Table 6 Factors affecting the Δ change of NIHSS and mRS after 6 months and mortality (using regression analysis)
From: Predictors of the functional outcome after thrombolysis in an Egyptian patients’ sample
Δ Change of NIHSS after 6 months | mRS after 6 months | Mortality | ||||
|---|---|---|---|---|---|---|
Univariate | Univariate | Univariate | ||||
P | B (95% CI) | P | OR (95% CI) | P | OR (95% CI) | |
Dose (0.9) | 0.617 | − 0.565(− 2.8 to − 1.70) | 0.541 | 0.685 (0.204 to 2.302) | 0.111 | 0.168 (0.019 to 1.50) |
Age (years) | 0.629 | − 0.025 (− 0.130 to 0.08) | 0.054 | 1.070(0.999 to 1.145) | 0.173 | 1.059 (0.975 to 1.15) |
No of risk factors | 0.855 | 0.081 (− 0.816 to 0.98) | 0.306 | 1.277 (0.800 to 2.038) | 0.195 | 1.50 (0.811 to 2.78) |
Initial FAST − ED | 0.906 | 0.346 (− 0.429 to 1.12) | 0.011* | 1.943*(1.163 to 3.245) | 0.181 | 1.43 (0.845 to 2.43) |
Initial RACE | 0.958 | − 0.017 (− 0.653 to 0.6) | 0.001* | 2.638*(1.507 to 4.617) | 0.066 | 1.57 (0.971 to 2.54) |
Initial NIHSS | − | − | 0.005* | 1.354*(1.098 to 1.668) | 0.184 | 1.153 (0.935 to 1.42) |
Onset-to-presentation time | 0.340 | − 0.013 (− 0.042 to 0.02) | 0.181 | 1.010 (0.995 to 1.025) | 0.958 | 1.0 (0.983 to 1.019) |
Onset to tPA | 0.313 | − 0.017 (− 0.050 to 0.02) | 0.154 | 1.013 (0.995 to 1.032) | 0.997 | 1.00 (0.979 to 1.021) |
ASPECT score | 0.233 | − 1.012 (− 2.72 to 0.685) | 0.551 | 0.764 (0.316 to 1.848) | 0.442 | 0.670 (0.241 to 1.862) |
Hospital stay | 0.001* | − 0.139*(− 0.21 to − 0.06) | 0.012* | 1.174*(1.036 to 1.331) | 0.179 | 1.035 (0.985 to 1.087) |
SBP on admission | 0.424 | 0.016 (− 0.024 to 0.06) | 0.062 | 0.975 (0.950 to 1.001) | 0.193 | 0.976 (0.941 to 1.012) |
DBP on admission | 0.575 | 0.021(− 0.053 to 0.09) | 0.063 | 0.952 (0.904 to 1.003) | 0.183 | 0.954 (0.891 to 1.02) |
RBS on admission | 0.260 | − 0.007(− 0.019 to 0.01) | 0.201 | 1.004 (0.998 to 1.010) | 0.113 | 1.005 (0.999 to 1.012) |
Sex (females) | 0.109 | 1.80 (− 0.422 to 4.034) | 0.503 | 0.667(0.203 to 2.184) | 0.266 | 0.409 (0.085 to 1.97) |
Initial CT brain (MCA sign) | 0.491 | 0.469(− 0.89 to 1.836) | 0.872 | 1.263 (0.074 to 21.54) | 0.788 | 0.872 (0.320 to 2.37) |
Stroke type (cardioembolic LVO) | 0.614 | − 0.369 (− 1.84 to 1.10) | 0.013* | 18.33*(1.868 to 179.8) | 0.099 | 0.222 (0.037 to 1.3) |
Anterior vs. posterior circulation | 0.100 | 5.611 (− 1.12 to 12.3) | 0.872 | 1.263(0.074 to 21.54) | 0.266 | 5.14 (0.286 to 92.3) |
Hemorrhagic transformation | 0.264 | − 2.0(− 5.59 to 1.58) | 0.069 | 8.0 (0.850 to 75.28) | 0.299 | 2.750 (0.408 to 18.5) |
Midline shift | 0.012* | − 2.96*(− 5.24 to − 0.69) | 0.013* | 16.0*(1.788 to 143.1) | 0.151 | 2.486 (0.717 to 8.62) |
#Multivariate | #Multivariate | #Multivariate | ||||
P | B (95% CI) | P | OR (95% CI) | P | OR (95% CI) | |
Hospital stay | 0.048* | − 0.131*(− 0.261 to − 0.001) | ||||
Initial RACE | 0.048* | 3.954*(1.010 to 15.481) | ||||