Sirtuin-1 level and gene polymorphisms in multiple sclerosis

Table 5 Linear regression analysis of different SIRT1 gene polymorphisms (rs2273773, rs7069102 and rs7895833) with clinical and laboratory parameters among MS sufferers

	SIRT1 genotypes
	rs2273773		rs7069102		rs7895833
	Β	P value	Β	P value	Β	P value
Expanded Disability Status Scale	0.052	0.7	0.146	0.3	0.108	0.5
Disease duration	− 0.258	0.5	− 0.264	0.7	− 0.177	0.14
Fasting blood glucose (mg/dl)	0.055	0.6	0.144	0.1	0.107	0.4
Cholesterol (mg/dl)	− 0.336	0.03*	− 0.246	0.1	− 0.411	0.04*
Triglycerides (mg/dL)	− 0.285	0.06	− 0.205	0.2	− 0.356	0.02*
High-density lipoprotein (mg/dL)	0.131	0.4	0.011	0.9	0.127	0.4
Low-density lipoprotein (mg/dL)	− 0.397	0.01*	− 0.303	0.04*	− 0.525	0.03*