Table 1 Clinical and laboratory findings in the studied patients in relation to discharge outcome (n = 93)
From: Clinical and prognostic significance of baseline microRNA 223 in acute ischemic stroke
All patients n = 93 | Favorable outcome n = 44 | Unfavorable outcome n = 49 | p value | |
|---|---|---|---|---|
Age (years) mean ± SD | 64.5 ± 12.4 | 61.7 ± 11.0 | 70.5 ± 13.3 | < 0.001 |
Male/female n | 60/33 | 23/21 | 37/12 | 0.019 |
BMI (Kg/m2) mean ± SD | 32.1 ± 6.9 | 31.6 ± 6.1 | 32.6 ± 7.6 | 0.48 |
Risk factors n (%) | ||||
TIA | 43 (46.2) | 24 (54.6) | 19 (38.8) | 0.13 |
AF | 8 (8.6) | 1 (2.3) | 7 (14.3) | 0.039 |
Diabetes mellitus | 43 (46.2) | 18 (40.9) | 25 (51.0) | 0.33 |
Hypertension | 58 (62.4) | 27 (61.4) | 31 (63.3) | 0.85 |
Smoking | 13 (14.0) | 9 (20.5) | 4 (8.2) | 0.09 |
Affected side n (%) | ||||
Right | 46 (49.5) | 20 (45.4) | 26 (53.1) | 0.46 |
Left | 47 (50.5) | 24 (54.6) | 23 (46.9) | |
Site n (%) | ||||
Anterior circulation | 74 (79.6) | 32 (72.7) | 42 (85.7) | 0.11 |
Posterior circulation | 16 (17.2) | 9 (20.5) | 7 (14.3) | |
Both | 3 (3.2) | 3 (6.8) | – | |
TOAST classification n (%) | ||||
Large artery | 47 (50.5) | 24 (54.6) | 23 (46.9) | 0.76 |
Cardioembolic | 18 (19.4) | 8 (18.2) | 10 (20.4) | |
Small artery | 28 (30.1) | 12 (27.3) | 16 (32.7) | |
Infarct size n (%) | ||||
Small | 32 (34.4) | 22 (50.0) | 10 (20.4) | 0.002 |
Medium | 40 (43.0) | 18 (40.9) | 22 (44.9) | |
Large | 21 (22.6) | 4 (9.1) | 17 (34.7) | |
NIHSS | 14.3 ± 6.0 | 9.3 ± 3.5 | 18.9 ± 3.8 | < 0.001 |
Laboratory findings mean ± SD/median (IQR) | ||||
Hb (gm/dL) | 13.5 ± 1.0 | 13.3 ± 1.0 | 13.6 ± 0.9 | 0.14 |
WBCs (× 103/mL) | 6.5 ± 1.0 | 6.8 ± 1.1 | 6.4 ± 0.9 | 0.08 |
Platelets (× 103/mL) | 277.6 ± 71.2 | 270.6 ± 80.8 | 283.9 ± 61.4 | 0.37 |
FBG (mg/dL) | 117.6 ± 41.7 | 109.4 ± 31.3 | 124.9 ± 48.3 | 0.07 |
Cholesterol (mg/dL) | 159.2 ± 32.8 | 163.1 ± 38.2 | 155.8 ± 27.0 | 0.29 |
Triglycerides (mg/dL) | 138.5 ± 56.1 | 155.5 ± 59.8 | 163.2 ± 48.2 | 0.5 |
LDL (mg/dL) | 85.4 ± 25.8 | 85.3 ± 29.2 | 85.6 ± 22.7 | 0.96 |
HDL (mg/dL) | 46.1 ± 10.7 | 46.7 ± 11.4 | 45.6 ± 10.2 | 0.63 |
HbA1c (%) | 5.9 ± 1.2 | 5.6 ± 1.0 | 6.2 ± 1.2 | 0.006 |
CRP (mg/dL) | 12.9 (6.0–32.7) | 8.9 (5.1–26.7) | 15.2 (6.2–39.3) | 0.02 |
Uric acid (mg/dL) | 5.2 ± 1.6 | 4.9 ± 1.8 | 5.4 ± 1.4 | 0.18 |
Urea (mg/dL) | 30.1 ± 10.3 | 28.4 ± 6.8 | 31.7 ± 12.5 | 0.11 |
Creatinine (mg/dL) | 1.1 ± 0.4 | 1.0 ± 0.3 | 0.9 ± 0.3 | 0.2 |
miR-223 | 5.99 (3.02–11.16) | 4.4 (2.0–6.3) | 8.4 (4.5–14.9) | < 0.001 |