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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 5 Comparison of frequency of DGM hyperechogenicity between the MS patients’ and control groups

From: Validation of brain parenchyma sonography as a marker of neurodegeneration in multiple sclerosis

DGM hyperechogenicity

(cm2)

RRMS group

(n = 48)

Control group

(n = 57)

p-value

Count

Frequency%

Count

Frequency %

SN

 ≥ 75th percentile

17

35.4

14

24.56

0.25

 ≥ 90th percentile

11

22.9

6

10.53

0.09

RN

 ≥ 75th percentile

25

52.1

14

24.56

0.004*

 ≥ 90th percentile

18

37.5

6

10.5

0.001*

Th

 ≥ 75th percentile

8

16.67

14

24.56

0.45

 ≥ 90th percentile

5

10.42

6

10.50

1.0

  1. DGM deep grey matter, RRMS relapsing–remitting multiple sclerosis, n number, cm2 centimeters square, SN substantia nigra, RN red nucleus, Th. thalamus, H1 moderate hyperechogenicity (75th–90th percentile of the larger of bilaterally measured echogenic sizes), H2 marked hyperechogenicity (> 90th percentile of the larger of bilaterally measured echogenic sizes), total = values > 75th percentiles
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