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Table 1 Demographic and biochemical data of MS sufferers and control subjects

From: Sirtuin-1 level and gene polymorphisms in multiple sclerosis

 

MS sufferers

Control subjects

P value

Age (years)

37.5 ± 5.5

36.05 ± 5.46

0.14

Sex

   

Female

70 (58%)

66 (55%)

0.7

Male

50 (42%)

54 (45%)

 

Disease duration (years)

4.61 ± 3.33

–

–

Mean age at onset of MS

26.31 ± 7.86

–

–

Expanded Disability Status Scale

2.34 ± 1.33

–

–

Disease course

   

Relapsing–remitting

90 (75%)

–

–

Progressive

30 (25%)

  

Total cholesterol (mg/dL)

189 ± 38 180 ± 43 0.37

180 ± 43

0.08

Low-density lipoprotein (mg/dL)

86 ± 29

80 ± 27

0.09

High-density lipoprotein (mg/dL)

52 ± 5

53 ± 5

0.1

Triglycerides (mg/dL)

85 ± 22

79 ± 28

0.06

Serum SIRT1 level (ng/ml)

2.1 ± 0.25

3.4 ± 0.2

 < 0.0001**

  1. MS multiple sclerosis, SIRT1 Sirtuin1
  2. **p < 0.001: highly statistically significant