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Table 3 Relation between disease severity and the studied parameters

From: Neutrophil–lymphocyte ratio and platelet–lymphocyte ratio as predictors of MS severity: a retrospective cohort study

 

Mild

Moderate and severe

t

p

 

Mean ± SD

Mean ± SD

Age (year)

33.66 ± 6.17

31.55 ± 7.36

1.759

0.081

BMI

27.9 ± 4.25

30.74 ± 5.45

− 2.981

0.004*

Age of onset (year)

29.68 ± 5.44

27.93 ± 7.47

1.361

0.179

Hematocrit

40.64 ± 2.57

39.53 ± 3.2

1.976

0.053

NLR

2.57 ± 0.31

3.03 ± 0.52

− 5.206

 < 0.001**

WBCs

5.36 ± 0.82

5.6 ± 1.28

− 1.124

0.173

Platelet count

251.19 ± 34.15

262.48 ± 57.29

− 1.172

0.247

PLR

175.19 ± 27.94

234.6 ± 36.52

− 10.571

 < 0.001**

MLR

0.23 ± 0.04

0.23 ± 0.05

− 0.025

0.98

 

n = 110 (%)

n = 40 (%)

χ2

p

Sex

    

 Male

57 (51.8%)

3 (7.5%)

24.006

 < 0.001**

 Female

53 (48.2%)

37 (92.5%)

  

DMT

95 (86.4%)

5 (12.5%)

72.017

 < 0.001**

Type

    

 PPMS

1 (0.9%)

9 (22.5%)

Fisher

 < 0.001**

 RRMS

109 (99.1%)

31 (77.5%)

  
  1. BMI body mass index, NLR neutrophil–lymphocyte ratio, WBCs white blood cells, PLR platelet–lymphocyte ratio, MLR monocyte–lymphocyte ratio DMT disease-modifying therapy, PPMS primary progressive multiple sclerosis, RRMS relapsing–remitting multiple sclerosis
  2. *p < 0.05 is statistically significant
  3. **p ≤ 0.001 is statistically highly significant χ2 Chi square test t independent sample t test