Table 4 Comparison of different VDR c.1056A > G and c.1025-49C > A gene variants regarding main clinical parameters in MS patients
Gene | n | Age | Age at onset | Duration of illness (years) | EDSS score | Total no. of attacks | |
|---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Median (IQR) | Median (IQR) | Median (IQR) | |||
VDR c.1056A > G | A/A | 12 | 30.3 ± 10 | 26.3 ± 9.6 | 2 (1.75–4.25) | 2.75 (1–5.625) | 3 (2–4.25) |
A/G | 23 | 30.7 ± 8.5 | 24.6 ± 8.1 | 5 (2–9) | 1.5 (1–3.75) | 3.5 (2–5) | |
G/G | 15 | 32.3 ± 9.3 | 25.7 ± 6.6 | 6 (3–8.5) | 2.5 (1–4.75) | 3 (2.5–4.5) | |
P-value | 0.738* | 0.601* | 0.240** | 0.712** | 0.855** | ||
VDR c.1025-49C > A | A/A | 26 | 29.7 ± 7.6 | 23.6 ± 5.6 | 6 (1.25–8.75) | 2.5 (1.125–5.875) | 3 (2–5) |
A//C | 18 | 32.3 ± 9.2 | 26.7 ± 8.8 | 4 (2–6.75) | 1.25 (1–3.5) | 3 (2–4.75) | |
C/C | 6 | 33.3 ± 13.5 | 28.8 ± 12.7 | 4 (2.5–6.25) | 1.5 (1–3.5) | 3.5 (3–4.75) | |
P-value | 0.599* | 0.471* | 0.887** | 0.339** | 0.856** | ||