Articles

Circadian and circannual patterns of stroke

Cerebrovascular event peaks occur in the morning (≈ 9:00 am) with another one peak in the evening (≈ 8:00 pm) and a trough at night. Knowledge about circadian influences on mechanisms involved in cerebrovascul...

Authors: Shereen A. Al-Ahwal, Osama A. Ragab, Ashraf A. Abo Elsafa and Azza A. Ghali

The mean platelet volume and plateletcrit as predictors of short-term outcome of acute ischemic stroke

Activation of the platelet plays an important role in the process of atherosclerosis. Mean platelet volume (MPV) is significantly associated with the poor outcome of acute ischemic stroke while the results of ...

Authors: Al-Amir Bassiouny Mohamed, Hassan Mohamed Elnady, Hazem Kamal Alhewaig, Hesham Moslem Hefny and Ashraf Khodery

Vasospasm following aneurysmal subarachnoid hemorrhage: prediction, detection, and intervention

Vasospasm of the cerebral blood vessels is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) which results in delayed cerebral ischemia (DCI) and worsening of the outcome.

Authors: Hassan Gamal Eldeen Nassar, Azza Abbas Ghali, Wafik Said Bahnasy and Mostafa Mohamed Elawady

Microemboli versus hypoperfusion as an etiology of acute ischemic stroke in Egyptian patients with watershed zone infarction

Brain perfusion is most likely to be impaired in border zone regions, and clearance of emboli will be most impaired in these regions of least blood flow. Severe occlusive disease of the internal carotid artery...

Authors: Ahmed ElSadek, Ahmed Gaber, Hossam Afifi, Sherin Farag and Nouran Salaheldien

Use of low-power He-Ne laser therapy to accelerate regeneration processes of injured sciatic nerve in rabbit

Photostimulation using low-power laser had been used for nervous repair with interesting results. This study aimed to evaluate the influence of 20 mW low-power He-Ne laser on the regeneration of a peripheral s...

Authors: Ahmed Majeed Al-Shammari, Yahya Syhood and Ahmed S. Al-Khafaji

Anxiety, depression, and quality of life in backache patients before and after spinal traction

Chronic pain has a negative impact on quality of life and psychological well-being. The objectives of this study are to investigate the psychological status and quality of life in backache patients before and ...

Authors: Amr Said Shalaby, Dina Rifaat el-sharaki and Gelan Mahmoud Salem

Brain magnetic resonance spectroscopy and cognitive impairment in chronic hepatitis C patients

Cognitive dysfunction in patients with chronic hepatitis C virus (HCV) infection may appear long before the development of severe liver cirrhosis. These alterations are not ascribed to hepatic encephalopathy; ...

Authors: Ahmed Abo Hagar, Youssri Ashour, Mohamed Negm, Mohamed Abdelfatah, Khaled A. Gad and Ehab Hashish

Insulin-Like Growth Factor-1 in Acute Ischemic Stroke

Cerebrovascular ischemic stroke is highly prevalent in the general population and is considered one of the frequent causes of mortality and disability. Insulin-like growth factor-1 (IGF-1) is recognized as an ...

Authors: Hala Shaheen, Sayed Sobhy, Sherine El Mously, Manal Niazi and Mohammed Gomaa

Relevance of Helicobacter pylori infection in Egyptian multiple sclerosis patients

Multiple sclerosis (MS) is an autoimmune demyelinating disorder. The etiology of MS remains unknown exactly. Helicobacter pylori heat shock proteins were suggested as a potential trigger of immune system causing ...

Authors: Steven Emil Gerges, Taha Kamel Alosh, Salma Hamed Khalil and Mona Mokhtar Waheed El Din

Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials

Central post-stroke pain (CPSP) is an under-recognized complication of stroke although it can lead to deterioration in quality of life and impairment in activities of daily living. Its estimated prevalence var...

Authors: Ahmed Osama, Ahmed Abo Hagar, Saly Elkholy, Mohamed Negm, Reda Abd El-Razek and Marwa Orabi

Investigating the influence of ubiquinone blood level on the abilities of children with specific learning disorder

Ubiquinone has antioxidant properties and has been linked to cognitive performance in some neuropsychiatric disorders. Its role in specific learning disorder manifestations has not been previously investigated...

Authors: Ehab Ragaa Abdelraouf, Ayman Kilany, Adel F. Hashish, Ola Hosny Gebril, Suzette Ibrahim Helal, Haytham Mohamad Hasan and Neveen Hassan Nashaat

Sympathetic skin response in patients with systemic sclerosis and rheumatoid arthritis

Sympathetic skin response (SSR) is a technique to assess the sympathetic cholinergic pathways. Sympathetic dysfunction may participate in the development of pain, which is the major complaint in patients with ...

Authors: Reda Badry, Rania M. Gamal, Manal M. Hassanien, Mohamed Abd El Hamed, Nevin Hammam and Bastawy M. El Fawal

Carnitine deficiency in epileptic children treated with a diversity of anti-epileptic regimens

Carnitine deficiency is relatively common in epileptic patients. The risk factors reported include the combination of valproic acid with other antiepileptic drugs (AEDs), young age, multiple neurologic disabil...

Authors: Sherine El Mously, Hadeer Abdel Ghaffar, Remon Magdy, Somaia Hamza and Mohamed Mansour

Serum 25(OH) vitamin D level and its relation to diabetic peripheral neuropathy in Egyptian patients with type 2 diabetes mellitus

Some clinical studies demonstrated a significant association between vitamin D deficiency and diabetic peripheral neuropathy (DPN).

Authors: Seham E. Abdelsadek, Entesar O. El Saghier and Sabah I. Abdel Raheem

Event-related evoked potential versus clinical tests in assessment of subclinical cognitive impairment in chronic hepatitis C virus

Chronic infection by hepatitis C virus causes impairment in neurocognitive function in up to 50% of patients which may not be detected by clinical tests.

Authors: Hanaa Khalaf Fath-Elbab, Elham Ahmed, Dina Fathy Mansour and Wail Talaat Soliman

Prevalence of childhood and adolescence epilepsy in Upper Egypt (desert areas)

A high prevalence of epilepsy in children is frequently found in developing countries.

Authors: Wafaa M. Farghaly, Mohamed A. Abd Elhamed, Enas M. Hassan, Wael T. Soliman, Mohamed A. Yhia and Nermin A. Hamdy

Endovascular coiling for cerebral aneurysm: single-center experience in Egypt

Endovascular management for cerebral saccular aneurysm has evolved in the last decade with evolution in both equipment and material. Coiling is still the mainstay of cerebral aneurysm endovascular management. ...

Authors: Mohamed Khaled Elewa

Effect of transcranial direct current stimulation on cognitive function in stroke patients

Cognitive impairment after stroke is common and can cause disability with major impacts on quality of life and independence. Transcranial direct current stimulation may represent a promising tool for reconstit...

Authors: Hussien Ahmed Shaker, Salah Abd Elmonem Sawan, Ebtesam Mohamed Fahmy, Rania Shehata Ismail and Shymaa Abd Elhamid Abd Elrahman

Quantitative evaluation of shoulder proprioception 6 months following stroke

Chronic shoulder pain following cerebrovascular stroke (CVS) is a major problem that persists after maximum recovery of motor functions. Such pain has been attributed to altered shoulder joint kinematics causi...

Authors: Moshera Hassan Darwish, Sandra Ahmed, Ahmed Abdelalim and Abdelaziz Abdelaziz Elsherif

Evaluating sex hormones and cytokine profile in Egyptian females with relapsing-remitting multiple sclerosis

Sexual dimorphism shown in multiple sclerosis suggests an interaction between immune system and sex hormones. The objective of this study is to determine the hormonal profile and serum cytokine levels in Egypt...

Authors: Forayssa M. Talaat, Noha T. Abokrysha, Dalia M. Labib, Engy El Khateeb and Ghada Hatem Abd El Aziz

The role of muscle ultrasound in helping the clinical diagnosis of muscle diseases

Selective involvement of certain muscles is an indicator for muscle diseases and helps to direct the diagnosis, but in some cases, it cannot be detected clinically; hence, the roles of muscle MRI and ultrasoun...

Authors: Hanan Helmy, Ahmed Aboumousa, Asmaa Abdelmagied, Aya Alsayyad and Sandra Ahmed Nasr

Evaluation of dysphagia in different phenotypes of early and idiopathic Parkinsonism

Parkinsonism (PD) is a common neurodegenerative disorders into which dysphagia occurs mainly in the late stage and to a lesser extent in an early stage. Diagnosis of dysphagia particularly in early idiopathic ...

Authors: Al-Amir Bassiouny Mohamed, Gharib Fawi Mohamed, Hassan Mohamed Elnady, Mohamed Abdelmoneim Sayed, Ahmed Mamdouh Imam, Megahed Mohamed Hassan and Sherihan Rezk Ahmed

Mean platelet volume to platelet count ratio as a laboratory indicator of mortality in pneumonia following ischemic stroke

Platelets have a vital role in antimicrobial host defenses. The objective of this study was to evaluate if increased mean platelet volume to platelet count (MPV/PC) ratio in acute ischemic stroke patients comp...

Authors: Rania S. Nageeb, Mohammed M. N. Abozaid, Ghada S. Nageeb and Alaa A. Omran

The relationship between the severity of disability and serum IL-8 in acute ischemic stroke patients

Stroke is the third leading cause of death and leading cause of adult disability worldwide. Long-term disability is a significant problem among survivors; post-stroke inflammation is well known to contribute t...

Authors: Hala A. Shaheen, Lamiaa I. Daker, Mohammed M. Abbass and Asmaa A. Abd El Fattah

Serum insulin-like growth factor 1 (IGF-1) in multiple sclerosis: relation to cognitive impairment and fatigue

Multiple sclerosis (MS) is a chronic demyelinating central nervous system (CNS) disease. Changes in insulin growth factor 1 (IGF-1) input to the brain can affect survival of myelin and CNS cells. The study aim...

Authors: Rania S. Nageeb, Noha A. Hashim and Amal Fawzy

Relation between migraine pattern and white matter hyperintensities in brain magnetic resonance imaging

Migraine is a common disorder in general population. Presence of white matter hyperintensities (WMHs) in brain MRI of migraine patients was not studied clearly. Detection of the prevalence of white matter hype...

Authors: Mohamed Negm, Ahmed Mohamed Housseini, Mohamed Abdelfatah and Alshimaa Asran

Sleep disturbances in diabetic peripheral neuropathy patients: a clinical and polysomnographic study

Disordered sleep breathing is a common complication of diabetic peripheral neuropathy (DPN) manifested by excessive daytime sleepiness, morning headache, morning dizziness, cognitive decline, and mood changes.

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Ehab Ahmed Shawky El-Seidy, Nema Ata Allah Labib and Ibrahim Salah Eldeen Ibrahim

Cortisol level and suicidal risk

Authors: Beuy Joob and Viroj Wiwanitkit

Early predictors of conversion in patients with clinically isolated syndrome: a preliminary Egyptian study

Clinically isolated syndrome (CIS) is the first neurologic episode of multiple sclerosis (MS). Clinical presentation, neurophysiological studies, and magnetic resonance imaging (MRI) are used to predict risk o...

Authors: Hala A. Shaheen, Sayed S. Sayed, Lamiaa I. Daker and Mohamed A. Taha

Polysomnography, brain volumetry, and mismatch negativity as early biomarkers of amnestic mild cognitive impairment progression

Mild cognitive impairment (MCI) is a heterogenous disorder in which a proportion of patients follow stationary or regressive courses while others undergo clinical progression to dementia.

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Osama Abd Allah Ragab, Marwa Yassin Badr, Mohammad Abdel-Hakeem Seleem, Reham Abdel Rahman Amer, Rasha Ahmed El-Shafey and Mona Ahmed Kotait

Primary monosymptomatic nocturnal enuresis: an etiological study

Nocturnal enuresis (NE) is a very common chronic pediatric problem with bad psychological consequences.

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Ehab Ahmed Shawky El-Seidy, Ibrahim Salah Eldeen Ibrahim, Mohammad Abdel-Hakeem Seleem and Amira Youssef Ahmed

Predictors of stroke outcome: the role of hemorheology, natural anticoagulants, and serum albumin

The early hours after an acute stroke are crucial; early accurate prediction of outcome in stroke patients can help health system providers and families to choose appropriate lines of management and plan for t...

Authors: Saher S. Hashem, Sadek M. Helmy, Nervana M. El-Fayomy, Mohammed I. Oraby, Mohammed Menshawy, Nermin A. Dawood and Heba S. Hashem

Insomnia among non-depressed multiple sclerosis patients: a cross-sectional study

Insomnia is a common problem that affects approximately 50% of patients with multiple sclerosis (MS), who suffer from sleep disturbances. In general, persons with insomnia are at a higher risk of developing de...

Authors: A. A. Alhazzani, A. Alshahrani, M. Alqahtani, R. Alamri, R. Alqahtani, M. Alqahtani and M. Alahmarii

Quantitative electroencephalographic changes and hippocampal atrophy in diabetic patients with mild cognitive impairment in Ismailia region

Cognitive decline could start or get worse among elderly patients with diabetes mellitus more than elderly without diabetes mellitus. So, those diabetic elderly patients have more risk to develop Alzheimer’s d...

Authors: Ahmed Abo hagar, Yossri Ashour, Reda Abd El-Razek, Mohamed Elsamahy and Osama Shehab

STAT4 gene polymorphism in two major autoimmune diseases (multiple sclerosis and juvenile onset systemic lupus erythematosus) and its relation to disease severity

Multiple sclerosis (MS) and systemic lupus erythematosus (SLE) are chronic autoimmune mediated diseases with strong genetic and environmental components. The aim of this study is to evaluate the association of...

Authors: Rania S. Nageeb, Alaa A. Omran, Ghada S. Nageeb, Manal A. Yousef, Yassir A. A. Mohammad and Amal Fawzy

Spinal meningeal melanocytoma in a 5-year-old child: a case report and review of literature

Meningeal melanocytoma is considered a rare lesion arising from leptomeningeal melanocytes. Nearly two thirds of meningeal melanocytomas were reported in the intracranial compartment and the remaining one thir...

Authors: Ahmed M. Salah El-Din, Hashem M. Aboul-Ela, Mohamed F. Alsawy, Ahmed Koheil and Ahmed H. Ashry

Body mass index and vitamin D level in carpal tunnel syndrome patients

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity. The aim of this study is to evaluate the body mass index (BMI) and vitamin D levels in CTS patients.

Authors: Rania S. Nageeb, Nahed Shehta, Ghada S. Nageeb and Alaa A. Omran

Cerebral arteriovenous malformations in the era of embolization for angiographic cure: a single-center experience in Egypt

Embolization for cerebral arteriovenous malformations (AVMs) has evolved in the last decade with evolution in both equipment and material. Embolization targets have expanded to include angiographic cure.

Authors: Mohamed K Elewa

Predictors of shunt-dependent hydrocephalus following aneurysmal subarachnoid hemorrhage: a pilot study in a single Egyptian institute

Acute hydrocephalus can cause neurological deterioration after aneurysmal subarachnoid hemorrhage (aSAH). Predicting which patient would require shunting is challenging.

Authors: Hashem M. Aboul-Ela, Ahmed M. Salah El-Din, Ahmed A. Zaater, Mohamed Shehab and Ossama A. El Shahawy

Evaluation of bone health among epileptic patients using biochemical markers and DEXA scan: an Egyptian study

An association between antiepileptic drugs, low bone mineral density (BMD), fractures, and abnormalities in bone metabolism has been suggested for a longer period, although conclusive evidence has not been rep...

Authors: Ebtesam Mohamed Fahmy, Laila Ahmed Rashed, Rania Shehata Ismail, Hanan Helmy and Doaa Atef Mekkawy

Long-term follow-up of motor function deterioration following microsurgical resection of middle third parasagittal and falx meningioma

Incidence of parasagittal meningioma varies in literature; it ranges from 16.8% to 25.6% of intracranial meningioma. Parafalcine meningioma accounts for about 8.5% of intracranial meningioma. Based on their re...

Authors: Ashraf Ahmad Elzarief and Mohamed Fouad Ibrahim

Risk factors of acute ischemic stroke in patients presented to Beni-Suef University Hospital: prevalence and relation to stroke severity at presentation

Acute ischemic stroke is one of the major causes of disability and death worldwide. Effective prevention remains the best approach for reducing the burden of stroke. The aim of this work was to study the preva...

Authors: Rasha H. Soliman, Mohammed I. Oraby, Mohammed Fathy and Alaa M. Essam

Neurophysiologic tests screening cognitive impairment in idiopathic intracranial hypertension patients

Idiopathic intracranial hypertension (IIH) is a disorder with increased intracranial pressure of obscure cause. Patients with IIH may suffer from difficulty in thinking or concentrating. This work aimed at hig...

Authors: Iman A. Elbanhawy, Gihan M. Ramzy, Mye A. Basheer and Diana M. Khedr

Cerebral border zone infarction: an etiological study

Border zone infarcts (BZI) are ischemic lesions at the junction between two main arterial territories which may be either cortical or internal BZI.

Authors: Tarek Mohammed El-Gammal, Wafik Said Bahnasy, Osama Abd Allah Ragab and Ayman Mohammed AL-Malt

Sleep and psychiatric abnormalities in Gullian Barré Syndrome

The sensori-motor manifestations of Guillain Barré Syndrome (GBS) are usually severe enough to mask the psychiatric and sleep problems which are in need for more attention for better functional outcome.

Authors: Wafik Said Bahnasy, Yasser Abo Elfotoh El-Heneedy, Ahmed Mohamed El-Shamy, Marwa Yassin Badr, Reham Ahmed Amer and Ibrahim Salah Eldeen Ibrahim

Correlative study between C-reactive protein, clinical severity, and nerve conduction studies in Guillain-Barrè syndrome

Guillain-Barre' syndrome (GBS) is a serious autoimmune disorder in which the immune system attacks healthy nerve cells of the peripheral nervous system causing polyradiculoneuropathy which leads to weakness, n...

Authors: Yosria A. Altaweel, Sawsan Abdelaziz, Hala A. Fathy and Shimaa AbdelBadea

Surgical outcomes and predictors of complication in elderly patients with meningiomas

Surgical management of symptomatic meningioma in elderly is still a high-risk surgery due to increased incidence of complication rate. Many scoring systems have been proposed to expect the surgical risk and th...

Authors: Ayman E. Galhom, A. A. Madawi and M. M. Ellabban

Role of concentric needle Single Fiber Electromyography in detection of subclinical motor involvement in carpal tunnel syndrome

Conventional motor nerve conduction studies are usually normal in early and mild carpal tunnel syndrome (CTS). Single-fiber electromyography (SFEMG) measures the mean consecutive difference (MCD) as an express...

Authors: Aliaa A. Tawfeek, Amani M. Nawito, Radwa M. Azmy, Amr Hassan, Lamia M. Afifi and Saly H. Elkholy

Announcing the new launch of The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Authors: M. Ossama Abdulghani, Ahmed M. Abdelalim and Khaled O. Abdulghani