Articles

Cardio embolic stroke and blood biomarkers: diagnosis and predictors of short-term outcome

The brain is a productive source of a variety of enzymes and any brain injury like a stroke to brain tissue could similarly result in an increase in these enzymes in cerebrospinal fluid and serum. Evaluation o...

Authors: Wafaa S. Mohamed, Elhady A. Abd ElGawad, Amal SE. ElMotayam and Sabah E. Fathy

Lower limb weakness with gyrus rectus hematoma: an unusual presentation of paraclinoid aneurysm; a case report with review of literature

Lower limb weakness is usually a feature of ruptured anterior communicating (ACom) aneurysms due to spasm of the anterior cerebral arteries. Paraclinoid aneurysms, in addition to other cardinal features of sub...

Authors: Amey P. Patankar and Maulik Vaja

Assessment of the optic nerve and its arterial supply by ultrasound imaging in multiple sclerosis patients

Transorbital sonography (TOS) has emerged as a promising assessment tool of the optic nerve and orbital arterial supply in multiple sclerosis (MS) patients.

Authors: Manal Mahmoud Al Kattan, Amira Ahmed Labib, Rania Shehata Ismail, Alshaimaa M. Aboul fotouh and Emad El Din Mostafa Mohammed

Screening for cognitive impairment in Arabic-speaking Hajj pilgrims

Although cognitive impairment is common in the elderly population, studies investigating its rate in Hajj pilgrims are lacking.

Authors: Ahmad S. Alzahrani, Faisal Alhumaidi, Abdulaziz Altowairqi, Waad Al-Malki and Israa AlFadhli

Early functional outcome after IV rTPA administration in Egyptian acute ischemic stroke patients

Intravenous thrombolysis has become a standard practice in eligible patients with acute ischemic stroke (AIS). Functional outcome after AIS is a major concern for patients, families, and neurologists. Identify...

Authors: Mohamed A. Elsayed, Husam Salah, Asmaa Sabbah, Ghada Hatem and Mona K. Moawad

Long-term EEG monitoring and positron emission tomography in evaluating patients with drug-resistant epilepsy

Drug-resistant epilepsy (DRE) is a commonly faced problem in epilepsy practice associated with great psychosocial consequences. This work aimed to study the role of seizure semiology analysis (SSA), long-term ...

Authors: Abdelmoneim Ahmed Nagy Eissa, Wafik Said Bahnasy, Al Siagy Ali Abd Elaziz Salama, Elsayed Ali Mohamed Tag Eldin and Hazem Abdelrahman Fayed

Quantitative d-dimer level and anticoagulant therapy in idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a syndrome characterized by elevated intracranial pressure (ICP) of unknown etiology

Authors: Hala Shaheen, Sayed Sobhy, Sherine El Mously, Mohamed El Khatib and Amany Hamdy

Early hematoma expansion in primary intracerebral hemorrhage: incidence and predictors

Hematoma expansion (HE) is the leading cause of early neurological deterioration, poor functional outcome, and increased mortality in patients with spontaneous intracerebral hemorrhage (S-ICH). The study aimed...

Authors: Hany Hamed Abd Elhady Helal, Wafik Said Bahnasy, Azza Abbas Ghali and Mohammed Osman Rabie

The emerging role of serum zinc in motor disability and radiological findings in patients with multiple sclerosis

The role of serum Zinc in the pathogenesis of relapsing remittent multiple sclerosis (RRMS) and its impact on motor disability and radiological findings remains a matter of debate.

Authors: Mohammed I. Oraby, Mona Hussein, Rehab Abd Elkareem and Eman Elfar

Lesion homogeneity on diffusion-weighted imaging is a marker of outcome in acute ischemic stroke

MRI Diffusion-weighted imaging (DWI) lesion volume, pattern, and location have all been used to predict outcome of acute ischemic stroke. We hypothesized that homogeneity within the DWI lesion may also be asso...

Authors: Shady Mourad Boss, Ramez Reda Moustafa, Magdy Ahmed Moustafa, Ahmed El Sadek, Mohamed Mahmoud Mostafa and Hany Mohamed Aref

Epidemiology of dystonia, chorea, and athetosis in Al Quseir City (Red Sea Governorate), Egypt

Movement disorders are common neurological problems, but epidemiological studies are lacking in our locality. Type of movement disorder depends on the site of the lesion and the type of pathologic changes.

Authors: Reda Badry, Mohamed A. Abdelhamed, Mohamed A. M. Sayed, Abeer Abd ElHady and Mohamed Mostafa

Treatment satisfaction and adherence to medications among multiple sclerosis patients in Saudi Arabia

Despite the apparent benefits of disease-modifying drug (DMD) use among multiple sclerosis (MS) patients, their rates of adherence are often variable and in some cases are quite low.

Authors: Adel Alhazzani, Mohammed Alqahtani, Noof Alamri, Leen Sarhan, Shahad Alkhashrami and Mohammed Alahmarii

Chemotherapy-induced cognitive impairment in hematological malignancies

Chemotherapy-induced cognitive impairment (CICI) is one of the most prominent side effects as it negatively impacts activities of daily life of the affected role. These problems can range from subtle to severe...

Authors: Mohamed Gamal Kotb, Abd El Rahman Soliman, Rasha Ibrahim Ibrahim, Rasha Magdy Mohamed Said and Mona Mokhtar Wahid El Din

Tracking epilepsy and autism

There is conflicting data as to the prevalence of seizures and the relevance of epileptiform EEGs in autistic children. With the focus primarily on aetiology in autism research, very little emphasis has been p...

Authors: G. V. Lamb, R. J. Green and S. Olorunju

Correlation between brain magnetic resonance imaging, cognitive dysfunction and physical dysability in multiple sclerosis

Montreal Cognitive Assessment test (MoCA) is a brief, sensitive test that has been recommended as a reliable tool to detect mild cognitive impairment. Associations between brain imaging measures and cognitive ...

Authors: Ali A. Abou Elmaaty, Mohamed E. Flifel and Carmen A. Zarad

Psychosomatic complaints profile in patients with type 2 diabetes: a matched case-control study

To compare the prevalence of psychosomatic symptoms and their mean scores of profiles in diabetic patients and sample of sex-age-matched healthy controls.

Authors: Zahra Heidari, Awat Feizi, Ammar Hassanzadeh Keshteli, Hamid Afshar, Hamidreza Roohafza and Peyman Adibi

Optical coherence tomography and cognitive dysfunction in Parkinson disease

Parkinson’s disease (PD) is a progressive neurodegenerative disease of aging. Optical coherence tomography (OCT) is a simple noninvasive imaging technique to estimate the retinal nerve fiber layer (RNFL) thick...

Authors: Takwa H. M. Elkhatib, Noha A. Hashim, Engy M. Emad, Hossam Zein and Lamiaa El-aidy

Association between metabolic syndrome and atherothrombotic stroke: a clinical study in tertiary care hospital, Minia, Egypt

Stroke is the most common reason for disability and the third cause of mortality in the world per year. Metabolic syndrome (MetS) is known as an independent risk factor of coronary artery disease and stroke.

Authors: Amal T. Khafagy, Nermin A. Hamdy, Enas M. Hassan, Mohamed A. Yehia, Muhammad M. Ismail, Mohamed M. Abdelkader and Nashwa M. Shawky

Cerebral vasomotor reactivity in border zone infarcts; a transcranial Doppler study

Many reports have emphasized that watershed infarcts are the consequence of hemodynamic compromise, but other reports have suggested that this is not always the case and have suggested that embolization plays ...

Authors: Hossam Afify, Shahinaz M. Helmy, Lobna M. El-Nabil, Naglaa M. El-khayat, Nevine M. El Nahas and Magd F. Zakaria

Cystatin C as a predictor for carotid artery steno-occlusive disease in non-cardioembolic ischemic stroke

Stroke is the third leading cause of death in developed nations. Ultrasonography (US) of the carotid arteries is the modality of choice for diagnosis and monitoring of cases of atheromatous disease. Cystatin C...

Authors: Maha Atef Zaki, Sahar Abd Atty, Alshaimaa M. Aboul fotouh and Nancy Samir Wahdan

The potential value of capsaicin in modulating cognitive functions in a rat model of streptozotocin-induced Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder.

Authors: Manal A. Shalaby, Howaida A. Nounou and Maha M. Deif

Role of single nucleotide polymorphisms (SNPs) in common migraine

Single nucleotide polymorphisms (SNPs) may act as biological markers, as they can relate to the genes that are associated with various complex diseases such as heart diseases, diabetes, cancer, schizophrenia, ...

Authors: Sukhvinder Kaur, Arif Ali, Uzair Ahmad, Yaser Siahbalaei, A. K. Pandey and Balkirat Singh

Radiofrequency thermocoagulation in cases of atypical trigeminal neuralgia: a retrospective study

Trigeminal neuralgia (TN) is the most common cause of neuropathic facial pain. Atypical TN are usually refractory to conventional medical treatments and the standard microvascular decompression surgeries that ...

Authors: Mert Akbas, Haitham Hamdy Salem, Tamer Hussien Emara, Bora Dinc and Bilge Karsli

Post-stroke executive dysfunction and verbal fluency negatively correlated to IL8

Patients with acute ischemic stroke are at a higher risk of developing cognitive impairment which could be often attributed to cytokine activation.

Authors: Hala A. Shaheen, Lamiaa I. Daker, Mohammed M. Abbass and Asmaa A. Abd El Fattah

Music therapy as a therapeutic tool in improving the social skills of autistic children

The Cochrane Collection reviews of randomized clinical trials (RCT) showed a favorable result of music therapy (MT) on individuals with autism spectrum disorder (ASD) compared with a placebo treatment.

Authors: Geetha Bharathi, Anila Venugopal and Balachandar Vellingiri

Effect of valproate versus levetiracetam monotherapy on reproductive functions in newly diagnosed epileptic males

Antiepileptic drugs are responsible for reproductive dysfunction in male epileptic patients.

Authors: Wafaa S. Mohamed, Rania S. Nageeb, Noha A. Hashim and Alaa A. Omran

Unusual neurosurgical emergency in Paget’s disease of the skull: a case report and review of the literature

Paget’s disease of bone is usually asymptomatic in most cases. The neurosurgeon should be familiar with the common presentation and complications. The rare presentation of this case of Paget’s disease of the s...

Authors: Ahmed Hamdy Ashry, Dina Mahmoud Alnajjar, Amr Abdelmonam Abdelaziz Mostafa Elkatatny and Mohamed Ahmed Eissa

Relative frequency and prognosis of vascular aphasia (follow-up at 3 months) in the Neurology Department of Assiut University Hospital

Post-stroke aphasia (PSA) is a disabling complication after stroke leading to impairment of quality of life. It was reported to develop in one third of patients with stroke and in two thirds of patients with r...

Authors: Hamdy Naguib El-Tallawy, Adel Hassanein El Sayed Gad, Anwar Mohamed Ali and Manar Nasr Abd-El-Hakim

Influence of percentage of body-weight support on gait in patients with traumatic incomplete spinal cord injury

Body-weight-supported treadmill training (BWSTT) is a treatment method to help patients with incomplete spinal cord injuries to restore the capability to walk again.

Authors: Moataz M. El Semary and Lamiaa I. Daker

Sex differences among epileptic patients: a comparison of epilepsy and its impacts on demographic features, clinical characteristics, and management patterns in a tertiary care hospital in Egypt

Epilepsy is one of the most common neurological conditions. We aimed to identify sex differences in the demographic, clinical features, and treatment strategies in epileptic patients.

Authors: Nirmeen Kishk, Husam Mourad, Sahar Ibrahim, Reham Shamloul, Aiman Al-Azazi and Nevin Shalaby

Do core stability exercises improve upper limb function in chronic stroke patients?

Upper limb paresis is a common problem in patients with stroke.

Authors: H. El-Nashar, A. ElWishy, H. Helmy and R. El-Rwainy

Tumor necrosis factor alpha in peripheral neuropathy in type 2 diabetes mellitus

To compare serum levels of tumor necrosis factor alpha (TNF-α) between type 2 diabetes mellitus patients with and without peripheral neuropathy (PN). Also, to study the relation between peripheral nerves condu...

Authors: Wafik M. El Sheikh, Ibrahim E. Alahmar, Gelan M. Salem and Mohamed A. El-Sheikh

Probable Creutzfeldt-Jakob disease—a case report at Suez Canal University Hospital, Egypt

Among transmissible spongiform encephalopathies, Creuzfeldt-Jakob disease is considered a rare neurodegenerative disorder. The clinical features include rapid progressive dementia and myoclonic jerks, which pr...

Authors: Mohamed Negm and Ehab Hashish

Relationship between periodic limb movement and seizure recurrence in genetic generalized epilepsy

Although periodic limb movements are prevalent among patients with epilepsy, the exact relationship between these movements and epilepsy remains elusive.

Authors: Mohamed Mohamed Hamdy, Amr Mohamed Elfatatry, Jaidaa Farouq Mekky and Eman Hamdy

Could vitamin D deficiency have an impact on motor and cognitive function in Parkinson’s disease?

Multiple epidemiological data showed a significant higher prevalence of hypovitaminosis D in patients with Parkinson’s disease (PD).

Authors: Rasha H. Soliman, Mohammed I. Oraby, Mona Hussein, Sanaa Abd El-Shafy and Sara Mostafa

Cognitive assessment of idiopathic intracranial hypertension patients

Idiopathic intracranial hypertension (IIH) is a disorder of unknown etiology. Goals of treatment are to preserve vision and alleviate symptoms, including intractable headache, pulsatile tinnitus, and nausea. C...

Authors: Iman A. Elbanhawy, Gihan M. Ramzy, Amal S. Ashour and Diana M. Khedr

Cerebrovascular reactivity recovery following carotid angioplasty and stenting

Internal carotid artery high-grade stenosis is a major cause of stroke. Carotid angioplasty and stenting (CAS) is a reasonable approach for treatment of certain patients. Cerebrovascular reactivity (CVR) evalu...

Authors: Saher El-Sayed Hashem, Ehab Shaker Belal, Montaser Moawad Hegazy, Ahmed Ali El-Bassiony, Sandra Mohamed Ahmed and Islam I. Zaid

Public knowledge of warning signs and risk factors of cerebro-vascular stroke in Ismailia Governorate, Egypt

Knowledge and awareness of cerebro-vascular stroke (CVS) warning symptoms and risk factors is deficient in the general population in the developing countries.

Authors: Ahmed Osama, Yossri Ashour, Reda Abd El-Razek and Ibrahim Mostafa

Repetitive TMS in treatment of resistant diabetic neuropathic pain

Diabetes mellitus is a clinical syndrome characterized by hyperglycemia caused by respective or absolute deficiency of insulin. Painful neuropathy in diabetic population is popular, impacting numerous chronic ...

Authors: Ann A. Abdelkader, Amira M. El Gohary, Husam S. Mourad and Dina A. El Salmawy

Prevalence of Alzheimer dementia in Upper Egypt (desert areas)

Alzheimer’s disease (AD) is the commonest type of Dementia worldwide. It rapidly increases with aging especially over 70 years.

Authors: Hamdy N. A. EL Tallawy, Wafaa M. A. Farghaly, Mohamed Abd El Hamed, Reda Badry, Khaled Usama, Ghaydaa A. Shehata, Amal M. Tohamy, Khaled O. Abdulghani, Mostafa K. Ghanem, Mohamed A. Sayed, Ahmed H. Yousef, Heba S. Hashem and Tarek A. Rageh

Refractory epilepsy and obstructive sleep apnea: is there an association?

A high prevalence of obstructive sleep apnea (OSA) has been reported in medically refractory epilepsy patients, and there is increasing evidence that treatment of OSA in refractory epilepsy patients would redu...

Authors: Hebatallah R. Rashed, Mohamad A. Tork, Lobna M. El-Nabil, Naglaa M. El-Khayat, Nahed S. Ahmed, Salem T. Abdelhady, Khaled O. Abdulghani and M. Ossama Abdulghani

Comment to “Diabetic peripheral neuropathy: the potential role of vitamin D deficiency” by Oraby et al.

Authors: Marco Baldrighi and Gian Carlo Avanzi

Neuro-ophthalmological biomarkers of visual outcome in newly diagnosed idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a disorder of unidentified etiology characterized by raised intracranial pressure (ICP) without clinical, laboratory, or radiological evidence of intracranial path...

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Mahmoud Ebrahim Mostafa Elhassanien, Amr Fawzy Sharaf and Hagar Ahmed Khalid

Decompressive craniectomy in malignant hemispheric infarction: favorable outcome and disability

Patients with malignant middle cerebral artery (MCA) infarction are prone to a mortality rate of 70–80%. Decompressive craniectomy (DC) has been used as an important treatment modality to control refractory in...

Authors: Ahmed Elsayed and Adham Elsayed

Non-motor symptoms in newly diagnosed Parkinson’s disease patients

The non-motor symptoms (NMSs) in Parkinson’s disease (PD) patients have greater effects on their quality of life compared to the motor symptoms; however, they are under-recognized.

Authors: Osama A. Ragab, Yasser A. Elheneedy and Wafik S. Bahnasy

Role of superficial peroneal sensory potential and high-resolution ultrasonography in confirmation of common peroneal mononeuropathy at the fibular neck

Common peroneal mononeuropathy at the fibular neck (CPN) is one of the most frequent neuropathies of the lower extremities. Nerve conduction studies (NCS) have been used to confirm the diagnosis of CPN and loc...

Authors: Rania S. Nageeb, Wafaa S. Mohamed, Ghada S. Nageeb, Eman Al Desoky and Taghreed M. Azmy

Post-bariatric surgery peripheral neuropathies: Kuwaiti experience

Obesity is a major global health problem. Kuwait has a very high prevalence of obesity, and consequently, the number of bariatric surgeries is rising.

Authors: Hanaa M. Rashad, Doaa Youssry, Dina F. Mansour, Ayman Kilany, Jasem Y. Al-Hashel, Adnan J. Khuraibet, Walaa A. Kamel and Rossen T. Rousseff

The NIHSS score can predict the outcome of patients with primary intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is characterized to be the most lethal form of stroke, with high rates of mortality, not only during the acute phase (39%), but also 3 months later (33.5%) with a significant lon...

Authors: Mohammed Elsayed Mahdy, Nesma Abdelmonem Ghonimi, Tamer Sabry Elserafy and Wael Mahmoud

Prevalence of migraine in Upper Egypt

Migraine is a significant health problem due its frequency and accompanying morbidity.

Authors: Hamdy N. El-Tallawy, Wafaa M. Farghaly, Mohamed A. Abdelhamed, Reda Badry, Tarek A. Rageh, Wael T. Soliman, Khaled O. Abdulghani, Mahmoud Hassan, Sayed Sobhy and Ghaydaa A. Shehata

Ankle-brachial index in ischemic stroke: risk factor correlation and prognostic value

Ankle-brachial index (ABI) is not only a marker of lower limb peripheral arterial disease (PAD), but may also reflect the severity of systemic atherosclerosis.

Authors: H. Afify, S. Noshy, A. Gaber and T. Kamel