed, Amal A. Zidan and Noha T. Sarhan

Neurological manifestations of COVID-19 infection: an umbrella review

Neurological involvements of COVID-19 are one of the most reported manifestations of this infection. This study aims to systematically review the previous systematic reviews which addressed the neurological ma...

Authors: Samad Shams Vahdati, Alireza Ala, Dara Rahmanpour, Elyar Sadeghi-Hokmabadi and Fateme Tahmasbi

Giant intracavernous aneurysm presenting with isolated trigeminal neuralgia: a case report

Trigeminal neuralgia (TN) commonly affects individuals aged more than 50 years and is mostly primary owing to trigeminal nerve neurovascular compression. We report a case of secondary TN attributed to a giant ...

Authors: Fadhilah Hani Ishak, Abdul Hanif Khan Yusof Khan, Mohd Naim Mohd Yaakob, Mohd Fandi Al Khafiz Kamis, Anna Misyail Abdul Rashid, Wei Chao Loh, Janudin Baharin, Azliza Ibrahim, Liyana Najwa Inche Mat, Wan Aliaa Wan Sulaiman, Fan Kee Hoo and Hamidon Basri

Paradoxical role of hepatocyte growth factor in ischemic stroke: stroke risk/stroke recovery

Hepatocyte growth factor (HGF) has an obvious pathological role in atherosclerosis and plaque instability leading to an acute ischemic stroke; however, its beneficial role in stroke recovery is still restricte...

Authors: Ibraheim Al-Ahmar, Noha Mohamed and Hosna Elshony

Does type and number of used substances affect the severity of illness in patients with substance use disorders?

Substance use disorders (SUD) are considered as serious mental illnesses, with variability of age of onset, duration of illness, and type of used substance among patients. The effect of type and number of subs...

Authors: Maha Ali Hassan, Mohamed Ayman Abdelhameed, Mostafa Mahmoud Abd El-Naem and Mohamed Helmy Abdelhafeez

Neurological manifestations in mild and moderate cases of COVID-19

The coronavirus disease due to SARS COVID-2 emerged from Wuhan city in China in December 2019 and rapidly spread to more than 200 countries all over the world as a global health pandemic. Its primary presentat...

Authors: Ghada Saed Abdel Azim and Marwa Abdellah Osman

Role of contrast-enhanced FLAIR MRI in diagnosis of intracranial lesions

MR imaging plays a significant role in detection and characterization of different brain diseases. The role of the post-contrast T1-weighted image magnetic resonance imaging (T1W MRI) sequence has been widely ...

Authors: Wessam Mustafa, Sherif Ali, Nadia Elgendy, Samer Salama, Lamiaa El Sorogy and Mohamed Mohsen

Case report on Cotard’s syndrome (CS) in a patient with schizophrenia: a rare case from Malaysia

Cotard’s syndrome (CS) is a neuropsychiatric condition marked by nihilistic delusional(s). Due to its rarity, misdiagnosis of the syndrome often occurs. The current case study is of a Malaysian woman who was m...

Authors: Natasha Subhas, Khin Ohnmar Naing, Chaw Su, Jiann Lin Loo, Aishah Farhana Shahbudin, Vevehkanandar Sivasubramaniam and Reenisha Thyagarajan

Assessment of anxiety and depression among hospitalized COVID-19 patients in Thailand during the first wave of the pandemic: a cross-sectional study

Anxiety and depression in hospitalized COVID-19 patients in Thailand during the first wave of the pandemic were investigated. Thai version of Hospital Anxiety and Depression Scale (HADS) was chosen as an instr...

Authors: Wajana Thaweerat, Wannarat Amornnimit Pongpirul and Wisit Prasithsirikul

Exploring the factors associated with coronaphobia among physicians during the COVID-19 outbreak in Egypt

Coronaphobia refers to intensified and persistent fears of contracting COVID-19 virus infection. This study aimed to evaluate the newly termed phenomenon, coronaphobia, and address its associated correlates am...

Authors: Mohamed Abdelghani, Mervat S. Hassan, Hayam M. Elgohary and Eman Fouad

Knowledge, attitudes, and impact of COVID-19 pandemic among neurology patients in Jordan: a cross-sectional study

The impacts of the COVID-19 pandemic on health services offered to patients with non-communicable diseases, including chronic neurological illnesses, are diverse and universal. We used a self-reported question...

Authors: Mohammad Athamneh, Qais Sa’di, Belal Aldabbour, Yousef Khader and Waleed Batayha

Predictors of parenting stress in parents of children diagnosed with autism spectrum disorder: a scoping review

Identifying the predictors of parenting stress in parents of children with autism spectrum disorder is crucial to provide the best health-care services.

Authors: Haytham Mohammad Al-Oran and Lee Khuan

Vitamin D receptor gene polymorphisms and idiopathic Parkinson disease: an Egyptian study

Accumulating data have suggested that vitamin D receptor (VDR) gene is a pretender gene for vulnerability to Parkinson disease (PD). This study aimed to assess the relationship of VDR gene polymorphisms (FokI ...

Authors: Ebtesam Mohamed Fahmy, Mohamed Elsayed Elawady, Sahar Sharaf, Sarah Heneidy and Rania Shehata Ismail

Trigeminal nerve stimulation: a recently approved treatment approach in attention deficit hyperactivity disorder

Attention-deficit hyperactivity disorder (ADHD) with its high prevalence is a growing area of concern and research, whereas exact underlying pathophysiology remains unknown. Behavioral therapy and multiple med...

Authors: Mazlum Çöpür and Sidar Çöpür

A case series of post COVID-19 mucormycosis—a neurological prospective

Direct neurological manifestations of coronavirus disease whether peripheral or central are reported worldwide. Yet, along the 3rd wave of the pandemic especially in India, an associated angioinvasive opportun...

Authors: Tamer Roushdy and Eman Hamid

Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India

Temporal lobe epilepsy is the most common type of focal onset seizure. Focal onset seizure with impaired awareness, previously known as complex partial seizure (CPS), account for 18–40% of all seizure types. H...

Authors: Aleena Elizabeth Andrews, Naufal Perumpalath, Juvaina Puthiyakam and Andrews Mekkattukunnel

Retractorless brain surgery: technical considerations

Retraction is necessary to access deep areas in the brain and skull base, but prolonged and forceful use of fixed retraction might be injurious. Several techniques were developed, in the concept of minimally i...

Authors: Wael Mohamed Nazim and Mohamed Abdelrahman Elborady

A comparison of cognitive performances between neuromyelitis optica spectrum disorder and multiple sclerosis patients in Indian context

To compare the frequency and pattern of cognitive impairment in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) patients.

Authors: Swati Kumar, Goutam Gangopadhyay, Atanu Biswas, Souvik Dubey, Alak Pandit, Shambaditya Das and Biman Kanti Ray

Brain tumor surgery in the elderly: a single institution experience of short-term outcome—a retrospective case study

There is an evolving concern in the management of brain tumors in the elderly. The number of elderly people (aged 65 years or more) increases progressively, and there is a considerable percent of brain tumors ...

Authors: Mostafa F. Tantawy and Wael M. Nazim

Etiological profile of new-onset seizures among adult Egyptians

New-onset seizure (NOS) is defined as the first seizure within a 24-h period ever experienced by the patient. A first-ever seizure can be the first manifestation of epilepsy. Or it may be a symptom of a brain ...

Authors: Mahmoud Hemeida Mahmoud, Eman Mahmoud Awad, Ahmed Khalil Mohamed and Mohamed Ahmed Shafik

The role of appendectomy in the development of Parkinson’s disease: a retrospective study in a teaching hospital in Jordan

Parkinson’s disease is a degenerative brain disease related to the accumulation of an abnormally aggregated alpha-synuclein protein. A hypothesis was presumed that this protein will be transported retrogradely...

Authors: Said Salah Dahbour, Aseel Subuh, Rama Haddad, Tulay Al-Samardali and Aladdin Dahbour

Endocan serum levels in patients with low- and high-grade meningiomas: does this biomarker have an indicative role?

Meningiomas are one of the most common tumors of the brain and central nervous system. The key role of endocan in predicting tumor growth and prognosis has been shown for several types of cancers; however, thi...

Authors: Mohammad Javad Fattahi, Fatemeh Sedaghat, Mahyar Malekzadeh, Amir Ali Nejat, Maryam Poostkar, Yousef Saberi, Mousa Taghipour and Abbas Ghaderi