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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 4 Serum vitamin B12, homocysteine, and methylmalonic acid levels between the studied groups

From: Evaluation of peripheral and autonomic nervous systems dysfunctions in patients with Parkinson’s disease

 

Control group

Drug-naïve patients with PD

PD on dopaminergic drugs

F-value

p-value

Tukey test

Vitamin B12 (pcg/ L) Mean ± SD

799 ± 48.86

745 ± 55.03

257.5 ± 76.26

133.5

0.001

P1:0.015

P2:0.001

P3:0.001

Homocysteine (µmol/L) Mean ± SD

13 ± 1.33

20.5 ± 1.17

35.58 ± 11.34

20.36

0.001

P1:0.001

P2:0.001

P3:0.001

Methylmalonic acid (µmol/L) Mean ± SD

0.39 ± 0.01

0.98 ± 0.02

1.14 ± 0.26

42.81

0.001

P1:0.001

P2:0.001

P3:0.001

  1. P1 (control versus drug-naïve patients with PD). P2 (control versus patients on dopaminergic drugs). P3 (drug-naïve patients with PD versus patients on dopaminergic drugs)
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