The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 2 Comparison between the patients and the control groups in psychometric tests and radiological data

From: Could thalamic biochemical changes correlate to cognitive impairment in idiopathic generalized epilepsy?

	Patients (n = 30)	Control (n = 30)	P-value
	Mean ± SD	Mean ± SD
Psychometric tests
IQ test	100.4 ± 4.1	103.5 ± 3.7	0.003
DST	7.03 ± 0.99	7.9 ± 0.89	0.001
WMS-R	26.7 ± 5.4	34.5 ± 5.6	< 0.001
CDT	23.9 ± 3.9	26 ± 2.3	0.02
Trail-making A	41.3 ± 7.5	35.2 ± 7.8	0.003
Trail-making B	111.2 ± 14.5	103.4 ± 11.1	0.02
COWAT-phenomic	34.2 ± 5.7	36.5 ± 5.5	0.1
COWAT-semantic	11.8 ± 1.9	12.5 ± 2.2	0.2
Radiological data
NAA
Right thalamus	13.3 ± 3.5	15.6 ± 2.2	0.004
Left thalamus	13.9 ± 3.6	15.7 ± 3.1	0.06
Choline
Right thalamus	2.3 ± 0.79	2.4 ± 0.76	0.6
Left thalamus	2.3 ± 0.68	2.4 ± 0.95	0.7
Creatine
Right thalamus	8.4 ± 2.4	8.1 ± 1.6	0.6
Left thalamus	8.5 ± 2.6	7.4 ± 2.3	0.09
NAA/choline ratio
Right thalamus	6.3 ± 2.3	7 ± 2.3	0.2
Left thalamus	6.6 ± 2.6	7.4 ± 2.9	0.2
NAA/creatine ratio
Right thalamus	1.7 ± 0.66	1.9 ± 0.48	0.2
Left thalamus	1.8 ± 0.71	2.4 ± 1.3	0.01
Choline/creatine ratio
Right thalamus	0.30 ± 0.14	0.31 ± 0.14	0.7
Left thalamus	0.29 ± 0.11	0.39 ± 0.42	0.2

Bold indicates *p < 0.05 is considered significant
IQ intelligence quotient, DST digit span test, CDT cube drawing test, COWAT controlled oral word association test, NAA N-acetyl aspartate

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