Articles

Screening of non-restorative sleep by quantitative EEG

Non-restorative sleep is the major cause of excessive daytime sleepiness and causes injures of the central nervous system. The most common cause of Excessive day sleepiness in a clinical setting is obstructive sl...

Authors: Leqaa El-Mekkawy, Dina El Salmawy, Mye A. Basheer, Eman Maher and Mona M. Nada

Quality of life of cardiac outpatients with and without psychiatric disorders: a cross-sectional study

The study aims to measure the quality of life (QOL) for cardiac outpatients with psychiatric disorders (CPP) in comparison to cardiac outpatients without psychiatric disorders (CPOP). A semi-structured intervi...

Authors: Ahmad Alzahrani, Abdullah Alqahtani, Abeer Saleh, Maryam Aloqalaa, Abdulaziz Abdulmajeed, Asrar Nadhrah and Nada Alhazmi

Baseline predictors of progression of Parkinson’s disease in a sample of Egyptian patients: clinical and biochemical

Clinical progression of Parkinson’s disease (PD) is highly heterogeneous, and its predictors are generally lacking. Identifying predictors of early disease progression is important for patients’ management and...

Authors: Asmaa Helmy, Eman Hamid, Mohamed Salama, Ahmed Gaber, Mahmoud El-Belkimy and Ali Shalash

Venous and arterial cerebral thrombosis: a COVID-19 dual pathology and single possible etiology—a case report

Corona virus disease of the year 2019 (COVID-19) is still devastating the world for more than 19 months since its declaration as a pandemic by world health organization. Its manifestations does not stand at re...

Authors: Tamer Roushdy and Nouran K. Sharaf

The sociodemographic and clinical profile of children with an autism spectrum disorder in the oriental region of Morocco

The objective of our study is to assess the clinical profile of autistic children in Morocco and the cultural perception of their parents. We collect data with a standard questionnaire on 130 children with aut...

Authors: Bouchra Oneib, Younes Fajoui and Fatima El Ghazouani

COVID-19, neurovascular thrombotic problem and short summary on blood coagulation disorder: a brief review

COVID-19 is the present global public health problem. This respiratory viral infection can manifest atypical presentation including neurological presentations. An important neurological problem in COVID-19 is ...

Authors: Rujittika Mungmunpuntipantip and Viroj Wiwanitkit

Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience

Coronavirus disease 2019 (COVID-19) not only caused a large surge of respiratory infections, it also had a potential association with and increases the risk of stroke. The pandemic has certainly provided new c...

Authors: Ahmad Sulaiman Alwahdy, Ika Yulieta Margaretha, Kenyo Sembodro Pramesti, Nailaufar Hamro, Viska Yuzella, Fitriani Nasution and Arfan Mappalilu

Prevalence and clinical implication of adverse childhood experiences and their association with substance use disorder among patients with schizophrenia

Adverse childhood experiences (ACEs) and substance use disorder (SUD) are well-known risk factors for psychosis and dramatically affect schizophrenia. In this research, we aimed to measure the prevalence of ad...

Authors: Amira Mohamed Yousef, Amany Elshabrawy Mohamed, Seham Mahmoud Eldeeb and Rehab S. Mahdy

Dissociative disorder in Mayer Rokitansky Küster Hauser syndrome with pulmonary agenesis: a case report

The Mayer Rokitansky Küster Hauser (MRKH) syndrome is a rare congenital disorder characterized by the absence of uterus and vagina in a patient who is phenotypically a female, with 46 XX karyotypes. It affects...

Authors: Sulochana Joshi, Anup Raj Bhandari, Prashant Shrestha and Rabi Shakya

Subclinical thyroid dysfunction and autoantibodies in acute ischemic and hemorrhagic stroke patients: relation to long term stroke outcome

Data regarding the relation between both subclinical thyroid dysfunction, thyroid autoantibodies and clinical outcomes in stroke patients are limited. This study aimed to evaluate subclinical thyroid dysfuncti...

Authors: Rania S. Nageeb, Amr M. Azmy, Heba F. Tantawy, Ghada S. Nageeb and Alaa A. Omran

Association between blood coagulability and migraine

An association between migraine and stroke has been suggested for a long period, although conclusive evidence has not been reported. Several theories about hypercoagulability have been proposed for the associa...

Authors: Ebtesam Mohamed Fahmy, Mona Salah Eldin Hamdy, Reem Medhat Mahmoud and Haidy Elshebawy

Post-SARS-CoV-2 vaccination venous sinus thrombosis: a literature review of 308 cases

There is accumulating evidence that SARS-CoV-2 vaccinations can be complicated by venous sinus thrombosis (VST). This review aimed at summarising and discussing previous and recent advances regarding the diagn...

Authors: Josef Finsterer and Sinda Zarrouk

Characteristics of COVID and post COVID polyneuropathies in adults and pediatrics: an Egyptian sample

The aim of this study is to describe the different forms of polyneuropathy associated with coronavirus disease 2019 (COVID-19) as a secondary neurological complication for (COVID-19) and the outcome from differen...

Authors: Haidy Elshebawy, Mohamed Y. Ezzeldin and Eman Hassan Elzamarany

Psychological factors affecting COVID-19 vaccine acceptance in Indonesia

Increasing the rate of vaccination is crucial in combating the COVID-19 pandemic. However, a survey of 112,888 Indonesians found that only 64.8% Indonesians were willing to be vaccinated, with 7.6% refusing al...

Authors: Theo Audi Yanto, Gilbert Sterling Octavius, Rivaldo Steven Heriyanto, Catherine Ienawi, Haviza Nisa and H. Emildan Pasai

A demographic profile of cervical injury: an Indonesian single tertiary hospital study with 6 months to 1-year follow-up

Spinal cord injury (SCI) can cause considerable morbidity and mortality. Until now there is no spinal cord injury profile in Indonesia. Therefore, this study aims to provide an overview of the spinal cord inju...

Authors: Lukas Widhiyanto, Aliefio Japamadisaw and Kukuh Dwiputra Hernugrahanto

Role of imaging in early diagnosis of acute ischemic stroke: a literature review

Stroke is a serious health condition that is responsible for more than 5% of total deaths. Near 20% of patients experiencing stroke die every year, resulting in the stroke being at the top of the list of preve...

Authors: Mohammad Amin Akbarzadeh, Sarvin Sanaie, Mahshid Kuchaki Rafsanjani and Mohammad-Salar Hosseini

The impact of clinical scales in Parkinson’s disease: a systematic review

Parkinson’s disease is one of the non-curable diseases and occurs by the prominent loss of neurotransmitter (dopamine) in substantia nigra pars compacta (SNpc). The main cause behind this is not yet identified...

Authors: Nikita Aggarwal, Barjinder Singh Saini and Savita Gupta

Eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome) imitating Guillain–Barre syndrome (GBS): a case report

Eosinophilic granulomatosis with polyangiitis (EGPA) is associated with vasculitic neuropathy and being rare can present as subacute symmetric sensorimotor quadriparesis mimicking Guillain–Barre syndrome (GBS)...

Authors: Dinesh Khandelwal, Mridula Singh, Ruchi Jagota and Vaibhav Mathur

Sleep in post-COVID-19 recovery period and its impact on different domains of quality of life

COVID-19 pandemic became a global health problem affecting the life of millions of people all over the world. The effects of this pandemic were not only on the physical and medical aspects but also on the psyc...

Authors: Samir El Sayed, Sarah Gomaa, Doaa Shokry, Ahmed Kabil and Ahmed Eissa

Adequate antibody response to BioNTech COVID vaccine in a multiple sclerosis patient treated with siponimod

Authors: Gulnaz Siddiqui, Heidi Maloni and Victor E. Nava

The possible relation between stigma, parent psychiatric symptoms, quality of life and the disease burden in families of children with autism spectrum disorder in Egypt: a multicentre study

Most autism spectrum disorder (ASD) interventions evaluated child outcomes and ignoring the role of parent and family factors on both the immediate- and long-term effects of therapy. The purpose of this study ...

Authors: Romany H. Gabra, Doaa F. Hashem and Gellan K. Ahmed

Severity-dependent variations of the neutrophil to lymphocyte ratio (NLR) in peripheral vestibular vertigo

Peripheral vestibular vertigo is a common cause of vertigo especially in the elderly. The neutrophil to lymphocyte ratio (NLR) is a rapid and cost-effective inflammatory marker that has been assessed previousl...

Authors: Andi Kurnia Bintang and Eva Iin Magasingan

Association between schizophrenia and periodontal disease in relation to cortisol levels: an ELISA-based descriptive analysis

Schizophrenia is a chronic psychosis marked by multiple bioenvironmental and immunological dysregulation with its intricate role in etiopathogenesis of periodontal disease remaining unclear. Hence, the aim of ...

Authors: Bariah Fahad Albahli, Najd Mohammed Alrasheed, Raghad Saleh Alabdulrazaq, Dhafer S. Alasmari and Muzammil Moin Ahmed

Multidisciplinary management of juvenile nasopharyngeal angiofibroma

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign, but the locally aggressive, vascular tumor that occurs almost exclusively in young men. Although this tumor accounts for only about 0.5% of head and...

Authors: Walid Abouzeid, Ahmed Sultan and Mohamed Shadad

Impact of COVID-19 pandemic in natural course of Moyamoya Angiopathy: an experience from tertiary-care-center in India

COVID-19 mediated immune dysregulation and cytokine storm can precipitate and aggravate Moyamoya angiopathy (MMA), influencing its disease course. This index study was undertaken to prospectively evaluate the ...

Authors: Shambaditya Das, Biman Kanti Ray, Ritwik Ghosh, Samya Sengupta, Alak Pandit and Souvik Dubey

Interictal autonomic dysfunction in patients with epilepsy

Autonomic nervous system (ANS) symptoms are frequently present in people with epilepsy (PwE). They are generally more prominent when they originate from the temporal lobe. We aim to investigate the alterations...

Authors: Kanar K. Shaker, Akram M. Al Mahdawi and Farqad B. Hamdan

Helicobacter pylori antibodies and multiple sclerosis: a single-center study and a short review of the literature

Multiple sclerosis is an immune-mediated disease which has been associated to a great variety of mechanisms that could influence its pathogenesis. Numerous reports in the medical literature suggest that Helicobac...

Authors: Yahveth Cantero-Fortiz, Iván Murrieta-Álvarez, Andrés Aurelio León-Peña, Miguel Antonio López-Trujillo, Alejandra Carmina Córdova-Ramírez, Montserrat Rivera-Álvarez, Gilberto David Elias-de-la-Cruz, Juan Carlos Olivares-Gazca, Guillermo J. Ruiz-Delgado and Guillermo J. Ruiz-Argüelles

Quality of life after ischaemic stroke—accent on patients with thrombolytic therapy

Intravenous thrombolysis is a widely approved treatment method for acute ischemic stroke (AIS). Nevertheless, there is a growing interest in its impact on functional outcomes and Health-related Quality of life...

Authors: Mihael Emilov Tsalta-Mladenov and Silva Peteva Andonova

A case report of isolated abducens nerve palsy: idiopathic or ophthalmoplegic neuropathy?

Abducens nerve is the most common nerve affected among other cranial nerves in terms of isolated ocular palsy. Despite its prevalence and progression made in neuroimaging, incidence of idiopathic cases continu...

Authors: Zainab Irshad Husain, Rawaa AlSayegh and Hani Humaidan

The epidemiology of common mental disorders in Libya: a systematic review

There has been a global increase in the prevalence of common mental disorders (CMD), particularly in conflict hotspots. The limited amount of resources is one of the key barriers to effective treatment within ...

Authors: Mansour Abdulshafea, Abdul Hakim Rhouma, Nadeem Gire, Ali AlMadhoob, Usman Arshad and Nusrat Husain

An insight into Alzheimer’s disease and its on-setting novel genes

According to the World Health Organisation, as of 2019, globally around 50 million people suffer from dementia, with approximately another 10 million getting added to the list every year, wherein Alzheimer’s d...

Authors: Jaanaky Vigneswaran, Sivaloganathan Anogh Muthukumar, Mohamed Shafras and Geetika Pant

Prognostic value of glucose fluctuation in patients undergoing thrombolysis or thrombectomy due to acute ischemic stroke

Hyperglycemia during acute ischemic stroke is associated with worse outcomes, and this glucose altitude may persist in the initial days. In this study, we investigate the effect of glucose fluctuations in the ...

Authors: Sibel Ciplak, Ahmet Adiguzel, Unal Ozturk and Yahya Akalin

Clinical and morphological features of SARS-COV-2 associated acute hemorrhagic necrotizing encephalopathy: case report

The current case report presents acute hemorrhagic necrotizing encephalopathy (AHNE) as an example of a fatal complication, the etiology of which could be coronavirus disease 2019 (COVID-19) with multiple orga...

Authors: Victor Vladimirovich Ermilov and Nikita Alexeevich Dorofeev

Rasmussen syndrome in a tropical environment: a study of six (6) observations

In sub-Saharan Africa, encephalitis of various etiologies is a major public health problem and Rasmussen syndrome is rarely diagnosed due to under-medicalization. The objective of this study is to describe the...

Authors: Carlos Othon Guelngar, Touré Mohamed Lamine, Barry Mamadou Ciré, Diakité Mamady, Konaté Mahadi, Djibo Hamani Bachir Abdoul, Sakadi Foksouna, Djibo Hassane Fatimata, Camara Naby, Kassa Dago François, Bah Fatimatou Korka, Camara Doussou, Millimono Victorine, Condé Salematou, Sakho Aminata, Diallo Mohamed Tafsir…

Isolated traumatic acute subdural haematoma: outcome in relation to age, Glasgow Coma Scale, and haematoma thickness

Traumatic acute subdural haematoma occurs in about 10–20% of patients with severe head injuries. This study aims to investigate the relation between outcome and the age, Glasgow Coma Scale on admission as well...

Authors: Mohamed A. Ragaee, Radwan Nouby Mahmoud, Mohamed Ahmed Alghriany and Wael M. A. Abd El-Ghani

Area postrema syndrome in neuromyelitis optica spectrum disorder: diagnostic challenges and descriptive patterns

Although area postrema syndrome (APS) is one of the core clinical features of neuromyelitis optic spectrum disorder (NMOSD), it is frequently misdiagnosed as gastrointestinal or systemic disorders. In this stu...

Authors: Eman M. Khedr, Hassan M. Farweez, Noha Abo Elfetoh, Eman R. Badawy, Sara Hassanein, Doaa M. Mahmoud and Ahmed Nasreldein

Role of neuro-sonography of peripheral nerves as a diagnostic and a differentiation tool of amyotrophic lateral sclerosis

Motor neuron disease is a heterogeneous group of progressive neurodegenerative disorders, most common of which is amyotrophic lateral sclerosis (ALS). There are many clinical and radiological criteria to diagn...

Authors: Rana Zakaria Ahmed Mohamed, Haitham Hamdy Salem, Hossam Moussa El-Sayed Sakr, Hossam-Eldin Mahmoud Afifi, Ahmed Mohammed Elsadek and Nagia Aly Fahmy

Gut microbiota in Parkinson’s disease patients: hospital-based study

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. There is accumulating evidence that link gut microbiota to symptomatology and pathophysiology of PD. The aim of this study was to ...

Authors: Eman M. Khedr, Anwar M. Ali, Enas Deaf, Hebatallah M. Hassan, Ahmed Alaa and Ayman Gamea

Migraine in patients with rheumatoid arthritis and its relation to disease activity

The comorbidity between rheumatoid arthritis (RA) and migraine is complex and not completely understood.

Authors: Hassan Abd-Elaty El-Sonbaty, Carmen Ali Zarad, Mohamed Rezk Mohamed and Ali Ahmed Abou Elmaaty

NeuroAid II (MLC901) and polypharmacy in stroke and the risk of hepatotoxicity: a case report

NeuroAid II (MLC901) is a promising therapy for stroke patients who present outside of therapeutic window for reperfusion therapy. Studies have proven its efficacy in ischemic stroke; however, data of drug saf...

Authors: Anna Misya’il Abdul Rashid, Mohamad Syafeeq Faeez Md Noh, Abdul Hanif Khan Yusof Khan, Wei Chao Loh, Janudin Baharin, Azliza Ibrahim, Liyana Najwa Inche Mat, Wan Aliaa Wan Sulaiman, Fan Kee Hoo, Fazah Akhtar Hanapiah and Hamidon Basri

Obsessive–compulsive disorder post-COVID-19: a case presentation

Since the emergence of the COVID-19 pandemic and the significant changes that impacted because of it, people around the world have been left dealing with its consequences—fear of becoming ill and dying, fear o...

Authors: Abdulmajeed A. Alkhamees

Does the second ischemic stroke herald a higher proportional risk for cognitive and physical impairment than the first-ever one?

Post-stroke cognitive and physical disabilities are common sequelae; however, it seems that the second ischemic stroke carries a higher proportional risk more than expected. In this study, we aimed to study se...

Authors: Mohammed Ezzat Elwan, Aktham Ismail Al-emam, Ahmed Nabil Munir and Mostafa Saleh Melake

Risk factors and impact of stigma on psychiatric patients in Sohag

Stigma among psychiatric patients is pervasive all over the world. Our aim in this study was to investigate risk factors for stigma related to psychiatric disorders and to demonstrate the major consequences of...

Authors: Taher Abdelraheem Sayed, Magda Mohamed Ali and Saber Hadad

Time to diabetic neuropathy and its predictors among newly diagnosed type 2 diabetes mellitus patients in Northwest Ethiopia

Despite the high number of patients suffering from the negative impact of diabetic neuropathy (DN) in Ethiopia, evidence regarding the time to DN and its predictors are not well document in Ethiopia. Therefore...

Authors: Sewnet Adem Kebede, Biruk Shalmeno Tusa, Adisu Birhanu Weldesenbet, Zemenu Tadesse Tessema and Tadesse Awoke Ayele

The effect of bilateral tDCS over dorsolateral prefrontal cortex on the cognitive abilities of men with opioid use disorder under methadone therapy: A sham-controlled clinical trial

Opioid use disorder (OUD) can have negative impact on cognitive functions. This study aims to evaluate the effect of bilateral transcranial direct-current stimulation (tDCS) over the right/left dorsolateral pr...

Authors: Hossein Mostafavi, Mohsen Dadashi, Alireza Armani Kia, Davod Ahmadi, Reza Pirzeh and Zakaria Eskandari

Functional gait assessment in early and advanced Parkinson’s disease

Postural instability and balance problems in patients with Parkinson’s disease (PD) can seriously affect the quality of life and lead to falls with a subsequent increase in the morbidity and mortality. Early i...

Authors: Hany Mohamed Eldeeb and Heba Samir Abdelraheem

Neurophysiological biomarkers of peripheral nervous system affection in patients with stable chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary disease (COPD) is accompanied by substantial systemic dysregulations that comprise systemic inflammation and neurohormonal activation in addition to many neurological involvements...

Authors: Hossam Abd El Monem Ali and Ahmed Salama Al-Adl

Clinical features contributing to the sit-to-stand transfer in people with Parkinson’s disease: a systematic review

The aim of this systematic review is to present the existing literature on the clinical motor, and non-motor factors contributing to sit-to-stand transfer in individuals with Parkinson's disease.

Authors: Charmaine Pearl Da Cunha, Pratiksha Tilak Rao and Suruliraj Karthikbabu

Dispensing patterns of drugs used for neuropathic pain and adherence to NeuPSIG guideline: an observational study

Neuropathic pain is a common chronic ailment that can be challenging to treat because of the heterogeneity of its etiologies, symptoms, and underlying mechanisms. Drugs to treat neuropathic pain are highly pre...

Authors: Bahia Chahine and Farah Al Souheil

Copeptin: a potential blood biomarker for acute ischemic stroke

Copeptin is a new blood biomarker for acute ischemic stroke which emerged to assist clinicians with decision-making. Serum copeptin can accurately reflect vasopressin concentration, which plays a role in aggra...

Authors: Mohammed I. Oraby, Rasha H. Soliman, Rehab M. Abd Elkareem and Amna I. Mohammed