Articles

The potential value of capsaicin in modulating cognitive functions in a rat model of streptozotocin-induced Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder.

Authors: Manal A. Shalaby, Howaida A. Nounou and Maha M. Deif

Role of single nucleotide polymorphisms (SNPs) in common migraine

Single nucleotide polymorphisms (SNPs) may act as biological markers, as they can relate to the genes that are associated with various complex diseases such as heart diseases, diabetes, cancer, schizophrenia, ...

Authors: Sukhvinder Kaur, Arif Ali, Uzair Ahmad, Yaser Siahbalaei, A. K. Pandey and Balkirat Singh

Radiofrequency thermocoagulation in cases of atypical trigeminal neuralgia: a retrospective study

Trigeminal neuralgia (TN) is the most common cause of neuropathic facial pain. Atypical TN are usually refractory to conventional medical treatments and the standard microvascular decompression surgeries that ...

Authors: Mert Akbas, Haitham Hamdy Salem, Tamer Hussien Emara, Bora Dinc and Bilge Karsli

Post-stroke executive dysfunction and verbal fluency negatively correlated to IL8

Patients with acute ischemic stroke are at a higher risk of developing cognitive impairment which could be often attributed to cytokine activation.

Authors: Hala A. Shaheen, Lamiaa I. Daker, Mohammed M. Abbass and Asmaa A. Abd El Fattah

Music therapy as a therapeutic tool in improving the social skills of autistic children

The Cochrane Collection reviews of randomized clinical trials (RCT) showed a favorable result of music therapy (MT) on individuals with autism spectrum disorder (ASD) compared with a placebo treatment.

Authors: Geetha Bharathi, Anila Venugopal and Balachandar Vellingiri

Effect of valproate versus levetiracetam monotherapy on reproductive functions in newly diagnosed epileptic males

Antiepileptic drugs are responsible for reproductive dysfunction in male epileptic patients.

Authors: Wafaa S. Mohamed, Rania S. Nageeb, Noha A. Hashim and Alaa A. Omran

Unusual neurosurgical emergency in Paget’s disease of the skull: a case report and review of the literature

Paget’s disease of bone is usually asymptomatic in most cases. The neurosurgeon should be familiar with the common presentation and complications. The rare presentation of this case of Paget’s disease of the s...

Authors: Ahmed Hamdy Ashry, Dina Mahmoud Alnajjar, Amr Abdelmonam Abdelaziz Mostafa Elkatatny and Mohamed Ahmed Eissa

Relative frequency and prognosis of vascular aphasia (follow-up at 3 months) in the Neurology Department of Assiut University Hospital

Post-stroke aphasia (PSA) is a disabling complication after stroke leading to impairment of quality of life. It was reported to develop in one third of patients with stroke and in two thirds of patients with r...

Authors: Hamdy Naguib El-Tallawy, Adel Hassanein El Sayed Gad, Anwar Mohamed Ali and Manar Nasr Abd-El-Hakim

Influence of percentage of body-weight support on gait in patients with traumatic incomplete spinal cord injury

Body-weight-supported treadmill training (BWSTT) is a treatment method to help patients with incomplete spinal cord injuries to restore the capability to walk again.

Authors: Moataz M. El Semary and Lamiaa I. Daker

Sex differences among epileptic patients: a comparison of epilepsy and its impacts on demographic features, clinical characteristics, and management patterns in a tertiary care hospital in Egypt

Epilepsy is one of the most common neurological conditions. We aimed to identify sex differences in the demographic, clinical features, and treatment strategies in epileptic patients.

Authors: Nirmeen Kishk, Husam Mourad, Sahar Ibrahim, Reham Shamloul, Aiman Al-Azazi and Nevin Shalaby

Do core stability exercises improve upper limb function in chronic stroke patients?

Upper limb paresis is a common problem in patients with stroke.

Authors: H. El-Nashar, A. ElWishy, H. Helmy and R. El-Rwainy

Tumor necrosis factor alpha in peripheral neuropathy in type 2 diabetes mellitus

To compare serum levels of tumor necrosis factor alpha (TNF-α) between type 2 diabetes mellitus patients with and without peripheral neuropathy (PN). Also, to study the relation between peripheral nerves condu...

Authors: Wafik M. El Sheikh, Ibrahim E. Alahmar, Gelan M. Salem and Mohamed A. El-Sheikh

Probable Creutzfeldt-Jakob disease—a case report at Suez Canal University Hospital, Egypt

Among transmissible spongiform encephalopathies, Creuzfeldt-Jakob disease is considered a rare neurodegenerative disorder. The clinical features include rapid progressive dementia and myoclonic jerks, which pr...

Authors: Mohamed Negm and Ehab Hashish

Relationship between periodic limb movement and seizure recurrence in genetic generalized epilepsy

Although periodic limb movements are prevalent among patients with epilepsy, the exact relationship between these movements and epilepsy remains elusive.

Authors: Mohamed Mohamed Hamdy, Amr Mohamed Elfatatry, Jaidaa Farouq Mekky and Eman Hamdy

Could vitamin D deficiency have an impact on motor and cognitive function in Parkinson’s disease?

Multiple epidemiological data showed a significant higher prevalence of hypovitaminosis D in patients with Parkinson’s disease (PD).

Authors: Rasha H. Soliman, Mohammed I. Oraby, Mona Hussein, Sanaa Abd El-Shafy and Sara Mostafa

Cognitive assessment of idiopathic intracranial hypertension patients

Idiopathic intracranial hypertension (IIH) is a disorder of unknown etiology. Goals of treatment are to preserve vision and alleviate symptoms, including intractable headache, pulsatile tinnitus, and nausea. C...

Authors: Iman A. Elbanhawy, Gihan M. Ramzy, Amal S. Ashour and Diana M. Khedr

Cerebrovascular reactivity recovery following carotid angioplasty and stenting

Internal carotid artery high-grade stenosis is a major cause of stroke. Carotid angioplasty and stenting (CAS) is a reasonable approach for treatment of certain patients. Cerebrovascular reactivity (CVR) evalu...

Authors: Saher El-Sayed Hashem, Ehab Shaker Belal, Montaser Moawad Hegazy, Ahmed Ali El-Bassiony, Sandra Mohamed Ahmed and Islam I. Zaid

Public knowledge of warning signs and risk factors of cerebro-vascular stroke in Ismailia Governorate, Egypt

Knowledge and awareness of cerebro-vascular stroke (CVS) warning symptoms and risk factors is deficient in the general population in the developing countries.

Authors: Ahmed Osama, Yossri Ashour, Reda Abd El-Razek and Ibrahim Mostafa

Repetitive TMS in treatment of resistant diabetic neuropathic pain

Diabetes mellitus is a clinical syndrome characterized by hyperglycemia caused by respective or absolute deficiency of insulin. Painful neuropathy in diabetic population is popular, impacting numerous chronic ...

Authors: Ann A. Abdelkader, Amira M. El Gohary, Husam S. Mourad and Dina A. El Salmawy

Prevalence of Alzheimer dementia in Upper Egypt (desert areas)

Alzheimer’s disease (AD) is the commonest type of Dementia worldwide. It rapidly increases with aging especially over 70 years.

Authors: Hamdy N. A. EL Tallawy, Wafaa M. A. Farghaly, Mohamed Abd El Hamed, Reda Badry, Khaled Usama, Ghaydaa A. Shehata, Amal M. Tohamy, Khaled O. Abdulghani, Mostafa K. Ghanem, Mohamed A. Sayed, Ahmed H. Yousef, Heba S. Hashem and Tarek A. Rageh

Refractory epilepsy and obstructive sleep apnea: is there an association?

A high prevalence of obstructive sleep apnea (OSA) has been reported in medically refractory epilepsy patients, and there is increasing evidence that treatment of OSA in refractory epilepsy patients would redu...

Authors: Hebatallah R. Rashed, Mohamad A. Tork, Lobna M. El-Nabil, Naglaa M. El-Khayat, Nahed S. Ahmed, Salem T. Abdelhady, Khaled O. Abdulghani and M. Ossama Abdulghani

Comment to “Diabetic peripheral neuropathy: the potential role of vitamin D deficiency” by Oraby et al.

Authors: Marco Baldrighi and Gian Carlo Avanzi

Neuro-ophthalmological biomarkers of visual outcome in newly diagnosed idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a disorder of unidentified etiology characterized by raised intracranial pressure (ICP) without clinical, laboratory, or radiological evidence of intracranial path...

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Mahmoud Ebrahim Mostafa Elhassanien, Amr Fawzy Sharaf and Hagar Ahmed Khalid

Decompressive craniectomy in malignant hemispheric infarction: favorable outcome and disability

Patients with malignant middle cerebral artery (MCA) infarction are prone to a mortality rate of 70–80%. Decompressive craniectomy (DC) has been used as an important treatment modality to control refractory in...

Authors: Ahmed Elsayed and Adham Elsayed

Non-motor symptoms in newly diagnosed Parkinson’s disease patients

The non-motor symptoms (NMSs) in Parkinson’s disease (PD) patients have greater effects on their quality of life compared to the motor symptoms; however, they are under-recognized.

Authors: Osama A. Ragab, Yasser A. Elheneedy and Wafik S. Bahnasy

Role of superficial peroneal sensory potential and high-resolution ultrasonography in confirmation of common peroneal mononeuropathy at the fibular neck

Common peroneal mononeuropathy at the fibular neck (CPN) is one of the most frequent neuropathies of the lower extremities. Nerve conduction studies (NCS) have been used to confirm the diagnosis of CPN and loc...

Authors: Rania S. Nageeb, Wafaa S. Mohamed, Ghada S. Nageeb, Eman Al Desoky and Taghreed M. Azmy

Post-bariatric surgery peripheral neuropathies: Kuwaiti experience

Obesity is a major global health problem. Kuwait has a very high prevalence of obesity, and consequently, the number of bariatric surgeries is rising.

Authors: Hanaa M. Rashad, Doaa Youssry, Dina F. Mansour, Ayman Kilany, Jasem Y. Al-Hashel, Adnan J. Khuraibet, Walaa A. Kamel and Rossen T. Rousseff

The NIHSS score can predict the outcome of patients with primary intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is characterized to be the most lethal form of stroke, with high rates of mortality, not only during the acute phase (39%), but also 3 months later (33.5%) with a significant lon...

Authors: Mohammed Elsayed Mahdy, Nesma Abdelmonem Ghonimi, Tamer Sabry Elserafy and Wael Mahmoud

Prevalence of migraine in Upper Egypt

Migraine is a significant health problem due its frequency and accompanying morbidity.

Authors: Hamdy N. El-Tallawy, Wafaa M. Farghaly, Mohamed A. Abdelhamed, Reda Badry, Tarek A. Rageh, Wael T. Soliman, Khaled O. Abdulghani, Mahmoud Hassan, Sayed Sobhy and Ghaydaa A. Shehata

Ankle-brachial index in ischemic stroke: risk factor correlation and prognostic value

Ankle-brachial index (ABI) is not only a marker of lower limb peripheral arterial disease (PAD), but may also reflect the severity of systemic atherosclerosis.

Authors: H. Afify, S. Noshy, A. Gaber and T. Kamel

Vitamin D status in acute ischemic stroke: relation to initial severity and short-term outcome

A growing body of evidence indicated that vitamin D has a potential protective role against neurovascular injury. Low serum vitamin D has been associated with increased risk for incident stroke and stroke fata...

Authors: E. Fahmy, S. Sharaf, H. Helmy and S. Sherif

Assessment of the risk factors and functional outcome of delirium in acute stroke

Post stroke delirium is a multifactorial life-threatening process, still poorly understood. The aim of the study was to identify the risk factors associated with the development of delirium in acute stroke pat...

Authors: A. M. Zaitoun, Dorriya Abdel Fattah Elsayed, Bothina M. Ramadan and Hanan Ahmed Abdel Gaffar

Psychiatric and sleep abnormalities in school-age children with migraine

Migraine is a primary headache that commonly starts in childhood and adolescent’s periods with great negative impacts on the educational and psychosocial performances of its sufferers. The objectives of this w...

Authors: Yasser Abo Elfotoh El-Heneedy, Wafik Said Bahnasy, Shereen Ahmed ELAhwal, Reham Abdel Rahman Amer, Shereen Desoky Ahmed Abohammar and Heba Ahmed Mohamed Salem

Role of dynamic sonography in ulnar nerve entrapment at elbow

High-resolution ultrasound (HRUS) is a rapidly developing technology that is gaining popularity for the evaluation of the ulnar nerve.

Authors: H. Al-Azizi, M. Mosaad, S. Yahia, H. Helmy and A. Kersh

Role of aspirin discontinuation in recurrence of ischemic cerebrovascular stroke

Discontinuation of aspirin was suggested to be a risk factor for recurrent ischemic stroke; however, it was underestimated by most physicians.

Authors: Mohamed Negm and Reda Abd El-Razek

Comparison between intracranial collaterals and cerebral hemodynamics in patients with extracranial carotid stenosis versus combined extra- and intracranial stenosis using transcranial duplex

In acute ischemic stroke, collateral circulation plays an important role in maintaining blood flow to the tissue that is at risk of progressing into ischemia, and in increasing the successful recanalization ra...

Authors: Sara Hamdy, Hani Mohamed Amin Aref, Ramez Reda and Ahmed ElSadek

Fixation of multiple level anterior cervical disc using cages versus cages and plating

Cervical disc herniation is a common cause of neck, upper limb, and upper back pain. In severe cases, neurological deficit might occur. It is surgically treated anteriorly or posteriorly, anteriorly through bo...

Authors: Ahmed Elsayed and Sameh Sakr

Risk factors for post-stroke depression in Sohag University Hospital

Depression is one of the important complications of stroke. Post-stroke depression is associated with more physical disability, especially in daily activities, poor functional outcome, and high mortality rate.

Authors: Gharib Fawi Mohammed, Hemaid Mostafa Azab, Mohamed Abd-Elmoneim Sayed, Hassan Mohammed Elnady, Hanan Youssif and Ossama Abd-Alreheem Mahmoud

Diabetic peripheral neuropathy: the potential role of vitamin D deficiency

Vitamin D is well known for its role in promoting calcium and phosphorus absorption and is recently associated with various neurological disorders.

Authors: Mohammed I. Oraby, Mona Abu Srie, Sanaa Abdelshafy and Eman Elfar

Experience in the management of post-operative spinal infection

Post spinal surgery infection is not uncommon. It is considered as one of the most annoying complication following surgery on the spine. The major burdens of post spinal surgery infection are time and money co...

Authors: Mohamed A. Eshra

Role of minimal hepatic encephalopathy in road traffic accidents

The term minimal hepatic encephalopathy (MHE) is defined as encephalopathy that does not lead to clinically overt cognitive dysfunction but can have an impact on quality of life, risk of involvement in road tr...

Authors: Mohammad Mohai El-Din Awad, Abd-El Raouf Mohamed El-Deib, Fadia Mostafa Attia, Mohamed Negm, Mohamed Hassan Mohamed Soliman and Wafaa Hassan Omar

Assessment of postural balance in multiple sclerosis patients

Disturbance of balance and falls are commonly observed in people with multiple sclerosis (MS).

Authors: Abdulalim Atteya, Abeer Elwishy, Nirmeen Kishk, Rania Shehata Ismail and Rania Badawy

Assessment of carotid intima-media thickness and carotid plaque formation among patients with ischemic stroke and hepatitis C virus infection

Cerebrovascular diseases are well known all over the world to be among the top list of the causes of death. One third of ischemic stroke could be regarded to plaque rupture and embolization. The actual mechani...

Authors: Ahmed Osama, Yossri Ashour, Reda Abd El-Razek and Dina Monir

Circadian and circannual patterns of stroke

Cerebrovascular event peaks occur in the morning (≈ 9:00 am) with another one peak in the evening (≈ 8:00 pm) and a trough at night. Knowledge about circadian influences on mechanisms involved in cerebrovascul...

Authors: Shereen A. Al-Ahwal, Osama A. Ragab, Ashraf A. Abo Elsafa and Azza A. Ghali

The mean platelet volume and plateletcrit as predictors of short-term outcome of acute ischemic stroke

Activation of the platelet plays an important role in the process of atherosclerosis. Mean platelet volume (MPV) is significantly associated with the poor outcome of acute ischemic stroke while the results of ...

Authors: Al-Amir Bassiouny Mohamed, Hassan Mohamed Elnady, Hazem Kamal Alhewaig, Hesham Moslem Hefny and Ashraf Khodery

Vasospasm following aneurysmal subarachnoid hemorrhage: prediction, detection, and intervention

Vasospasm of the cerebral blood vessels is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) which results in delayed cerebral ischemia (DCI) and worsening of the outcome.

Authors: Hassan Gamal Eldeen Nassar, Azza Abbas Ghali, Wafik Said Bahnasy and Mostafa Mohamed Elawady

Microemboli versus hypoperfusion as an etiology of acute ischemic stroke in Egyptian patients with watershed zone infarction

Brain perfusion is most likely to be impaired in border zone regions, and clearance of emboli will be most impaired in these regions of least blood flow. Severe occlusive disease of the internal carotid artery...

Authors: Ahmed ElSadek, Ahmed Gaber, Hossam Afifi, Sherin Farag and Nouran Salaheldien

Use of low-power He-Ne laser therapy to accelerate regeneration processes of injured sciatic nerve in rabbit

Photostimulation using low-power laser had been used for nervous repair with interesting results. This study aimed to evaluate the influence of 20 mW low-power He-Ne laser on the regeneration of a peripheral s...

Authors: Ahmed Majeed Al-Shammari, Yahya Syhood and Ahmed S. Al-Khafaji

Anxiety, depression, and quality of life in backache patients before and after spinal traction

Chronic pain has a negative impact on quality of life and psychological well-being. The objectives of this study are to investigate the psychological status and quality of life in backache patients before and ...

Authors: Amr Said Shalaby, Dina Rifaat el-sharaki and Gelan Mahmoud Salem

Brain magnetic resonance spectroscopy and cognitive impairment in chronic hepatitis C patients

Cognitive dysfunction in patients with chronic hepatitis C virus (HCV) infection may appear long before the development of severe liver cirrhosis. These alterations are not ascribed to hepatic encephalopathy; ...

Authors: Ahmed Abo Hagar, Youssri Ashour, Mohamed Negm, Mohamed Abdelfatah, Khaled A. Gad and Ehab Hashish