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Table 12 Comparison between different groups of polytherapy and control group regarding thyroid and lipid parameters

From: Effect of anti-epileptic drugs usage on thyroid profile in Egyptian epileptic children

 

Polytherapy

ANOVA

Two I

Three II

Four III

Control IV

Mean

 ± 

SD

Mean

 ± 

SD

Mean

 ± 

SD

Mean

 ± 

SD

F

P-value

T4

0.909

 ± 

0.613

0.820

 ± 

0.455

0.963

 ± 

0.415

1.752

 ± 

0.159

59.917

 < 0.001*

TSH

1.895

 ± 

1.822

1.648

 ± 

1.482

0.913

 ± 

1.285

0.885

 ± 

0.428

7.514

 < 0.001*

Total cholesterol

186.229

 ± 

40.806

199.852

 ± 

29.107

180.000

 ± 

46.904

85.641

 ± 

18.787

165.784

 < 0.001*

Triglyceride

115.729

 ± 

30.208

124.630

 ± 

35.671

115.750

 ± 

51.913

110.474

 ± 

23.744

1.644

0.181

HDL-cholesterol

40.375

 ± 

9.890

41.556

 ± 

13.568

40.500

 ± 

13.178

57.372

 ± 

4.358

48.558

 < 0.001*

LDL-cholesterol

126.458

 ± 

34.928

134.963

 ± 

28.502

127.750

 ± 

33.500

78.269

 ± 

13.275

55.597

 < 0.001*

Tukey's test

 

I&II

I&III

I&IV

II&III

II&IV

III&IV

T4

0.804

0.994

 < 0.001*

0.915

 < 0.001*

0.001*

TSH

0.838

0.421

 < 0.001*

0.682

0.031*

1.000

Total cholesterol

0.227

0.978

 < 0.001*

0.595

 < 0.001*

 < 0.001*

Triglyceride

0.576

1.000

0.754

0.940

0.129

0.984

HDL-cholesterol

0.941

1.000

 < 0.001*

0.996

 < 0.001*

0.001*

LDL-cholesterol

0.491

1.000

 < 0.001*

0.949

 < 0.001*

0.001*

  1. TSH thyroid stimulating hormone, HDL high-density lipoprotein, LDL low-density lipoprotein, SD standard deviation, ANOVA analysis of variance. P value < 0.05 statistically significant, P value < 0.01 statistically highly significant