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Table 7 Testing the correlation between 6-CIT and its domains and cognitive decline risk factors: TNF-α, COX-2, age, BMI and chronic diseases

From: Using 6-CIT, P300 encephalography, and pro-inflammation assessments for screening age-related cognitive decline and exploring associated risk factors in Egyptian elderly

 

TNF-α

COX

Age

BMI

CD

TS

Q1

Q2

Q3

Q4

Q5

Q6

TNF-α

r

1

           

p

            

N

89

           

COX

r

− 0.080

1

          

p

0.457

           

N

89

89

          

Age

r

0.044

− 0.068

1

         

p

0.722

0.585

          

N

67

67

72

         

BMI

r

− 0.013

− 0.098

− 0.324**

1

        

p

0.917

0.429

0.010

         

N

67

67

63

71

        

CD

r

0.075

− 0.173

0.076

0.003

1

       

p

0.528

0.140

0.540

0.983

        

N

74

74

67

65

79

       

TS

r

− 0.039

− 0.033

0.032

− 0.176

− 0.206

1

      

p

0.739

0.775

0.794

0.152

0.078

       

N

76

76

69

68

74

81

      

Q1

r

− 0.016

− 0.051

− 0.111

0.027

0.081

0.024

1

     

p

0.890

0.658

0.364

0.825

0.492

0.832

      

N

77

77

69

68

74

81

82

     

Q2

r

− 0.039

0.119

0.126

− 0.082

− 0.063

0.175

− 0.018

1

    

p

0.741

0.306

0.303

0.506

0.597

0.118

0.875

     

N

76

76

69

68

74

81

81

81

    

Q3

r

− 0.067

− 0.116

− 0.099

0.193

− 0.126

0.329**

− 0.048

0.062

1

   

p

0.565

0.318

0.421

0.115

0.284

0.003

0.670

0.583

    

N

76

76

69

68

74

81

81

81

81

   

Q4

r

0.167

− 0.066

0.174

− 0.195

− 0.065

0.412**

− 0.035

0.118

− 0.134

1

  

p

0.150

0.569

0.153

0.110

0.584

0.000

0.757

0.294

0.233

   

N

76

76

69

68

74

81

81

81

81

81

  

Q5

r

− 0.048

− 0.007

0.227

− 0.375**

− 0.144

0.526**

0.035

0.050

− 0.262*

0.286**

1

 

p

0.679

0.955

0.060

0.002

0.223

0.000

0.756

0.659

0.018

0.010

  

N

76

76

69

68

74

81

81

81

81

81

81

 

Q6

r

− 0.027

0.072

− 0.087

− 0.106

− 0.036

0.537**

− 0.113

− 0.091

− 0.337**

0.115

0.199

1

p

0.815

0.538

0.478

0.390

0.763

0.000

0.315

0.417

0.002

0.307

0.074

 

N

76

76

69

68

74

81

81

81

81

81

81

81

  1. Significant or highly significant values are in bold
  2. Q1: What year is it?, Q2: What month is it?, Q3: Repeating a memory phrase, Q4: What time is it?, Q5: Count back from 20 till 1, Q6: Saying months in reverse
  3. CD: chronic disease; BMI: body mass index; TS: total score
  4. *Correlation is significant at the 0.05 level (2-tailed), ** correlation is highly significant at the 0.01 level (2-tailed)
  5. r correlation coefficient, P probability, N number