Fig. 2

Contrast-enhanced brain magnetic resonance imaging show miliary brain metastases (also called “carcinomatous encephalitis”) from malignant melanoma. A Fluid-attenuated inversion recovery image shows the presence of some hyperintense signal areas, most evident at the level of the basal ganglia. B Fast low-angle shot image shows no brain hemosiderin deposits. C, D Unenhanced Turbo Spin Echo T1-weighted images in supra-tentorial and sub-tentorial regions show the presence of multiple intra-axial hyperintense signal lesions involving also the perivascular spaces, as for melanotic pattern. E, F Enhanced Turbo Spin Echo T1-weighted images in supra-tentorial and sub-tentorial regions show post-contrast impregnation of the multiple intra-axial lesions described in C and D. G Enhanced three-dimension magnetization-prepared rapid gradient-echo T1-weighted image confirms the presence of multiple intra-axial supra- and sub-tentorial lesions with post-contrasts impregnation; the cervical spinal cord included in the study shows no signal alterations