Optical coherence tomography and optical coherence tomography angiography in multiple sclerosis

Table 2 Comparison of SD-OCT parameters between eyes with optic neuritis (ON) (group 1a), eyes without ON (group 1b) and controls (group 2)

SD-OCT parameters	Eyes with ON (mean ± SD)	Eyes without ON (mean ± SD)	Controls (mean ± SD)	Eyes with ON vs. controls (p value)	Eyes without ON vs. controls (p value)
Average RNFL (µm)	84.60 ± 9.8	89.51 ± 12.75	104.3 ± 8.3	< 0.001*	< 0.001*
Superior RNFL (µm)	85.68 ± 10	91.60 ± 13.3	104.2 ± 8.1	< 0.001*	< 0.001*
Inferior RNFL (µm)	83.44 ± 10.5	87.43 ± 12.96	103.1 ± 9	< 0.001*	< 0.001*
Average GCC (µm)	81.73 ± 12.1	88.57 ± 11.69	101.8 ± 4.4	< 0.001*	< 0.001*
Superior GCC (µm)	80.85 ± 11.7	87.91 ± 11.56	101.2 ± 4.7	< 0.001*	< 0.001*
Inferior GCC (µm)	82.83 ± 12.64	89.03 ± 12.34	101.8 ± 4.9	< 0.001*	< 0.001*
FLV (%)	4.74 ± 3.56	3.14 ± 2.73	0.68 ± 0.24	0.001*	0.001*
GLV (%)	14.38 ± 10.85	8.81 ± 8.6	1.2 ± 0.5	< 0.001*	< 0.001*

SD-OCT spectral domain optical coherence tomography, SD standard deviation, RNFL retinal nerve fiber layer, GCC ganglion cell complex, FLV focal loss volume, GLV global loss volume