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Table 7 Relation between Bamford and TOAST classifications and stroke severity and osteoprotegerin (OPG) rs3102735 polymorphism

From: Role of osteoprotegerin rs3102735 gene polymorphism in acute ischemic stroke patients

 

Bamford classification

χ2

MCp-value

TACS (n = 19)

PACS (n = 24)

POCS (n = 4)

LACS (n = 3)

OPG rs3102735 polymorphism

 CC

14

18

3

1

2.377

0.481

 CT

4

6

1

2

3.025

0.396

 TT

1

0

0

0

3.523

0.524

 

TOAST classification

  

LAA (n = 29)

SVD (n = 21)

CE (n = 0)

Undetermined (n = 0)

OPG rs3102735 polymorphism

 CC

20 (70.0%)

14 (66.7%)

0

0

0.029

1.000

 CT

8 (27.6%)

5 (23.8%)

0

0

0.009

0.923

 TT

1 (3.4%)

2 (9.5%)

0

0

0.669

1.000

 

Stroke severity (NIHSS)

  

Mild

Moderate

Moderate to severe

Severe

OPG rs3102735 polymorphism

 CC

0

24 (54.5%)

4 (66.7%)

0

2.367

0.186

 CT

0

13 (29.5%)

2 (33.3%)

0

2.927

FEp = 0.117

 TT

0

7 (15.9%)

0 (0%)

0

3.573

FEp = 0.088

  1. χ2 Chi square test, MC Monte Carl, FE Fisher Exact, OPG osteoprotegerin, C cytosine nucleotide, T thiamine nucleotide, TOAST Trial of Org 10172 in Acute Stroke Treatment, TACS total anterior circulation stroke, LAA large artery atherosclerosis, PACS partial anterior circulation stroke, SVD small vessel disease, POCS posterior circulation syndrome, CE cardioembolic, NIHSS National Institutes of Health Stroke Scale, LACS lacunar syndrome