Table 1 Stages in progression of Alzheimer’s disease [89]
From: Targeting the molecular web of Alzheimer’s disease: unveiling pathways for effective pharmacotherapy
No. | Stages | Observations |
|---|---|---|
1 | No impairment | Appears normal Stays mentally and physically active No treatment is necessary |
2 | Very mild decline | Will begin to experience forgetfulness No treatment necessary |
3 | Mild decline | Will begin to notice change and decline in function AD can now be diagnosed |
4 | Moderate decline | Thinking and reasoning become more obvious and new issues appear Clear signs and symptoms of AD are seen |
5 | Moderately severe decline | May experience significant confusion and become agitated Begins to require help with normal day-to-day activities |
6 | Severe decline | May begin to wander Requires assistance and/or reminders with many of the activities of daily life Requires constant supervision |
7 | Very severe decline | Loss of the ability to respond to the environment or communicate Loss of movement and communication Disease complications may result in death |