The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 3 Correlation of different sub-items of BICAMS to study variables

From: White matter lesion load and location in relation to cognitive impairment in relapsing–remitting multiple sclerosis

		SDMT	CVLT	BVM-RT
Age (years)	r	− 0.475**	− 0.318**	− 0.365**
Age (years)	Sig. (2-tailed)	< 0.001	0.002	< 0.001
Sex	r	− 0.016	0.137	− 0.024
Sex	Sig. (2-tailed)	0.882	0.197	0.822
Education years	r	0.496**	0.294**	0.442**
Education years	Sig. (2-tailed)	< 0.001	.005	< 0.001
Disease duration (months)	r	− 0.533**	− 0.506**	− 0.540**
Disease duration (months)	Sig. (2-tailed)	< 0.001	< 0.001	< 0.001
Number of relapses	r	− 0.493**	− 0.458**	− 0.517**
Number of relapses	Sig. (2-tailed)	< 0.001	< 0.001	< 0.001
Age at onset (years)	r	− 0.158	− 0.080-	− 0.080
Age at onset (years)	Sig. (2-tailed)	0.136	0.452	0.456
EDSS	r	− 0.525**	− 0.334**	− 0.457**
EDSS	Sig. (2-tailed)	< 0.001	0.001	< 0.001
DMT duration	r	− 0.345**	− 0.282**	− 0.322**
DMT duration	Sig. (2-tailed)	0.001	0.007	0.002
Time to start DMT	r	− 0.434**	− 0.433**	− 0.452**
Time to start DMT	Sig. (2-tailed)	< 0.001	< 0.001	< 0.001
Total WM-LL	r	− 0.428**	− 0.231*	− 0.399**
Total WM-LL	Sig. (2-tailed)	< 0.001	0.029	< 0.001
Juxtacortical WM-LL	r	− 0.136	− 0.044-	− 0.189
Juxtacortical WM-LL	Sig. (2-tailed)	0.202	0.683	0.075
Periventricular WM-LL	r	− 0.323**	− 0.204-	− 0.248*
Periventricular WM-LL	Sig. (2-tailed)	0.002	0.054	0.018
Infra tentorial WM-LL	r	− 0.096-	0.019	− 0.094
Infra tentorial WM-LL	Sig. (2-tailed)	0.371	0.862	0.378

* Statistically significant difference (p < 0.05)
**Statistically significant difference (p < 0.01)
DMT disease-modifying therapy, EDSS Expanded Disability Status Scale, WM-LL white matter lesion load

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