Articles

Evaluation of F wave and split hand index in patients with amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by gradual disturbance of both upper and lower motor neurons (LMN). In ALS, muscle wasting favors the abductor pollicis brevis (APB) and first dorsal intero...

Authors: Noor H. Mohammed, Farqad B. Hamdan and Akram M. Al-Mahdawi

Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke?

Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique th...

Authors: Mervat Mostafa, Maged Abdel Naseer, Ramy Edward, Mohammad Edrees and Dalia M. Labib

Endovascular stenting of medically refractory intracranial arterial stenotic (ICAS) disease (clinical and sonographic study)

Atherosclerotic intracranial arterial stenosis (ICAS) is one of the most common causes of stroke worldwide and is associated with a high risk of recurrent stroke. Patients with a recent transient ischemic atta...

Authors: Ayman Mohamed Nassef, Eman Mahmoud Awad, Ahmed Ali El-bassiouny, Hossam Eldin Mahmoud Afify, Romany Adly Yousef and Mohamed Ahmed Shafik

Biochemical and structural magnetic resonance imaging in chronic stroke and the relationship with upper extremity motor function

Recovery of upper extremity (UE) motor function after stroke is variable from one to another due to heterogeneity of stroke pathology. Structural and biochemical magnetic resonance imaging of the primary motor...

Authors: Mohamed Mahmoud Mostafa, Eman Mahmoud Awad, Ahmed Mohamed Hazzou, Mohamed Khaled Ahmed Elewa, Tougan Taha Abdel Aziz and Dalia Maher Samy

The effect of nocturnal epileptic seizures on cognitive functions in children with idiopathic epilepsy

Cognitive impairment is a common finding epileptic children. Studies have linked nocturnal epileptic discharges to delayed cognitive abilities in children.

Authors: Ayman M. Al-Malt, Shereen A. Abo Hammar, Khaled H. Rashed and Osama A. Ragab

Effect of extracorporeal shock wave therapy on different severities of carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome worldwide.

Authors: Usama Mohammad Rashad, Nirmeen A. Kishk, Waleed Talat Mansour, Amani M. Nawito, Alshaimaa Sobhi Khalil, Hanan Helmy and Tarek Kamal Zayed

Bladder and urodynamic changes in multiple sclerosis

Urinary dysfunction is a common symptom during the course of multiple sclerosis (MS). Long-term follow-up of the natural history of bladder dysfunction in MS has been seldom addressed.

Authors: Hesham Torad, Nevin Shalaby, Hussein Aly Hussein, Samih Z. Sadek, Mohamed S. Abdelazim, Ahmed Yehia, Samer Morsy and Shaimaa H. Soliman

Isolated subtle asymmetric slowing on EEG leading to a diagnosis of autoimmune encephalitis

Autoimmune encephalitis presents with subacute neurological, psychiatric, and behavioral symptoms. In many cases, MRI and CSF studies return normal. Laboratory testing for pathogenic neuronal antibodies is lim...

Authors: Belal Aldabbour, Khalid El-Salem, Suha Aqaileh, Deema Obiedat, Mohammad Qasaimeh, Majdi Al Qawasmeh, Abdel-Hameed Al-Mistarehi and Ahmed Yassin

Vitamin D status in idiopathic Parkinson’s disease: an Egyptian study

Vitamin D is suggested to play an important role in neurodegenerative disorders.

Authors: Ebtesam Mohamed Fahmy, Mohamed Elsayed Elawady, Sahar Sharaf, Sarah Heneidy and Rania Shehata Ismail

COVID-19 pandemic and the risk of infection in multiple sclerosis patients on disease modifying therapies: “what the bleep do we know?”

The novel coronavirus which emerged in Wuhan province of China has taken world by surprise. Since been diagnosed in December 2019, it has been termed a “Pandemic” and there is a growing concern in physicians a...

Authors: Salman Mansoor, Siobhan Kelly, Kevin Murphy, Aine Waters and Nauman Saleem Siddiqui

Elucidation of the levels of vitamin D, calcium, and magnesium in the serum of Egyptian migraine patients: a case-control study

Migraine, although, is a prevalent disease; its pathogenesis is complex and still not fully elucidated. The effect of vitamin D on various neurological disorders is thought to be exerted either directly via it...

Authors: Dorreya A. Elsayed, Karam S. Amin, Ibrahim A. Elsayed and Noha A. Hashim

A study of diffusion tensor imaging of median nerve in diabetic peripheral neuropathy

To evaluate the role of diffusion tensor imaging (DTI) in the evaluation of diabetic peripheral neuropathy (DPN) compared to clinical scores and nerve conduction studies (NCS).

Authors: Ramy Edward, Ahmed M. Abdelalim, Amal S. Ashour, Lamia Afifi and Aussan Al-Athwari

Magnitude, risk factors and outcomes of stroke at Debre Markos Referral Hospital, Northwest Ethiopia: a retrospective observational study

Stroke is one of the leading causes of death and disability in developing countries. The burden of stroke has varied widely in different areas, and there is a paucity of information about stroke in the selecte...

Authors: Henok Mulugeta, Amare Yehuala, Dessalegn Haile, Nakachew Mekonnen, Getenet Dessie, Getachew Mullu Kassa, Zerihun Shimelis Kassa and Tesfa Dejenie Habtewold

Bell’s palsy: clinical and neurophysiologic predictors of recovery

The annual incidence of Bell’s palsy (BP) is 15 to 20 per 100,000 with 40,000 new cases each year, and the lifetime risk is 1 in 60. For decades, clinicians have searched the prognostic tests of sufficient acc...

Authors: Mohamed E. Flifel, Tamer Belal and Ali A. Abou Elmaaty

Role of diffusion-weighted imaging in differentiation between posterior fossa brain tumors

Diffusion-weighted imaging (DWI) is an imaging modality using multi-section single-shot spin echo planar imaging (EPI) sequence which is extremely sensitive for detection of water motion within intra, extra, a...

Authors: W. F. Mustafa, M. Abbas and L. Elsorougy

Functional outcome of joint mobilization added to task-oriented training on hand function in chronic stroke patients

Approximately half of stroke patients show impaired upper limb and hand function. Task-oriented training focuses on functional tasks, while joint mobilization technique aims to restore the accessory movements ...

Authors: Asmaa Sabbah, Sherine El Mously, Hanan Helmy Mohamed Elgendy, Mona Adel Abd Eltawab Farag and Abeer Abo Bakr Elwishy

Comment to “The effects of Kinesio taping of lower limbs on functional mobility, spasticity, and range of motion of children with spastic cerebral palsy” by Mirjavad Tabatabaee et al.

Authors: Faizan Zaffar Kashoo and Mehrunnisha Ahmad

Effects of mobile phones electromagnetic radiation on patients with epilepsy: an EEG study

Recently, an exceptional increase was witnessed in cell phone users. The brain has greater exposure to the electromagnetic field (EMF) created during mobile phone use than the rest of the body, which may impai...

Authors: Radwa Azmy, Reham Shamloul, Noha Abdalla Farag Elsawy, Saly Elkholy and Eman Maher

Epilepsy surgery for refractory seizures: a systematic review and meta-analysis in different complications

Nearly one-third of epilepsy patients are refractory/resistant to medical treatment. Developments made in surgical techniques have significantly increased the effectiveness and safety of these techniques, as s...

Authors: Maryam Joudi Mashhad, Hadi Harati, Fateme Parooie and Morteza Salarzaei

Relation between serum amylin level and epilepsy

Epilepsy is a neurological disorder characterized by convulsions. Identification of biological pathways underlying epilepsy and novel genes may shed light on the pathogenesis of epilepsy as well as new targets...

Authors: Necla Benlier, Gokhan Ozer and Nuri Orhan

Role of nerve ultrasound versus electrophysiological studies in the evaluation of nerve injuries

High-resolution ultrasonography (US) is a non-invasive, readily applicable imaging modality capable of depicting real-time static and dynamic information concerning the peripheral nerves and their surrounding ...

Authors: Neveen Mohamed Elfayoumy, Hanan Helmy Elgendy, Marwa Saad Afify Saad and Amira A. Labib

Multiple level anterior cervical discectomy and fusion versus posterior laminectomy for the management of multilevel cervical spondylotic myelopathy: clinical and radiological outcome

Though both anterior and posterior approach are used for the management of multilevel cervical spondylotic myelopathy (CSM), the choice between both approaches remains to be of considerable debate.

Authors: Omar El Farouk Ahmed and Ahmed Galal

Isolated Horner’s Syndrome Secondary To Rhinosinusitis: A Case Report And Literature Review

Horner’s syndrome (HS) is characterized by unilateral ptosis, ipsilateral miosis with normally reactive pupil, and in some cases, ipsilateral facial anhidrosis.

Authors: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara, Juliana Oliveira Freitas Silveira and Paulo Gilberto Medeiros Jauris

Management of recurrent unilateral lumbar disc herniation in a single level: unilateral versus bilateral pedicle screws fixation with interbody fusion

Lumbar interbody fusion procedure is a recognized surgical technique in management of a variety of lumbar pathologies including recurrent lumbar disc prolapse. Interbody fusion augmented by pedicle screw fixat...

Authors: Omar El Farouk Ahmed, Sherif H. Morad and Ahmed S. Abdelbar

Role of serum biomarkers and transcranial Doppler in predicting cerebral vasospasm after aneurysmal subarachnoid hemorrhage

Aneurysmal subarachnoid hemorrhage (aSAH) can have serious consequences related to vasospasm and delayed cerebral ischemia (DCI). Serum biomarkers have emerged as a promising assessment tool to facilitate earl...

Authors: Maged Mohammad Abdelnaseer, Ahmed Abdelkader Nemr, Sandra Mohammad Ahmed, Alshaimaa M. Aboul fotouh, Amro Mohammad Ahmed Soliman, Ahmed Abdullah El-Fiki and Safinaz Hassan Osman

Single level anterior cervical discectomy and fusion versus dynamic cervical implant: clinical and radiological outcome

Although anterior cervical discectomy and fusion (ACDF) is considered a gold standard approach for surgical management of cervical disc herniation syndromes, the use of dynamic cervical implant (DCI) provided ...

Authors: Omar El Farouk Ahmed and Ahmed Galal

Can electrophysiological tests be used as screening tools in detection of cognitive impairment in obstructive sleep apnea hypopnea syndrome?

One of the most prevalent sleep disorders is obstructive sleep apnea (OSA). Patients with OSA have increased risk of car and work place accidents which may be attributed to cognitive impairment due to poor sle...

Authors: Mona M. Nada, Eman A. Maher, Mye A. Basheer and Leqaa A. El-Mekkawy

Anti-GAD-associated limbic encephalitis: an unusual clinical manifestation from northwest of Ireland

We report an unusual manifestation of anti-GAD-associated limbic encephalitis in a 59-year-old man following pacemaker insertion for cardiac pauses. Clinically, the association of anti-GAD antibody with limbic...

Authors: Salman Mansoor and Kevin Murphy

Salivary alpha-synuclein (total and oligomeric form): potential biomarkers in Parkinson’s disease

Parkinson’s disease (PD) is one of the most common degenerative diseases of the central nervous system (CNS). Alpha-synuclein (A-syn) plays a critical role in the pathogenesis of PD. The close relation between...

Authors: Hala Shaheen, Sayed Sobhy, Sherine El Mously, Marwa Abuomira and Mohamed Mansour

Detection of airway protective level of the cough reflex in acute stroke patients

The most common respiratory complications in cerebrovascular strokes were respiratory infection, pulmonary edema, acute lung injury (ALI) acute respiratory distress syndrome (ARDS) and pulmonary embolism (PE)....

Authors: Ehab Shaker Belal, Samah Selim, Alshaimaa M. Aboul fotouh and Asmaa Mohammad

Polyunsaturated fatty acids supplementation can improve specific language impairment in preschool children: a pilot study

Speech and language are one of the higher cognitive brain functions. Language delay is one of the major concerns of child health in Egypt. Speech therapy is the standard management in language delay.

Authors: Dalia G. Yasseen, Nermien E. Waly and Khaled O. Abdulghani

The role of left prefrontal transcranial magnetic stimulation in episodic migraine prophylaxis

The aim of the study was to examine the prophylactic role of repetitive transcranial magnetic stimulation (rTMS) on the frequency, and severity of migraine attacks in episodic migraineurs who failed medical tr...

Authors: Randa Amin, Tamer Emara, Samia Ashour, Mahmoud Hemeda, Nahed Salah Eldin, Salma Hamed, Sara Shouman and Mohamed Shouman

Impact of insulin resistance and metabolic syndrome on disability in patients with multiple sclerosis

Currently, little is known regarding the association of metabolic comorbidities and disability among multiple sclerosis (MS) patients.

Authors: Rasha Hassan Soliman, Hanan Mohamed Farhan, Mohamed Hegazy, Mohammed Ibrahim Oraby, Shaimaa Hossam Kamel and Amr Hassan

Neutrophil–lymphocyte ratio and response to plasmapheresis in Guillain–Barré syndrome: a prospective observational study

Guillain–Barré Syndrome (GBS) is one of the most severe neurological diseases that causes marked disability and even death.

Authors: Noha Ali Hashim, Wafaa Samir Mohamed and Engy Mohammed Emad

Cognitive performance in patients with chronic tension-type headache and its relation to neuroendocrine hormones

Tension-type headache is the most common headache to be seen in clinical practice. Depression is highly prevalent in chronic tension-type headache (CTTH) patients attending the clinical settings. Cognitive imp...

Authors: Mamdouh Ali Kotb, Ahmed M. Kamal, Daifallah Al-Malki, Aliaa S. Abd El Fatah and Yassmin M. Ahmed

Systemic lupus erythematosus presenting with status epilepticus and acute cardiomyopathy with acute heart failure: case report

Systemic lupus erythematosus is a connective tissue disorder, which causes complex multi organ involvement. Neurological and cardiac manifestations have been well noted but complications such as status epilept...

Authors: H. M. M. T. B. Herath and Aruna Kulatunga

Heart versus brain: a case of ictal asystole in temporal lobe epilepsy

Ictal asystole is a rare phenomenon. Most reported cases are in persons with long-standing focal epilepsy originating from the temporal lobe. Its occurrence may complicate the clinical presentation or delay di...

Authors: Ahmed Yassin, Belal Aldabbour, Anto Bagić and Alexandra Urban

Post-stroke sleep disorders in Egyptian patients by using simply administered questionnaires: a study from Ain Shams University

Stroke is a leading cause of disability worldwide with grave morbidity and mortality. Sleep and stroke have a definite intermingling neuropathological relationship, so along with expeditious acute management, ...

Authors: Alia H. Mansour, Maged Ayad, Naglaa El-Khayat, Ahmed El Sadek and Taha K. Alloush

Role of interleukin-6 in ischemic stroke outcome

High levels of inflammatory markers such as C-reactive protein (CRP) and interleukin (IL)-6 are associated with worse outcome after ischemic stroke.

Authors: Hani Mohamed Amin Aref, Nagia Ali Fahmy, Salma Hamed Khalil, Mai Fathy Ahmed, Ahmed ElSadek and Mohamed Osama Abdulghani

Characteristics of A-waves in patients with amyotrophic lateral sclerosis (ALS) versus demyelinating neuropathies (DN)

Detect the occurrence and characteristics of A-waves in amyotrophic lateral sclerosis (ALS) and demyelinating neuropathies (DN).

Authors: Hebatallah R Rashed

Value of magnetic resonance spectroscopy in geriatric patients with cognitive impairment

Mild cognitive impairment is a transitional stage prior to dementia, and it is reported in depressed patients. Early diagnosis could predict the reversible etiologies and prevent further deterioration. Proton ...

Authors: Mamdouh Ali Kotb, Ahmed M. Kamal, Nasser M. Aldossary, Ayman A. Alsify and Yassmin M. Ahmed

Gender difference in health issues and cognitive functions among an Egyptian normal elderly population

Aging is associated with changes in cognitive functions. However, many other factors may affect cognitive functions and this interaction needs further assessment.

Authors: Enas Alsayyad, Azza Abbas Helmy, Nirmeen A. Kishk, Marwa Farghaly, Amany H. Ragab and Shaimaa Ibrahim El-Jaafary

The myth and truth of a comprehensive stroke scale

The National Institutes of Health Stroke Scale (NIHSS) has been found to be biased toward the left hemispheric and motoric functions providing minimal assessment to the right hemispheric language and cognitive...

Authors: Hani M. Zakieldine, Mohamed A. Turk, Rana F. Hashem and Mohamed A. Shafik

Do cerebral microbleeds affect cognition in patients with symptomatic small vessel disease?

Dementia and cognitive impairment are becoming increasingly a major health problem, pronounced by increased life expectancy. Cerebral small vessel disease (cSVD) is among the major causes of cognitive deterior...

Authors: Kholoud Mahmoud Abdullah, Hany Mahmoud Zakieldin, Iman Mohamed Bayomy, Maryse Youssef Awadallah and Mona Mokhtar Wahid El Din

Natalizumab-induced hyporegenerative anaemia and leukopenia: a case report

Authors: Salman Mansoor, Siobhan Kelly, Aine Burke, Mohammad Hijaz Adenan, Eimear Joyce, Aine Waters, Grainne McPartland and Kevin Murphy

Sleep pattern in epilepsy patients: a polysomnographic study

Sleep disorders and epilepsy commonly exist and affect each other. Patients with epilepsy often complain of poor sleep and on the other hand, poor sleep makes epilepsy control difficult.

Authors: Mohamed A. Tork, Hebatallah R. Rashed, Lobna Elnabil, Nahed Salah-Eldin, Naglaa Elkhayat, Ayman A. Abdelhady, M. Ossama Abdulghani and Khaled O. Abdulghani

One-year evaluation of epiduroscopy in chronic back pain with and without radiculopathy: a retrospective study

Back pain is a frequent complaint among the individuals in the society. It significantly affects the daily activities and the social and psychological life aspects leading to an economic health burden. Epiduro...

Authors: Mert Akbas, Huseyin Babun, Haitham Hamdy Salem, Tamer Hussien Emara, Shereen Elmosly, Emel Gunduz, Bilge Karsli and Fatih Asik

Serum apolipoprotein A1: a predictor and prognostic biomarker in acute ischemic stroke

The apolipoprotein A1 level is recognized as a better indicator of cardiovascular disease than other cholesterol measures.

Authors: Mai A. Eldeeb, Amr S. Zaki, Samia Ashour, Azza Abdel Nasser, Ahmed El Bassiouny and Khaled O. Abdulghani

A hospital-based study of post-stroke aphasia: frequency, risk factors, and topographic representation

The crude prevalence rate of stroke in Qena, Egypt, is high (922/100,000). For the first time, we estimate the frequency of aphasia following the first-ever ischemic stroke and its relationship to the site of ...

Authors: Eman M. Khedr, Mohamed A. Abbass, Radwa K. Soliman, Ahmed F. Zaki, Aymen Gamea, Noha Abo El-Fetoh and Mahmoud A. Abdel-Aaal

Blood biomarkers for stroke: the role of thioredoxin in diagnosis and prognosis of acute ischemic stroke

Oxidative stress plays a crucial role in the pathophysiology of acute ischemic stroke. Thioredoxin exists and released from cells during inflammation and oxidative stress and was recognized as an oxidative-str...

Authors: Mohammed I. Oraby and Radwa A. Rabie