Table 2 Comparison between patients with and without cognitive impairment
RRMS group without cognitive impairment, n = 61 (mean ± SD) | RRMS group with cognitive impairment, n = 29 (mean ± SD) | P | |
|---|---|---|---|
Age (years) | 30.84 ± 7.94 | 36.76 ± 8.1 | < 0.001 |
Education years | 13.38 ± 3.61 | 8.48 ± 5.43 | < 0.001 |
Disease duration (months) | 38.33 ± 30.97 | 91.45 ± 62.89 | < 0.001 |
Number of relapses under the current DMT | 2.80 ± 1.82 | 4.69 ± 2.83 | 0.002 |
Age at onset (years) | 26.87 ± 8.02 | 27.72 ± 7.44 | 0.621 |
Current EDSS | 2.75 ± 1.69 | 4.172 ± 1.48 | < 0.001 |
Current DMT duration (months) | 16.54 ± 18.66 | 26.76 ± 25.05 | 0.057 |
Time to start DMT (months) | 21.77 ± 23.82 | 64.69 ± 62.01 | < 0.001 |
Total WM-LL | 14.89 ± 15.213 | 24.95 ± 15.31 | 0.005 |
Juxtacortical WM-LL | 5.23 ± 9.87 | 6.63 ± 12.44 | 0.599 |
Periventricular WM-LL | 9.41 ± 13.34 | 16.39 ± 13.81 | 0.028 |
Infratentorial WM-LL | 0.22 ± 0.44 | 0.28 ± 0.46 | 0.603 |