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Table 8 Comparison between epileptic children on monotherapy, polytherapy and control group regarding thyroid and lipid parameters

From: Effect of anti-epileptic drugs usage on thyroid profile in Egyptian epileptic children

 

Treatment

ANOVA

Tukey's test

Monotherapy

Polytherapy

Control

Mean

 ± 

SD

Mean

 ± 

SD

Mean

 ± 

SD

F

P-value

I&II

I&III

II&III

T4

0.967

 ± 

0.438

0.881

 ± 

0.551

1.752

 ± 

0.159

103.243

 < 0.001*

0.408

 < 0.001*

 < 0.001*

TSH

2.277

 ± 

1.753

1.761

 ± 

1.688

0.885

 ± 

0.428

18.839

 < 0.001*

0.065

 < 0.001*

 < 0.001*

Total cholesterol

189.868

 ± 

30.726

190.570

 ± 

37.650

85.641

 ± 

18.787

312.972

 < 0.001*

0.988

 < 0.001*

 < 0.001*

Triglyceride

120.842

 ± 

35.321

118.772

 ± 

33.101

110.474

 ± 

23.744

2.412

0.092

0.910

0.099

0.218

HDL-cholesterol

40.461

 ± 

10.523

40.785

 ± 

11.283

57.372

 ± 

4.358

84.981

 < 0.001*

0.974

 < 0.001*

 < 0.001*

LDL-cholesterol

126.276

 ± 

29.978

129.430

 ± 

32.638

78.269

 ± 

13.275

89.804

 < 0.001*

0.743

 < 0.001*

 < 0.001*

  1. TSH thyroid stimulating hormone, HDL high-density lipoprotein, LDL low-density lipoprotein, SD standard deviation, ANOVA analysis of variance. P value < 0.05 statistically significant, P value < 0.01 statistically highly significant