Electrophysiological studies versus high-resolution nerve ultrasound in diagnosis of Guillain–Barré syndrome

Abou Hagar, Ahmed; Negm, Mohamed; Elshamly, Samer; Shehab, Osama; Mosallam, Walid; Abd El-Razek, Reda

doi:10.1186/s41983-024-00799-8

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 3 Nerve conduction study parameters among patients and controls

From: Electrophysiological studies versus high-resolution nerve ultrasound in diagnosis of Guillain–Barré syndrome

	Control (n = 37)	Patients		P₁	P₂	P₃
	Control (n = 37)	At presentation (n = 37)	On day 14 (n = 37)
	Mean ± SD	Mean ± SD	Mean ± SD
Median
DML (ms)	3.77 ± 0.25	3.82 ± 0.25	6.10 ± 1.79	^Up₁ = 0.376	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
CMAP (mV)	9.40 ± 3.09	8.97 ± 2.74	4.46 ± 2.01	^Up₁ = 0.642	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
MCV(m/s)	58.2 ± 6.20	56.9 ± 6.24	36.6 ± 11	^Up₁ = 0.341	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
F-wave latency (ms)	27.5 ± 1.89	36.7 ± 3.78	38.3 ± 4.22	^Up₁ < 0.001^*	^Up₂ < 0.001^*	^Zp₃ = 0.003^*
PL (ms)	2.94 ± 0.31	3.02 ± 0.32	4.59 ± 1.37	^Up₁ = 0.242	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
SNAP (µV)	32 ± 4.65	30.9 ± 4.51	16.4 ± 5.06	^Up₁ = 0.393	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
SCV(m/s)	59 ± 7.91	57.1 ± 7.38	35.9 ± 7.67	^Up₁ = 0.239,	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
Ulnar
DML (ms)	2.78 ± 0.27	2.89 ± 0.24	5.32 ± 2.12	^Up₁ = 0.090	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
CMAP (mV)	9.76 ± 2.43	8.95 ± 1.51	5.51 ± 1.59	^Up₁ = 0.258	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
MCV (m/s)	57.5 ± 5.81	55.9 ± 5.67	36.4 ± 10.8	^Up₁ = 0.211	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
F-wave latency (ms)	28.0 ± 1.93	36.5 ± 3.47	38.9 ± 4.38	^Up₁ < 0.001^*	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
PL (ms)	2.69 ± 0.23	2.83 ± 0.35	4.32 ± 1.15	^Up₁ = 0.126	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
SNAP (µV)	32.9 ± 6.41	32.7 ± 6.08	15.8 ± 5.65	^Up₁ = 0.880	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
SCV (m/s)	58.2 ± 7.14	56.2 ± 4.57	36 ± 7.29	^Up₁ = 0.214	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
Tibial
DML (ms)	4.40 ± 0.58	4.56 ± 0.55	7.09 ± 1.62	^Up₁ = 0.147	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
CMAP (mV)	9.64 ± 5.35	8.58 ± 4.07	4.31 ± 1.45	^tp₁ = 0.343	^tp₂ < 0.001^*	^t1p₃ < 0.001^*
MCV(m/s)	48.8 ± 3.22	47.2 ± 3.75	32.97 ± 7.98	^Up₁ = 0.030^*	^Up₂ < 0.001^*	^Zp₃ < 0.001^*
F-wave latency (ms)	48.5 ± 2.95	58.3 ± 3.79	59.6 ± 4.11	^Up₁ < 0.001^*	^Up₂ < 0.001^*	^Zp₃ = 0.070
Sural
PL (ms)	3.57 ± 0.35	3.66 ± 0.36	3.71 ± 0.34	^Up₁ = 0.255	^Up₂ = 0.07	^Zp₃ = 0.43
SNAP (µV)	12.3 ± 4.21	11.7 ± 3.59	11.35 ± 2.9	^Up₁ = 0.614	^Up₂ = 0.268	^Zp₃ = 0.626
SCV(m/s)	53.4 ± 5.46	52.6 ± 4.93	51.8 ± 4.74	^Up₁ = 0.473	^Up₂ = 0.151	^Zp₃ = 0.083

SD standard deviation, U Mann–Whitney test, Z Wilcoxon signed ranks test, p₁ p value for comparing between the patients at presentation and controls, p₂ p value for comparing between the patients on day 14 and controls, p₃ p value for comparing between the patients at presentation and on day 14, DML distal motor latency, CMAP compound muscle action potential, MCV motor conduction velocity, PL peak latency, SNAP sensory nerve action potential, SCV sensory conduction velocity, ms millisecond, mV millivolt, m/s meter per second, µV microvolt
^*Statistically significant at p ≤ 0.05

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