Articles

Quantitative motor unit potential analysis and nerve conduction studies for detection of subclinical peripheral nerve dysfunction in patients with compensated liver cirrhosis

Peripheral neuropathy is an underestimated problem of compensated liver cirrhosis despite its negative effect on quality of life. The aim was to assess the role of meticulous electrophysiological screening (ne...

Authors: Mostafa M. Elkholy and Ragaey A. Eid

Cluster seizures and status epilepticus in new onset seizures among adult Egyptians

New onset seizure (NOS) is defined as the first seizure within a 24-h period ever experienced by the patient. Cluster seizures (CS) or status epilepticus (SE) can be the first manifestation of epilepsy or it m...

Authors: Mahmoud Hemeida Mahmoud, Eman Mahmoud Awad, Ahmed Khalil Mohamed and Mohamed Ahmed Shafik

Is SARS-CoV-2 responsible for relapses of Parkinson’s disease?

Authors: Fulvio A. Scorza, Josef Finsterer and Ana C. Fiorini

Diagnostic value of brain MR imaging and its correlation with clinical presentation and cognitive functions in idiopathic intracranial hypertension patients

Idiopathic intracranial hypertension (IIH) is a neurological disorder of unknown etiology and ambiguous pathophysiology due to cerebrospinal fluid dysregulation. This study is designed to evaluate the role of ...

Authors: Ali Ahmed Abou Elmaaty, Carmen Ali Zarad, Tamer Ibrahim Belal and Tamer Sabry Elserafy

Impact of depression on quality of life in systemic lupus erythematosus patients

Depression is common in systemic lupus erythematosus (SLE) and is an unmeasured risk factor, yet its symptoms can be neglected in standard disease evaluations. The purpose of this study was to assess the frequ...

Authors: Eman M. Khedr, Rania M. Gamal, Sounia M. Rashad, Mary Yacoub and Gellan K. Ahmed

Study of cognitive impairment and genetic polymorphism of SLC41A1 (rs11240569 allele) in Parkinson’s disease in Upper Egypt: case-control study

Parkinson’s disease is one of the neurodegenerative disorders that is caused by genetic and environmental factors or interaction between them. Solute carrier family 41 member 1 within the PARK16 locus has been...

Authors: Hamdy N. El-Tallawy, Tahia H. Saleem, Wafaa M. Farghaly, Heba Mohamed Saad Eldien, Ashraf Khodaery, Sherif A. Sayed, Ahmed A. Helaly and Hassan Mohammed Elnady

Surgical management of tentorial meningiomas: case series

There are several surgical strategies involved in the treatment of patients with tentorial meningioma, and choosing the most appropriate one is not straight forward. Our study aims to illustrate our experience...

Authors: Hussein Mohammed Soffar, Mohamed Mohsen El Shimy, Hieder Al-Shami and Ahmed M. Salah

Idiopathic intracranial hypertension with multiple cranial nerve palsies in 10 years old thin Sudanese boy: case report

Idiopathic intracranial hypertension is a rare neurological disorder of unknown etiology. It is characterized by symptoms and signs of raise intra cranial pressure, normal brain neuroimaging, and high opening ...

Authors: Mumen Abdalazim Dafallah, Elsanosi Habour, Esraa Ahmed Ragab, Zahraa Mamoun Shouk and Mohammed Izzadden

Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study

Disturbances in structural and synaptic plasticity have been linked to depression and suicidal ideation. One of the major neurotrophic factors, the brain-derived neurotrophic factor (BDNF), is involved in the ...

Authors: Amira Mohamed Yousef, Ghada Mohamed Salah El-Deen, Abdallah Saad Ibrahim and Amany Elshabrawy Mohamed

Case reports of cerebral sinus venous thrombosis in COVID-19 patients

Coronavirus disease 2019 (COVID-19) pandemic has started in December 2019 and still ongoing. The disease has been expanding rapidly with a high variety of phenotypes from asymptomatic, mild respiratory tract i...

Authors: Prysta Aderlia Sitanggang, Kumara Tini, Ni Made Susilawathi, Ida Ayu Sri Wijayanti, Putu Utami Dewi and Dewa Putu Gde Purwa Samatra

A novel surgical rotation overlapping craniotomy technique for the management of non-syndromic anterior plagiocephaly

Nonsyndromic anterior plagiocephaly is one of the most common types of craniosynostosis. Different surgical techniques to correct this deformity have been developed with dissatisfaction among many surgeons. In...

Authors: Mohamed Reda Rady, Mamdouh Abo Elhassan and Omar Youssef

Extradural anterior clinoidectomy in surgical management of clinoidal meningiomas

Despite the recent advances in skull base surgery, microsurgical techniques, and neuroimaging, yet surgical resection of clinoidal meningiomas is still a major challenge. In this study, we present our institut...

Authors: K. El-Bahy, Ashraf M. Ibrahim, Ibrahim Abdelmohsen and Hatem A. Sabry

Non-protected carotid artery stenting for symptomatic carotid stenosis in low resource settings

The use of a distal cerebral protection device during extracranial carotid artery stenting is still a matter of debate. The aim of this work was to evaluate the safety of performing carotid artery stenting pro...

Authors: Ayman H. El-Sudany, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros and Ahmed El-Bassiouny

Awake surgery for lesions near eloquent brain under scalp block and clinical monitoring: experience of single center with limited resources

Surgery of the brain tumors near eloquent areas carries the risk of either disabling neurological deficit or inadequate resection with bad prognosis in both situations. Awake surgery is the gold standard proce...

Authors: Esam Abdelhameed, Mohamed Shebl Abdelghany, Hazem Abdelkhalek and Hytham Ibrahim Shokry Elatrozy

Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Neuropsychiatric systemic lupus erythematosus (NPSLE) is well known for its varying presentations and poor outcomes, but little is evident about its distribution and characteristics among the Bangladeshi popul...

Authors: Fahima Hossain, Mohammad Delwer Hossain Hawlader, Dipak Kumar Mitra, Mohammad Hayatun Nabi and Md. Mujibur Rahman

Rare case of recurrent stroke in a patient with eosinophilic granulomatosis with polyangiitis: a case report

Central nervous system involvement is rarely described in eosinophilic granulomatosis with polyangiitis (EGPA) and occurs in 5–9% of patients. Among central nervous system manifestations, cerebral infarctions ...

Authors: Mirjana Arsenijević, Nikola Ivančević, Dejana Jovanović, Milan Radović and Ivana Berisavac

Duplex ultrasonography as prognostic tool of acute ischemic stroke patients

Cerebral stroke is a major source of mortality and morbidity. Duplex ultrasonography is used to evaluate carotid and cerebral arteries. The objectives of this work are to study the correlation between carotid ...

Authors: Mohamed El-Sayed El-khatib and Shereen Ahmed El Ahwal

Electrophysiological biomarkers of central nervous system affection in cases of chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary disease is associated with significant systemic abnormalities which includes systemic inflammation and neurohormonal activation that are considered the main mechanisms of the path...

Authors: Hossam Abd El Monem Ali and Ahmed Salama Al-Adl

Intravenous thrombolysis outcome in posterior vs anterior circulation stroke in a tertiary stroke center in Egypt

Intravenous thrombolysis (IVT) with alteplase is the first-line therapy for acute ischemic anterior and posterior circulation strokes (ACS and PCS).

Authors: Nourhan Abdelmohsen Taha, Hala El Khawas, Mohamed Amir Tork and Tamer M. Roushdy

Ondine’s curse, a fatal infarction diagnosed by polysomnography and saved by ventilation: a case report

Lateral medullary syndrome causing Ondine’s curse is a rare yet fatal brainstem infarction. Any patient presenting with lateral medulla infarction ought to be well observed and a polysomnography must be ordere...

Authors: Hany Aref, Tamer Roushdy, Amr Zaki and Nevine El Nahas

How patients with schizophrenia “as a Victim” cope with violence in Indonesia: a qualitative study

There is increasing concern about the level of violence and people with schizophrenia. However, research about violence in correlation with schizophrenia mostly focuses on patients as offenders rather than vic...

Authors: Iyus Yosep, Henny Suzana Mediani, Linlin Lindayani and Aat Sriati

Omentin-1: a biomarker in large artery ischaemic stroke patients

Omentin-1 is a novel adipocytokine that is related to atherosclerosis-based ischaemic cardiovascular disease and stroke. Previous studies have linked its lower levels with poor stroke outcomes. We aimed to ass...

Authors: Elham Nasif, Osama A. Ragab, Mahmoud E. Elhassanien and Ayman M. Al-Malt

Risk homozygous haplotype regions for autism identifies population-specific ten genes for numerous pathways

Recessive homozygous haplotype (rHH) mapping is a reliable tool for identifying recessive genes by detecting homozygous segments of identical haplotype structures. These are shared at a higher frequency amongs...

Authors: Swati Agarwala and Nallur B. Ramachandra

Neurological manifestations and neuroimaging findings in patients with SARS-CoV2—a systematic review

The COVID-19 pandemic has drastically affected everyone in a hit or miss manner. Since it began, evidence of the neuro-invasive potential of the virus has been intensifying significantly. Several pathways have...

Authors: Nikita Mohan, Muhammad Ali Fayyaz, Christopher del Rio, Navpreet Kaur Rajinder Singh Khurana, Sampada Sandip Vaidya, Esteban Salazar, John Joyce and Amrat Ayaz Ali

Mechanical thrombectomy (MT) for acute ischemic stroke (AIS) in COVID-19 pandemic: a systematic review

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially, COVID-19 is a disease that attacks the respiratory tract, but now the clinica...

Authors: Aditya Kurnianto, Dodik Tugasworo, Yovita Andhitara, Retnaningsih, Rahmi Ardhini and Jethro Budiman

Telephone-based assessment of multiple sclerosis patients at Ain Shams University Hospital in the coronavirus disease 2019 pandemic

Assessment of multiple sclerosis (MS) patients during the era of the coronavirus disease 2019 (COVID-19) pandemic was confronted with the overwhelmed healthcare facilities in Egypt and fear of the patients to ...

Authors: Mohamed A. Abdel Hafeez, Dina A. Zamzam, Mahmoud S. Swelam, Alaa Abo Steit, Janet Masoud, Azza Abdel Nasser, Ahmed Hazzou, Eman Hamid, Hany Aref, Magd F. Zakaria and Mohamed M. Fouad

Determinants of quality of life changes with plasmapheresis in patients with myasthenia gravis

Immunomodulation, including IVIG and plasma exchange, is useful for a crisis or severe exacerbation. Plasma exchange may be slightly faster and more effective in a myasthenic crisis than IVIG. The aim of the c...

Authors: Ibraheim Al-Ahmer and Hosna Elshony

Epidemiological profile of psychiatric illnesses in the province of Taza, Morocco: case of a study on a schizophrenic sub-population in the Ibn Baja Hospital

The objective of this study is to assess the prevalence of major psychiatric disorders and to plot some characteristics of the schizophrenic sub-population in the study area.

Authors: El Hassan Ouanouche, Hasnae Lamine, Asmae Tliji, Hajar Hourmattallah, Ali Ouichou, Aboubaker El Hessni and Abdelhalim Mesfioui

A review on SARS-CoV-2 and stroke pathogenesis and outcome

Severe acute respiratory syndrome corona virus 2 hit strongly and hardly the entire globe for more than 1 year with a morbidity exceeding 139 million and a mortality approaching 3 million worldwide since its e...

Authors: Tamer Roushdy and Eman Hamid

Botulinum toxin type A for painful diabetic neuropathy: an open-label study

A large proportion of painful diabetic neuropathy cases either do not respond or are intolerant to the currently available oral and physical therapies. There is encouraging evidence from a small number of stud...

Authors: Shahinaz Helmy, Tamer Emara and Amr Abdel Menem

COVID-19 Infection Stigma Scale: psychometric properties

Stigma has been noticed towards patients with COVID-19 in several regions of the world. This social discrimination has contributed to delay in diagnosis and treatment. Also, it may increase the suffering of th...

Authors: Hayam Mohammed Elgohari, Medhat Mohamed Bassiony, Mohammad Gamal Sehlo, Usama Mahmoud Youssef, Heba Mohamed Ali, Islam Shahin, Dina Sameh Elrafey and Rehab Saeed Mahdy

Unexplained worsening of parkinsonian symptoms in a patient with advanced Parkinson’s disease as the sole initial presentation of COVID-19 infection: a case report

Parkinson’s disease (PD) is a neurodegenerative condition that has been reported following viral infections in rare occasions. Several neurological complications have emerged in association with coronavirus di...

Authors: Walaa A. Kamel, Ismail Ibrahim Ismail, Mohamed Ibrahim and Jasem Y. Al-Hashel

Reflex memory theory of acquired involuntary motor and sensory disorders

Explicit and implicit memories are conserved but flexible biological tools that nature uses to regulate the daily behaviors of human beings. An aberrant form of the implicit memory is presumed to exist and may...

Authors: Matthias Oyigeya

Evaluation of risk factors for cerebral palsy

Cerebral palsy (CP) has been identified as one of the most important and common causes of childhood disabilities worldwide and is often accompanied by multiple comorbidities. CP is defined as a group of disord...

Authors: Dina Salama Abd Elmagid and Hend Magdy

The relationship of HLA-G 14-bp insertion/deletion genetic polymorphism to the risk of multiple sclerosis and its clinical phenotypes

Human leukocyte antigen (HLA)-G molecule has been suggested to have a potential immunomodulatory role in multiple sclerosis (MS). Genetic variant sites of HLA-G molecule have been reported to be associated wit...

Authors: Wafaa M. Farghaly, Heba M. Saad Eldien, Mohammed A. Sayed, Hassan M. Elnady, Ashraf Khodeary, Abdelhady R. Abdel-Gawad, Hamdy N. El-Tallawy, Mohammed G. Abdellatif and Hazem K. Alhewaig

The interictal activities load and cognitive performance of children with typical absence epilepsy

The description of childhood absence epilepsy (CAE) a benign self-limited generalized epilepsy has become a matter of debate. The objectives of this work were to evaluate the existence of psychiatric and cogni...

Authors: Shereen Ahmed ELAhwal, Yasser Abo Elfotoh El-Heneedy, Wafik Said Bahnasy, Reham Abdel Rahman Amer and Khaled Hussein Rashed

Gait and balance impairments in patients with subcortical vascular cognitive impairment

Subcortical vascular cognitive impairment (SVCI) is a subtype of vascular cognitive impairment associated with extensive cerebral small vessel diseases (CSVDs) imaging biomarkers. The objectives of this work w...

Authors: Mahmoud Ebrahim Mostafa Elhassanien, Yasser Abo Elfotoh El-Heneedy, Kareem Mohammed Ramadan, Mona Ahmed Kotait, Amr Elkholy, Mohammed Youssef Elhamrawy and Wafik Said Bahnasy

Guillain-Barre syndrome in 220 patients with COVID-19

This review summarises and discusses recent findings concerning the pathophysiology, clinical presentation, diagnosis, treatment, and outcome of SARS-CoV-2-associated Guillain-Barre syndrome (SC2-GBS). By the ...

Authors: Josef Finsterer and Fulvio A. Scorza

Prevalence of burnout among neurologists in Saudi Arabia

Burnout is a psychological syndrome defined as emotional exhaustion (EE), depersonalization (DP), and reduced personal accomplishment (PA) secondary to work stress. Burnout is widespread among medical workers....

Authors: Zina Ali Al-Qahtani and Adel Alhazzani

Decompressive laminectomy with instrumented posterolateral fusion for degenerative lumbar disease in elderly, is it safe and beneficial?

With improvement of health care in last decades, the age of general population increased. As the elderly with degenerative lumbar disease needs to remain physically active for more years, lumbar decompression ...

Authors: Ahmed A. Arab, Mohammed H. Eltantawy and Ashraf El-Desouky

Outcomes and issues of 12 chordomas treated in a single center

Chordomas stem from notochordal vestiges and rank as low-grade bone malignancies although fraught with high risk of recurrence. This study assesses the clinical outcomes of twelve chordoma cases treated in our...

Authors: Maria Karampouga, Fotis Tsetsos, Pavlos Sakellariou and Ioannis Baltas

Reliability and validity of Arabic version of the brief international cognitive assessment for multiple sclerosis: Egyptian dialect

Given the diversity of multiple sclerosis (MS) symptoms including cognitive impairment in certain domains, the need to develop a rapid and at the same time thorough tool for cognitive assessment is mandatory a...

Authors: Marwa Farghaly, Dawn W. Langdon, Nevin M. Shalaby, Hatem S. Shehata, Noha T. Abokrysha, Amr Hassan, Mohamed I. Hegazy, Alaa Elmazny, Sandra Ahmed, Shaimaa Shaheen, Alshaimaa S. Othman, Osama Yacoub and Nirmeen A. Kishk

Assessment of the outcome of percutaneous pedicle screws in management of degenerative and traumatic dorsal and lumbar pathologies

Percutaneous pedicle screw technique is relatively a recent technique that evolved the concept of posterior spinal instrumentation, utilizing familiar fluoroscopic landmarks to guide the procedure of screws in...

Authors: Ayman Hussein, Hamdy Ibrahim, Hazem Mashaly, Sameh Hefny and Abdelrahman El Gayar

Guillain-Barre syndrome after coronary artery bypass graft surgery: a case report and literature review

Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy, often preceded by an infection. Rarely, it is preceded by a surgical procedure. Most of the postsurgical GBS cases are reported with the neuros...

Authors: Sajid Hameed, Lubna Ashraf Jafri and Dureshahwar Kanwar

Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population

Elderly people with epilepsy are large, but neglected group. Data on the predictive factors for recurrent seizures in the elderly population are inconclusive or are not known for the majority of patients. This...

Authors: Steven Emil Gerges, Mahmoud Hemeda El Rakawy, Naglaa Mohammed El Khayat, Yousry Abo Elnaga Abdelhamid, Ahmed Mohammed Hazzou, Hossam Mohammed Shokri and Mona Mokthar Wahid El din

Impact of gender, depression severity and type of depressive episode on efficacy and safety of escitalopram: an observational study on major depressive disorder patients in southern India

Antidepressant response is a complex trait influenced by clinical, demographic and genetic factors.

Authors: Tatiyana Mandal, Laxminarayana Kurady Bairy, Podila Satya Venkata Narasimha Sharma and Vijaya Lakshmi Valaparla

Depression facilitators from the perspective of Iranian patients with major depressive disorder: a qualitative research

Major depressive disorder is the most common psychological disorder and affects many people worldwide. Therefore, it is important to identify the factors that cause or facilitate this disorder.

Authors: Milad Rezaiye, Moloud Radfar and Masumeh Hemmati MaslakPak

Motor unit number estimation versus compound muscle action potential in the evaluation of motor unit loss in amyotrophic lateral sclerosis

Motor neuron loss is the primary pathologic feature of amyotrophic lateral sclerosis (ALS). An estimate of the number of surviving motor units (MUs) represents a direct measure of the disease state in ALS. The...

Authors: Arwa Khalid Ibrahem, Akram Mohammed Al-Mahdawi and Farqad Bader Hamdan

Recurrent spontaneous CSF rhinorrhea: combined endo-nasal endoscopic repair with lumbo-peritoneal shunt insertion

Spontaneous cerebrospinal fluid (CSF) leaks are associated with high morbidity and recurrence rates. Most cases had increased intracranial pressure (ICP) on presentation. There is still controversy regarding t...

Authors: Ahmed Y. Soliman, Kamal Ebeid and Amr Abu Elfadle

Multiple sclerosis patients and COVID-19

Coronavirus disease 2019 (COVID-19) is now a major issue for all fields of medicine. Due to the higher mortality rate among patients with chronic diseases, it has also caused concern in patients with multiple ...

Authors: Hubert Mado and Monika Adamczyk-Sowa