Validation of brain parenchyma sonography as a marker of neurodegeneration in multiple sclerosis

Table 2 Relation of clinical data to TCS parameters of brain atrophy in the MS patients’ group (n = 48)

Clinical parameter	3rd ventricle (cm)		Rt. FH (cm)		Lt. FH (cm)
Clinical parameter	r	p- value	r	p- value	r	p- value
Age (ys)	0.15	0.3	0.19	0.21	0.26	0.08
Age at onset (ys)	0.02	0.88	0.15	0.31	0.08	0.61
Disease duration (ms)	0.29	0.1	0.1	0.51	0.32*	0.03*
Total EDSS	0.48**	< 0.0001**	0.24	0.11	0.39	0.007

TCS transcranial sonography, MS multiple sclerosis, n number, 3rd third, cm centimeters, Rt. right, Lt. left, FH frontal horn, r correlation coefficient, ys years, ms months, EDSS Expanded Disability Status Scale
^*Correlation is significant at the 0.05 level (2-tailed)
^**Correlation is significant at the 0.01 level (2-tailed)