Articles

Assessment of cognitive functions in patients with multiple sclerosis

About 40–70% of patients with multiple sclerosis (MS) develop cognitive impairment (CI) throughout their life. We aim to study the influence of MS on cognitive changes. This is a case–control study of fifty pa...

Authors: Tara A. Al-Falaki, Farqad B. Hamdan and Nawfal M. Sheaheed

Epidemiological profile of brain tumors in Cameroon: a retrospective study

Brain tumors represent group of neoplasms originating from intracranial tissues and the meninges. The aim of this study was to determine the epidemiological profile of brain tumors seen in a referral health ce...

Authors: Mathieu Motah, Daniel Gams Massi, Fabien Fouda Bekolo, Nkemontoh Akweseh Nju, Aurélien Ndoumbe, Mireille Moumi, Anne Sango, Paul Shu and Victor Eyenga

High leukotriene B4 serum levels increase risk of painful diabetic neuropathy among type 2 diabetes mellitus patients

Painful diabetic neuropathy is one of the most common complications of type 2 diabetes mellitus, with approximately 30–50% of people will experience diabetic neuropathy. Chronic hyperglycemia will cause an inf...

Authors: Kelvin Yuwanda, I Putu Eka Widyadharma, Dewa Putu Gde Purwa Samatra, I Made Oka Adnyana, Anna Marita Gelgel and I Komang Arimbawa

Electrophysiological characteristics and anatomical differentiation of epileptic and non-epileptic myoclonus

Electrophysiological techniques have been used for discriminating myoclonus from other hyperkinetic movement disorders and for classifying the myoclonus subtype. This study was carried out on patients with dif...

Authors: Mohammad Abu-Hegazy, Azza Elmoungi, Eman Eltantawi and Ahmed Esmael

A study of anxiety, depression and stress symptoms among Fayoum medical students during COVID-19 lockdown, Egypt

The widespread pandemic of COVID-19 virus carries not only physical hazards, but also major psychological effects especially among medical students. The aim was to investigate the psychological effects of COVI...

Authors: Mohamed R. Soltan, Shaimaa S. Soliman and Mariam E. Dawoud

Neurological sequelae of COVID-19: a review

The COVID-19 pandemic has produced a myriad of challenges, including identifying and treating neurological sequelae.

Authors: Christopher J. Peterson, Ashish Sarangi and Fariha Bangash

Reply to Letter to Editor: Is SARS-CoV-2 responsible for relapses of Parkinson’s disease?

Authors: Walaa A. Kamel, Ismail Ibrahim Ismail, Mohamed Ibrahim and Jasem Y. Al-Hashel

Pathophysiology of SARS-CoV-2-associated ischemic stroke is variegated

Authors: Fulvio A. Scorza, Ana C. Fiorini and Josef Finsterer

Cognitive impairment and depression in patients with relapsing–remitting multiple sclerosis depending on age and neuroimaging findings

Multiple sclerosis is an insidious, disabling, both physically and mentally, demyelinating disease of the central nervous system. This work aims to evaluate relationships between cognitive impairment in separa...

Authors: Oksana O. Kopchak and Tetiana A. Odintsova

Dilemma of migraine diagnosis and management among non-neurologists

Migraine is a common and debilitating disorder however there is a wide gap in its diagnosis and management. Many migraine patients present to non-neurologists, so it is of utmost importance that non neurologis...

Authors: Mai Fathy, Ahmed ElSadek, Sherien Farag, Shahinaz Helmy and Amr AbdElMoneim

Impact of vitamin D level in diabetic people with peripheral neuropathy

Diabetes mellitus (DM) is a metabolic disease which is complicated by occurrence of diabetic peripheral neuropathy (DPN). Vitamin D deficiency contributes to the etiology and progression of type 2 DM and devel...

Authors: Mohammad H. Assy, Nashwa A. Draz, Sabah E. Fathy and Mohammad G. Hamed

A volumetric magnetic resonance imaging study in migraine

Although migraine phenotype has been widely described, the explanation of migraine pathophysiology still has a gap that might be partly bridged by neuroimaging investigations. The aim of the study is to assess...

Authors: Laila Elmously Naguib, Ghada Saed Abdel Azim and Mohammed Abdelrazek Abdellatif

Impact of body mass index on duplex parameters of cranial vessels among the Egyptian population

Obesity is a major health problem that affects different vascular systems, including cerebrovascular circulation. Carotid duplex is the best screening tool for early diagnosis of cerebrovascular changes in rel...

Authors: Tarek A. Rageh, Mostafa Ghazally and Khaled O. Mohamed

Serum levels of leptin and adiponectin in patients with multiple sclerosis

The role of adipokines such as leptin and adiponectin in regulating the immunity has been documented, however data concerning their consequence on multiple sclerosis (MS) Egyptian patients are deficient. The a...

Authors: Rasha M. Fahmi, Amr E. Kamel, Dorreya A. Elsayed, Amal A. Zidan and Noha T. Sarhan

Neurological manifestations of COVID-19 infection: an umbrella review

Neurological involvements of COVID-19 are one of the most reported manifestations of this infection. This study aims to systematically review the previous systematic reviews which addressed the neurological ma...

Authors: Samad Shams Vahdati, Alireza Ala, Dara Rahmanpour, Elyar Sadeghi-Hokmabadi and Fateme Tahmasbi

Giant intracavernous aneurysm presenting with isolated trigeminal neuralgia: a case report

Trigeminal neuralgia (TN) commonly affects individuals aged more than 50 years and is mostly primary owing to trigeminal nerve neurovascular compression. We report a case of secondary TN attributed to a giant ...

Authors: Fadhilah Hani Ishak, Abdul Hanif Khan Yusof Khan, Mohd Naim Mohd Yaakob, Mohd Fandi Al Khafiz Kamis, Anna Misyail Abdul Rashid, Wei Chao Loh, Janudin Baharin, Azliza Ibrahim, Liyana Najwa Inche Mat, Wan Aliaa Wan Sulaiman, Fan Kee Hoo and Hamidon Basri

Paradoxical role of hepatocyte growth factor in ischemic stroke: stroke risk/stroke recovery

Hepatocyte growth factor (HGF) has an obvious pathological role in atherosclerosis and plaque instability leading to an acute ischemic stroke; however, its beneficial role in stroke recovery is still restricte...

Authors: Ibraheim Al-Ahmar, Noha Mohamed and Hosna Elshony

Does type and number of used substances affect the severity of illness in patients with substance use disorders?

Substance use disorders (SUD) are considered as serious mental illnesses, with variability of age of onset, duration of illness, and type of used substance among patients. The effect of type and number of subs...

Authors: Maha Ali Hassan, Mohamed Ayman Abdelhameed, Mostafa Mahmoud Abd El-Naem and Mohamed Helmy Abdelhafeez

Neurological manifestations in mild and moderate cases of COVID-19

The coronavirus disease due to SARS COVID-2 emerged from Wuhan city in China in December 2019 and rapidly spread to more than 200 countries all over the world as a global health pandemic. Its primary presentat...

Authors: Ghada Saed Abdel Azim and Marwa Abdellah Osman

Role of contrast-enhanced FLAIR MRI in diagnosis of intracranial lesions

MR imaging plays a significant role in detection and characterization of different brain diseases. The role of the post-contrast T1-weighted image magnetic resonance imaging (T1W MRI) sequence has been widely ...

Authors: Wessam Mustafa, Sherif Ali, Nadia Elgendy, Samer Salama, Lamiaa El Sorogy and Mohamed Mohsen

Case report on Cotard’s syndrome (CS) in a patient with schizophrenia: a rare case from Malaysia

Cotard’s syndrome (CS) is a neuropsychiatric condition marked by nihilistic delusional(s). Due to its rarity, misdiagnosis of the syndrome often occurs. The current case study is of a Malaysian woman who was m...

Authors: Natasha Subhas, Khin Ohnmar Naing, Chaw Su, Jiann Lin Loo, Aishah Farhana Shahbudin, Vevehkanandar Sivasubramaniam and Reenisha Thyagarajan

Assessment of anxiety and depression among hospitalized COVID-19 patients in Thailand during the first wave of the pandemic: a cross-sectional study

Anxiety and depression in hospitalized COVID-19 patients in Thailand during the first wave of the pandemic were investigated. Thai version of Hospital Anxiety and Depression Scale (HADS) was chosen as an instr...

Authors: Wajana Thaweerat, Wannarat Amornnimit Pongpirul and Wisit Prasithsirikul

Exploring the factors associated with coronaphobia among physicians during the COVID-19 outbreak in Egypt

Coronaphobia refers to intensified and persistent fears of contracting COVID-19 virus infection. This study aimed to evaluate the newly termed phenomenon, coronaphobia, and address its associated correlates am...

Authors: Mohamed Abdelghani, Mervat S. Hassan, Hayam M. Elgohary and Eman Fouad

Knowledge, attitudes, and impact of COVID-19 pandemic among neurology patients in Jordan: a cross-sectional study

The impacts of the COVID-19 pandemic on health services offered to patients with non-communicable diseases, including chronic neurological illnesses, are diverse and universal. We used a self-reported question...

Authors: Mohammad Athamneh, Qais Sa’di, Belal Aldabbour, Yousef Khader and Waleed Batayha

Predictors of parenting stress in parents of children diagnosed with autism spectrum disorder: a scoping review

Identifying the predictors of parenting stress in parents of children with autism spectrum disorder is crucial to provide the best health-care services.

Authors: Haytham Mohammad Al-Oran and Lee Khuan

Vitamin D receptor gene polymorphisms and idiopathic Parkinson disease: an Egyptian study

Accumulating data have suggested that vitamin D receptor (VDR) gene is a pretender gene for vulnerability to Parkinson disease (PD). This study aimed to assess the relationship of VDR gene polymorphisms (FokI ...

Authors: Ebtesam Mohamed Fahmy, Mohamed Elsayed Elawady, Sahar Sharaf, Sarah Heneidy and Rania Shehata Ismail

Trigeminal nerve stimulation: a recently approved treatment approach in attention deficit hyperactivity disorder

Attention-deficit hyperactivity disorder (ADHD) with its high prevalence is a growing area of concern and research, whereas exact underlying pathophysiology remains unknown. Behavioral therapy and multiple med...

Authors: Mazlum Çöpür and Sidar Çöpür

A case series of post COVID-19 mucormycosis—a neurological prospective

Direct neurological manifestations of coronavirus disease whether peripheral or central are reported worldwide. Yet, along the 3rd wave of the pandemic especially in India, an associated angioinvasive opportun...

Authors: Tamer Roushdy and Eman Hamid

Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India

Temporal lobe epilepsy is the most common type of focal onset seizure. Focal onset seizure with impaired awareness, previously known as complex partial seizure (CPS), account for 18–40% of all seizure types. H...

Authors: Aleena Elizabeth Andrews, Naufal Perumpalath, Juvaina Puthiyakam and Andrews Mekkattukunnel

Retractorless brain surgery: technical considerations

Retraction is necessary to access deep areas in the brain and skull base, but prolonged and forceful use of fixed retraction might be injurious. Several techniques were developed, in the concept of minimally i...

Authors: Wael Mohamed Nazim and Mohamed Abdelrahman Elborady

A comparison of cognitive performances between neuromyelitis optica spectrum disorder and multiple sclerosis patients in Indian context

To compare the frequency and pattern of cognitive impairment in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) patients.

Authors: Swati Kumar, Goutam Gangopadhyay, Atanu Biswas, Souvik Dubey, Alak Pandit, Shambaditya Das and Biman Kanti Ray

Brain tumor surgery in the elderly: a single institution experience of short-term outcome—a retrospective case study

There is an evolving concern in the management of brain tumors in the elderly. The number of elderly people (aged 65 years or more) increases progressively, and there is a considerable percent of brain tumors ...

Authors: Mostafa F. Tantawy and Wael M. Nazim

Etiological profile of new-onset seizures among adult Egyptians

New-onset seizure (NOS) is defined as the first seizure within a 24-h period ever experienced by the patient. A first-ever seizure can be the first manifestation of epilepsy. Or it may be a symptom of a brain ...

Authors: Mahmoud Hemeida Mahmoud, Eman Mahmoud Awad, Ahmed Khalil Mohamed and Mohamed Ahmed Shafik

The role of appendectomy in the development of Parkinson’s disease: a retrospective study in a teaching hospital in Jordan

Parkinson’s disease is a degenerative brain disease related to the accumulation of an abnormally aggregated alpha-synuclein protein. A hypothesis was presumed that this protein will be transported retrogradely...

Authors: Said Salah Dahbour, Aseel Subuh, Rama Haddad, Tulay Al-Samardali and Aladdin Dahbour

Quantitative motor unit potential analysis and nerve conduction studies for detection of subclinical peripheral nerve dysfunction in patients with compensated liver cirrhosis

Peripheral neuropathy is an underestimated problem of compensated liver cirrhosis despite its negative effect on quality of life. The aim was to assess the role of meticulous electrophysiological screening (ne...

Authors: Mostafa M. Elkholy and Ragaey A. Eid

Endocan serum levels in patients with low- and high-grade meningiomas: does this biomarker have an indicative role?

Meningiomas are one of the most common tumors of the brain and central nervous system. The key role of endocan in predicting tumor growth and prognosis has been shown for several types of cancers; however, thi...

Authors: Mohammad Javad Fattahi, Fatemeh Sedaghat, Mahyar Malekzadeh, Amir Ali Nejat, Maryam Poostkar, Yousef Saberi, Mousa Taghipour and Abbas Ghaderi

Cluster seizures and status epilepticus in new onset seizures among adult Egyptians

New onset seizure (NOS) is defined as the first seizure within a 24-h period ever experienced by the patient. Cluster seizures (CS) or status epilepticus (SE) can be the first manifestation of epilepsy or it m...

Authors: Mahmoud Hemeida Mahmoud, Eman Mahmoud Awad, Ahmed Khalil Mohamed and Mohamed Ahmed Shafik

Is SARS-CoV-2 responsible for relapses of Parkinson’s disease?

Authors: Fulvio A. Scorza, Josef Finsterer and Ana C. Fiorini

Diagnostic value of brain MR imaging and its correlation with clinical presentation and cognitive functions in idiopathic intracranial hypertension patients

Idiopathic intracranial hypertension (IIH) is a neurological disorder of unknown etiology and ambiguous pathophysiology due to cerebrospinal fluid dysregulation. This study is designed to evaluate the role of ...

Authors: Ali Ahmed Abou Elmaaty, Carmen Ali Zarad, Tamer Ibrahim Belal and Tamer Sabry Elserafy

Impact of depression on quality of life in systemic lupus erythematosus patients

Depression is common in systemic lupus erythematosus (SLE) and is an unmeasured risk factor, yet its symptoms can be neglected in standard disease evaluations. The purpose of this study was to assess the frequ...

Authors: Eman M. Khedr, Rania M. Gamal, Sounia M. Rashad, Mary Yacoub and Gellan K. Ahmed

Study of cognitive impairment and genetic polymorphism of SLC41A1 (rs11240569 allele) in Parkinson’s disease in Upper Egypt: case-control study

Parkinson’s disease is one of the neurodegenerative disorders that is caused by genetic and environmental factors or interaction between them. Solute carrier family 41 member 1 within the PARK16 locus has been...

Authors: Hamdy N. El-Tallawy, Tahia H. Saleem, Wafaa M. Farghaly, Heba Mohamed Saad Eldien, Ashraf Khodaery, Sherif A. Sayed, Ahmed A. Helaly and Hassan Mohammed Elnady

Surgical management of tentorial meningiomas: case series

There are several surgical strategies involved in the treatment of patients with tentorial meningioma, and choosing the most appropriate one is not straight forward. Our study aims to illustrate our experience...

Authors: Hussein Mohammed Soffar, Mohamed Mohsen El Shimy, Hieder Al-Shami and Ahmed M. Salah

Idiopathic intracranial hypertension with multiple cranial nerve palsies in 10 years old thin Sudanese boy: case report

Idiopathic intracranial hypertension is a rare neurological disorder of unknown etiology. It is characterized by symptoms and signs of raise intra cranial pressure, normal brain neuroimaging, and high opening ...

Authors: Mumen Abdalazim Dafallah, Elsanosi Habour, Esraa Ahmed Ragab, Zahraa Mamoun Shouk and Mohammed Izzadden

Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study

Disturbances in structural and synaptic plasticity have been linked to depression and suicidal ideation. One of the major neurotrophic factors, the brain-derived neurotrophic factor (BDNF), is involved in the ...

Authors: Amira Mohamed Yousef, Ghada Mohamed Salah El-Deen, Abdallah Saad Ibrahim and Amany Elshabrawy Mohamed

Case reports of cerebral sinus venous thrombosis in COVID-19 patients

Coronavirus disease 2019 (COVID-19) pandemic has started in December 2019 and still ongoing. The disease has been expanding rapidly with a high variety of phenotypes from asymptomatic, mild respiratory tract i...

Authors: Prysta Aderlia Sitanggang, Kumara Tini, Ni Made Susilawathi, Ida Ayu Sri Wijayanti, Putu Utami Dewi and Dewa Putu Gde Purwa Samatra

A novel surgical rotation overlapping craniotomy technique for the management of non-syndromic anterior plagiocephaly

Nonsyndromic anterior plagiocephaly is one of the most common types of craniosynostosis. Different surgical techniques to correct this deformity have been developed with dissatisfaction among many surgeons. In...

Authors: Mohamed Reda Rady, Mamdouh Abo Elhassan and Omar Youssef

Extradural anterior clinoidectomy in surgical management of clinoidal meningiomas

Despite the recent advances in skull base surgery, microsurgical techniques, and neuroimaging, yet surgical resection of clinoidal meningiomas is still a major challenge. In this study, we present our institut...

Authors: K. El-Bahy, Ashraf M. Ibrahim, Ibrahim Abdelmohsen and Hatem A. Sabry

Non-protected carotid artery stenting for symptomatic carotid stenosis in low resource settings

The use of a distal cerebral protection device during extracranial carotid artery stenting is still a matter of debate. The aim of this work was to evaluate the safety of performing carotid artery stenting pro...

Authors: Ayman H. El-Sudany, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros and Ahmed El-Bassiouny

Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Neuropsychiatric systemic lupus erythematosus (NPSLE) is well known for its varying presentations and poor outcomes, but little is evident about its distribution and characteristics among the Bangladeshi popul...

Authors: Fahima Hossain, Mohammad Delwer Hossain Hawlader, Dipak Kumar Mitra, Mohammad Hayatun Nabi and Md. Mujibur Rahman

Rare case of recurrent stroke in a patient with eosinophilic granulomatosis with polyangiitis: a case report

Central nervous system involvement is rarely described in eosinophilic granulomatosis with polyangiitis (EGPA) and occurs in 5–9% of patients. Among central nervous system manifestations, cerebral infarctions ...

Authors: Mirjana Arsenijević, Nikola Ivančević, Dejana Jovanović, Milan Radović and Ivana Berisavac