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Table 2 Regression analysis of predictors of intractability

From: Genetic generalized epilepsy: factors associated with drug resistance polytherapy

Intractable

P value

OR

95% CI

Lower

Upper

Age at onset

0.451

0.975

0.914

1.041

Nocturnal seizures

0.805

1.106

0.495

2.472

Number of seizure types

0.361

1.301

0.739

2.291

Seizure frequency (GTC) before treatment (number in year)

 < 0.001

1.113

1.057

1.171

Absence seizures

0.005

0.409

0.209

0.796

H\O CAE

0.339

0.346

0.039

3.051

Catamenial seizures (female)

 < 0.001

8.085

2.786

23.464

Clusters

0.143

1.915

0.803

4.566

Valproate dose till first remission

 < 0.001

1.0029

1.0020

1.0039

EEG focal features

0.197

0.376

0.085

1.664

  1. GTCs generalized tonic clinic seizures, CAE childhood absence epilepsy, EEG electroencephalography, OR odds ratio, CI confidence interval