Articles

Extradural anterior clinoidectomy in surgical management of clinoidal meningiomas

Despite the recent advances in skull base surgery, microsurgical techniques, and neuroimaging, yet surgical resection of clinoidal meningiomas is still a major challenge. In this study, we present our institut...

Authors: K. El-Bahy, Ashraf M. Ibrahim, Ibrahim Abdelmohsen and Hatem A. Sabry

Non-protected carotid artery stenting for symptomatic carotid stenosis in low resource settings

The use of a distal cerebral protection device during extracranial carotid artery stenting is still a matter of debate. The aim of this work was to evaluate the safety of performing carotid artery stenting pro...

Authors: Ayman H. El-Sudany, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros and Ahmed El-Bassiouny

Awake surgery for lesions near eloquent brain under scalp block and clinical monitoring: experience of single center with limited resources

Surgery of the brain tumors near eloquent areas carries the risk of either disabling neurological deficit or inadequate resection with bad prognosis in both situations. Awake surgery is the gold standard proce...

Authors: Esam Abdelhameed, Mohamed Shebl Abdelghany, Hazem Abdelkhalek and Hytham Ibrahim Shokry Elatrozy

Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Neuropsychiatric systemic lupus erythematosus (NPSLE) is well known for its varying presentations and poor outcomes, but little is evident about its distribution and characteristics among the Bangladeshi popul...

Authors: Fahima Hossain, Mohammad Delwer Hossain Hawlader, Dipak Kumar Mitra, Mohammad Hayatun Nabi and Md. Mujibur Rahman

Rare case of recurrent stroke in a patient with eosinophilic granulomatosis with polyangiitis: a case report

Central nervous system involvement is rarely described in eosinophilic granulomatosis with polyangiitis (EGPA) and occurs in 5–9% of patients. Among central nervous system manifestations, cerebral infarctions ...

Authors: Mirjana Arsenijević, Nikola Ivančević, Dejana Jovanović, Milan Radović and Ivana Berisavac

Duplex ultrasonography as prognostic tool of acute ischemic stroke patients

Cerebral stroke is a major source of mortality and morbidity. Duplex ultrasonography is used to evaluate carotid and cerebral arteries. The objectives of this work are to study the correlation between carotid ...

Authors: Mohamed El-Sayed El-khatib and Shereen Ahmed El Ahwal

Electrophysiological biomarkers of central nervous system affection in cases of chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary disease is associated with significant systemic abnormalities which includes systemic inflammation and neurohormonal activation that are considered the main mechanisms of the path...

Authors: Hossam Abd El Monem Ali and Ahmed Salama Al-Adl

Intravenous thrombolysis outcome in posterior vs anterior circulation stroke in a tertiary stroke center in Egypt

Intravenous thrombolysis (IVT) with alteplase is the first-line therapy for acute ischemic anterior and posterior circulation strokes (ACS and PCS).

Authors: Nourhan Abdelmohsen Taha, Hala El Khawas, Mohamed Amir Tork and Tamer M. Roushdy

Ondine’s curse, a fatal infarction diagnosed by polysomnography and saved by ventilation: a case report

Lateral medullary syndrome causing Ondine’s curse is a rare yet fatal brainstem infarction. Any patient presenting with lateral medulla infarction ought to be well observed and a polysomnography must be ordere...

Authors: Hany Aref, Tamer Roushdy, Amr Zaki and Nevine El Nahas

How patients with schizophrenia “as a Victim” cope with violence in Indonesia: a qualitative study

There is increasing concern about the level of violence and people with schizophrenia. However, research about violence in correlation with schizophrenia mostly focuses on patients as offenders rather than vic...

Authors: Iyus Yosep, Henny Suzana Mediani, Linlin Lindayani and Aat Sriati

Omentin-1: a biomarker in large artery ischaemic stroke patients

Omentin-1 is a novel adipocytokine that is related to atherosclerosis-based ischaemic cardiovascular disease and stroke. Previous studies have linked its lower levels with poor stroke outcomes. We aimed to ass...

Authors: Elham Nasif, Osama A. Ragab, Mahmoud E. Elhassanien and Ayman M. Al-Malt

Risk homozygous haplotype regions for autism identifies population-specific ten genes for numerous pathways

Recessive homozygous haplotype (rHH) mapping is a reliable tool for identifying recessive genes by detecting homozygous segments of identical haplotype structures. These are shared at a higher frequency amongs...

Authors: Swati Agarwala and Nallur B. Ramachandra

Neurological manifestations and neuroimaging findings in patients with SARS-CoV2—a systematic review

The COVID-19 pandemic has drastically affected everyone in a hit or miss manner. Since it began, evidence of the neuro-invasive potential of the virus has been intensifying significantly. Several pathways have...

Authors: Nikita Mohan, Muhammad Ali Fayyaz, Christopher del Rio, Navpreet Kaur Rajinder Singh Khurana, Sampada Sandip Vaidya, Esteban Salazar, John Joyce and Amrat Ayaz Ali

Mechanical thrombectomy (MT) for acute ischemic stroke (AIS) in COVID-19 pandemic: a systematic review

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially, COVID-19 is a disease that attacks the respiratory tract, but now the clinica...

Authors: Aditya Kurnianto, Dodik Tugasworo, Yovita Andhitara, Retnaningsih, Rahmi Ardhini and Jethro Budiman

Telephone-based assessment of multiple sclerosis patients at Ain Shams University Hospital in the coronavirus disease 2019 pandemic

Assessment of multiple sclerosis (MS) patients during the era of the coronavirus disease 2019 (COVID-19) pandemic was confronted with the overwhelmed healthcare facilities in Egypt and fear of the patients to ...

Authors: Mohamed A. Abdel Hafeez, Dina A. Zamzam, Mahmoud S. Swelam, Alaa Abo Steit, Janet Masoud, Azza Abdel Nasser, Ahmed Hazzou, Eman Hamid, Hany Aref, Magd F. Zakaria and Mohamed M. Fouad

Determinants of quality of life changes with plasmapheresis in patients with myasthenia gravis

Immunomodulation, including IVIG and plasma exchange, is useful for a crisis or severe exacerbation. Plasma exchange may be slightly faster and more effective in a myasthenic crisis than IVIG. The aim of the c...

Authors: Ibraheim Al-Ahmer and Hosna Elshony

Epidemiological profile of psychiatric illnesses in the province of Taza, Morocco: case of a study on a schizophrenic sub-population in the Ibn Baja Hospital

The objective of this study is to assess the prevalence of major psychiatric disorders and to plot some characteristics of the schizophrenic sub-population in the study area.

Authors: El Hassan Ouanouche, Hasnae Lamine, Asmae Tliji, Hajar Hourmattallah, Ali Ouichou, Aboubaker El Hessni and Abdelhalim Mesfioui

A review on SARS-CoV-2 and stroke pathogenesis and outcome

Severe acute respiratory syndrome corona virus 2 hit strongly and hardly the entire globe for more than 1 year with a morbidity exceeding 139 million and a mortality approaching 3 million worldwide since its e...

Authors: Tamer Roushdy and Eman Hamid

Botulinum toxin type A for painful diabetic neuropathy: an open-label study

A large proportion of painful diabetic neuropathy cases either do not respond or are intolerant to the currently available oral and physical therapies. There is encouraging evidence from a small number of stud...

Authors: Shahinaz Helmy, Tamer Emara and Amr Abdel Menem

COVID-19 Infection Stigma Scale: psychometric properties

Stigma has been noticed towards patients with COVID-19 in several regions of the world. This social discrimination has contributed to delay in diagnosis and treatment. Also, it may increase the suffering of th...

Authors: Hayam Mohammed Elgohari, Medhat Mohamed Bassiony, Mohammad Gamal Sehlo, Usama Mahmoud Youssef, Heba Mohamed Ali, Islam Shahin, Dina Sameh Elrafey and Rehab Saeed Mahdy

Unexplained worsening of parkinsonian symptoms in a patient with advanced Parkinson’s disease as the sole initial presentation of COVID-19 infection: a case report

Parkinson’s disease (PD) is a neurodegenerative condition that has been reported following viral infections in rare occasions. Several neurological complications have emerged in association with coronavirus di...

Authors: Walaa A. Kamel, Ismail Ibrahim Ismail, Mohamed Ibrahim and Jasem Y. Al-Hashel

Reflex memory theory of acquired involuntary motor and sensory disorders

Explicit and implicit memories are conserved but flexible biological tools that nature uses to regulate the daily behaviors of human beings. An aberrant form of the implicit memory is presumed to exist and may...

Authors: Matthias Oyigeya

Evaluation of risk factors for cerebral palsy

Cerebral palsy (CP) has been identified as one of the most important and common causes of childhood disabilities worldwide and is often accompanied by multiple comorbidities. CP is defined as a group of disord...

Authors: Dina Salama Abd Elmagid and Hend Magdy

The relationship of HLA-G 14-bp insertion/deletion genetic polymorphism to the risk of multiple sclerosis and its clinical phenotypes

Human leukocyte antigen (HLA)-G molecule has been suggested to have a potential immunomodulatory role in multiple sclerosis (MS). Genetic variant sites of HLA-G molecule have been reported to be associated wit...

Authors: Wafaa M. Farghaly, Heba M. Saad Eldien, Mohammed A. Sayed, Hassan M. Elnady, Ashraf Khodeary, Abdelhady R. Abdel-Gawad, Hamdy N. El-Tallawy, Mohammed G. Abdellatif and Hazem K. Alhewaig

The interictal activities load and cognitive performance of children with typical absence epilepsy

The description of childhood absence epilepsy (CAE) a benign self-limited generalized epilepsy has become a matter of debate. The objectives of this work were to evaluate the existence of psychiatric and cogni...

Authors: Shereen Ahmed ELAhwal, Yasser Abo Elfotoh El-Heneedy, Wafik Said Bahnasy, Reham Abdel Rahman Amer and Khaled Hussein Rashed

Gait and balance impairments in patients with subcortical vascular cognitive impairment

Subcortical vascular cognitive impairment (SVCI) is a subtype of vascular cognitive impairment associated with extensive cerebral small vessel diseases (CSVDs) imaging biomarkers. The objectives of this work w...

Authors: Mahmoud Ebrahim Mostafa Elhassanien, Yasser Abo Elfotoh El-Heneedy, Kareem Mohammed Ramadan, Mona Ahmed Kotait, Amr Elkholy, Mohammed Youssef Elhamrawy and Wafik Said Bahnasy

Guillain-Barre syndrome in 220 patients with COVID-19

This review summarises and discusses recent findings concerning the pathophysiology, clinical presentation, diagnosis, treatment, and outcome of SARS-CoV-2-associated Guillain-Barre syndrome (SC2-GBS). By the ...

Authors: Josef Finsterer and Fulvio A. Scorza

Prevalence of burnout among neurologists in Saudi Arabia

Burnout is a psychological syndrome defined as emotional exhaustion (EE), depersonalization (DP), and reduced personal accomplishment (PA) secondary to work stress. Burnout is widespread among medical workers....

Authors: Zina Ali Al-Qahtani and Adel Alhazzani

Decompressive laminectomy with instrumented posterolateral fusion for degenerative lumbar disease in elderly, is it safe and beneficial?

With improvement of health care in last decades, the age of general population increased. As the elderly with degenerative lumbar disease needs to remain physically active for more years, lumbar decompression ...

Authors: Ahmed A. Arab, Mohammed H. Eltantawy and Ashraf El-Desouky

Outcomes and issues of 12 chordomas treated in a single center

Chordomas stem from notochordal vestiges and rank as low-grade bone malignancies although fraught with high risk of recurrence. This study assesses the clinical outcomes of twelve chordoma cases treated in our...

Authors: Maria Karampouga, Fotis Tsetsos, Pavlos Sakellariou and Ioannis Baltas

Reliability and validity of Arabic version of the brief international cognitive assessment for multiple sclerosis: Egyptian dialect

Given the diversity of multiple sclerosis (MS) symptoms including cognitive impairment in certain domains, the need to develop a rapid and at the same time thorough tool for cognitive assessment is mandatory a...

Authors: Marwa Farghaly, Dawn W. Langdon, Nevin M. Shalaby, Hatem S. Shehata, Noha T. Abokrysha, Amr Hassan, Mohamed I. Hegazy, Alaa Elmazny, Sandra Ahmed, Shaimaa Shaheen, Alshaimaa S. Othman, Osama Yacoub and Nirmeen A. Kishk

Assessment of the outcome of percutaneous pedicle screws in management of degenerative and traumatic dorsal and lumbar pathologies

Percutaneous pedicle screw technique is relatively a recent technique that evolved the concept of posterior spinal instrumentation, utilizing familiar fluoroscopic landmarks to guide the procedure of screws in...

Authors: Ayman Hussein, Hamdy Ibrahim, Hazem Mashaly, Sameh Hefny and Abdelrahman El Gayar

Guillain-Barre syndrome after coronary artery bypass graft surgery: a case report and literature review

Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy, often preceded by an infection. Rarely, it is preceded by a surgical procedure. Most of the postsurgical GBS cases are reported with the neuros...

Authors: Sajid Hameed, Lubna Ashraf Jafri and Dureshahwar Kanwar

Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population

Elderly people with epilepsy are large, but neglected group. Data on the predictive factors for recurrent seizures in the elderly population are inconclusive or are not known for the majority of patients. This...

Authors: Steven Emil Gerges, Mahmoud Hemeda El Rakawy, Naglaa Mohammed El Khayat, Yousry Abo Elnaga Abdelhamid, Ahmed Mohammed Hazzou, Hossam Mohammed Shokri and Mona Mokthar Wahid El din

Impact of gender, depression severity and type of depressive episode on efficacy and safety of escitalopram: an observational study on major depressive disorder patients in southern India

Antidepressant response is a complex trait influenced by clinical, demographic and genetic factors.

Authors: Tatiyana Mandal, Laxminarayana Kurady Bairy, Podila Satya Venkata Narasimha Sharma and Vijaya Lakshmi Valaparla

Depression facilitators from the perspective of Iranian patients with major depressive disorder: a qualitative research

Major depressive disorder is the most common psychological disorder and affects many people worldwide. Therefore, it is important to identify the factors that cause or facilitate this disorder.

Authors: Milad Rezaiye, Moloud Radfar and Masumeh Hemmati MaslakPak

Motor unit number estimation versus compound muscle action potential in the evaluation of motor unit loss in amyotrophic lateral sclerosis

Motor neuron loss is the primary pathologic feature of amyotrophic lateral sclerosis (ALS). An estimate of the number of surviving motor units (MUs) represents a direct measure of the disease state in ALS. The...

Authors: Arwa Khalid Ibrahem, Akram Mohammed Al-Mahdawi and Farqad Bader Hamdan

Recurrent spontaneous CSF rhinorrhea: combined endo-nasal endoscopic repair with lumbo-peritoneal shunt insertion

Spontaneous cerebrospinal fluid (CSF) leaks are associated with high morbidity and recurrence rates. Most cases had increased intracranial pressure (ICP) on presentation. There is still controversy regarding t...

Authors: Ahmed Y. Soliman, Kamal Ebeid and Amr Abu Elfadle

Multiple sclerosis patients and COVID-19

Coronavirus disease 2019 (COVID-19) is now a major issue for all fields of medicine. Due to the higher mortality rate among patients with chronic diseases, it has also caused concern in patients with multiple ...

Authors: Hubert Mado and Monika Adamczyk-Sowa

Surgical outcome of primary intradural spinal arachnoid cysts: a series of 10 cases

Primary intradural spinal arachnoid cysts are rare pathologies of uncertain etiology and variable presentation from no symptoms to myelopathy or radiculopathy according to cord or root compression. MRI with di...

Authors: Essam Abdelhameed and Ahmed Ali Morsy

Role of some inflammatory biomarkers in prediction of short-term outcome in acute ischemic stroke

Several factors affect acute ischemic stroke (AIS) outcomes.

Authors: Yosria Abd Al Hameed AlTaweel, Rania Sanad Nageeb, Pakinam Mahmoud Metwally and Ahmed Elsayed Badawy

Serum level of brain-derived neurotrophic factor in patients with relapsing–remitting multiple sclerosis: a potential biomarker for disease activity

Brain-derived neurotrophic factor (BDNF) is secreted by immune cells in response to neuroimmune and inflammatory cascades as an act to prevent axonal and neuronal damage after various pathological insults. The...

Authors: Mohammed I. Oraby, Hatem A. El Masry, Sanaa S. Abd El Shafy and Esraa M. Abdul Galil

Frequency of peri-ictal apnea and cardiac arrhythmias in epileptic seizures

Available data from witnessed and monitored sudden unexpected death in epilepsy (SUDEP) cases postulate that ictal central apnea (ICA) and ictal arrhythmias are the main causes of SUDEP. ICA is a frequent semi...

Authors: Rady Yousif, M. Ossama Abdulghani, A. Gaber, Naglaa El Khayat, Y. A. Abo Elnaga and Mona Mokhtar Wahid El Din

Clinical predictors to cognitive impairment in multiple sclerosis patients

Cognitive dysfunction is increasingly recognized in multiple sclerosis, even in the early phase of the disease. Multiple sclerosis patients with even mild cognitive deficits may experience greater difficulties...

Authors: Haidy Elshebawy, Ebtesam Mohamed Fahmy, Nervana Mohamed Elfayoumy, Ahmed Mohamed Abdelalim and Rania Shehata Ismail

Assessment of cerebral hemodynamics in multiple sclerosis patients

Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. Autonomic dysfunction is present in a wide range of patients (15–80%) that might present with abnormalities in th...

Authors: Nouran M. Salah, Ahmed M. Elsadek, Lobna M. ELnabil, Ayman M. Nassef, Azza A. Abdelaziz and Mohamed A. Abdel Hafeez

MicroRNAs in central nervous system disorders: current advances in pathogenesis and treatment

MicroRNAs (miRNAs) are a class of short, non-coding, regulatory RNA molecules that function as post transcriptional regulators of gene expression. Altered expression of multiple miRNAs was found to be extensiv...

Authors: Mona Hussein and Rehab Magdy

Sequential approach of internal maxillary-to-middle cerebral artery bypass and endovascular occlusion for giant middle cerebral artery aneurysm: a case report

The combined approach to complex brain МСА aneurysm seems to be generally considered viable. Although it is fairly common, the combinations of modalities, which are suggested in different case reports, vary si...

Authors: Andrey Vladimirovich Sergeev, Alexander Viktorovich Savello, Vladislav Urievich Cherebillo, Aigazi Islamovich Kiskaev and Fatima Chemurzieva

Association of epileptiform brain activity and specific language impairment (SLI) in preschool children

Epileptiform activities can cause transient or permanent deficits that affect the children during development and may be accompanied by neurodevelopmental disorders like specific language impairment.

Authors: Ahmed Esmael, Sara Elsherbeny and Mohammed Abbas

High neutrophil-to-lymphocyte ratio predicts early neurological deterioration in spontaneous intracerebral hemorrhage patients

Intracerebral hemorrhage (ICH) is caused by bleeding, primarily into parenchymal brain tissue, and accounts for 9 to 27% of all strokes worldwide. Higher neutrophils, lower lymphocytes, and higher neutrophil-t...

Authors: Wafaa S. Mohamed, Amr E. Kamel, Ahmed H. Abdelwahab and Mohamed E. Mahdy

Depression and COVID-19 patients with chronic pain: practical considerations

Authors: A. Alcántara Montero, S. R. Pacheco de Vasconcelos and F. Peñato Tarifa