Validation of brain parenchyma sonography as a marker of neurodegeneration in multiple sclerosis

Table 3 Correlation between ventricular diameter, as assessed by TCS and EDSS functional steps in subjects with MS (n = 48)

EDSS FS	3rd ventricle (cm)		Rt. FH (cm)		Lt. FH (cm)
EDSS FS	r	p- value	r	p- value	r	p- value
Visual	− 0.14	0.34	− 0.13	0.4	− 0.08	0.59
Brainstem	0.23	0.11	− 0.07	0.63	0.03	0.83
Pyramidal	0.15	0.33	0.25	0.1	0.35*	0.02*
Cerebellar	0.23	0.05	0.165	0.266	0.165	0.268
Sensory	0.015	0.919	− 0.086	0.564	− 0.052	0.728
Bowel and blabber	0.123	0.404	0.262	0.075	0.356*	0.014*
Ambulation	0.166	0.428	0.190	0.364	0.365	0.073
cerebral	0.028	0.848	0.051	0.732	0.093	0.533

TCS transcranial sonography, EDSS Expanded Disability Status Score, EDSS FS Expanded Disability Status Scale Functional Step, MS multiple sclerosis, 3rd third, cm centimeters, Rt. right, Lt. left, FH frontal horn, r correlation coefficient
^*Correlation is significant at the 0.05 level (2-tailed)