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Table 8 Testing the correlation between P300 variables and cognitive decline risk factors: TNF-α, COX-2, age, BMI and chronic diseases

From: Using 6-CIT, P300 encephalography, and pro-inflammation assessments for screening age-related cognitive decline and exploring associated risk factors in Egyptian elderly

Parameters

P300 latency

Amplitude

RT

TNF-α

COX-2

Age

BMI

CD

P300 latency

r

1

       

p

        

n

20

       

Amplitude

r

− 0.381

1

      

p

0.108

       

n

19

19

      

RT

r

− 0.250

− 0.008

1

     

P

0.303

0.974

      

n

19

18

19

     

TNF

r

0.276

0.023

− 0.068

1

    

P

0.301

0.935

0.810

     

n

16

15

15

89

    

COX

r

− 0.339

− 0.483

0.208

− 0.080

1

   

P

0.199

0.068

0.458

0.457

    

n

16

15

15

89

89

   

Age

r

− 0.609*

0.016

0.513

0.044

− 0.068

1

  

P

0.021

0.955

0.073

0.722

0.585

   

n

14

14

13

67

67

72

  

BMI

r

0.426

0.028

− 0.431

− 0.013

− 0.098

− 0.324**

1

 

P

0.128

0.924

0.141

0.917

0.429

0.010

  

n

14

14

13

67

67

63

71

 

CD

r

− 0.503

0.576*

0.309

0.075

− 0.173

0.076

0.003

1

P

0.056

0.031

0.282

0.528

0.140

0.540

0.983

 

n

15

14

14

74

74

67

65

79

  1. Significant or highly significant values are in bold
  2. RT: reaction to stimulus time; TNF-α: tumor necrosis factor alpha; COX-2: cyclooxygenase enzyme; BMI: body mass index; CD: chronic diseases
  3. *Correlation is significant at the 0.05 level (2-tailed), ** correlation is highly significant at the 0.01 level (2-tailed)