Fig. 4From: Synaptic microenvironment and altered state of consciousness in schizophrenia: a possible link between synapse geometry and orchestrated objective reduction theoryMicrotubules isolation and quantum computation. At healthy condition binding the ligand (glutamate) to polySia leads to spatio-temporal decoherence state of polySia(s) at post-synaptic membrane which result into trigger release of noncovalent energy by gel like structure and decoupling of Actin and MAP. These events lead to MTs isolation from outside of neuron and spin currents interact and compute along spiral lattice pathways. Geometric alteration of synapse may affect the defined physiologic range of polySia vibrational state at post-synaptic membrane, hindering actin coupling–decoupling, thus impeding orchestrated ORBack to article page