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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 2 miRNA correlation with clinical and radiological characteristics

From: Micro-RNA in a sample of Egyptian patients with incidental cerebral small vessel disease

 

miRNA-451a

miRNA-486-5p

miRNA-502-3p

Age

   

 Point biserial

− 0.0313

0.42*

0.152

 Sig.

0.92

0.01

0.421

Age of onset

   

 Point biserial

− 0.31

0.43*

0.134

 Sig.

0.09

0.01

0.479

Duration of illness

   

 Point biserial

0.16

− 0.39*

− 0.138

 Sig.

0.41

0.03

0.466

MoCA

   

 Point biserial

0.224

0.093

− 0.191

 Sig.

0.233

0.62

0.310

BDI (total score)

   

 Point biserial

0.006

− 0.159

0.053

 Sig.

0.97

0.40

0.779

Berg Balance Score

   

 Point biserial

− 0.089

0.012

− 0.193

 Sig.

0.64

0.95

0.306

10MWT self-selected velocity

   

 Point biserial

− 0.010

− 0.017

− 0.23

 Sig.

0.96

0.93

0.212

ICIQ-SF

   

 Point biserial

− 0.43

− 0.227

0.045

 Sig.

0.86

0.226

0.811

SVD score

   

 Point biserial

− 0.43

0.114

0.203

 Sig.

0.012

0.55

0.279

  1. Bold values indicate significant values
  2. miRNA micro ribonucleic acid, MoCA Montreal Cognitive Assessment, BDI Beck Depression Inventory, 10MWT 10-meter walk test, ICIQ-SF The Arabic International Consultation on Incontinence Questionnaire-Short Form Scale, SVD small vessel disease
  3. *p value is significant if < 0.05
  4. Correlation with miRNA-409-3p could not be done due to statistical limitation
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