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Table 3 Relationship between socio-demographic characteristics and QOLIE-31 domains

From: Determinants of quality of life in Nigerian female patients with epilepsy on carbamazepine and levetiracetam monotherapy

Variables

Seizure

worry

Overall quality

of life

Emotional

well-being

Energy

Cognitive

functioning

Medication

effects

Social

functioning

Age range(years)a

 15–25

45.31(18.48)c

59.33(24.25)d

51.18(14.37)

50.34(9.73)

46.92(18.62)

55.62(23.11)

51.41(22.40)

 26–35

51.45(15.40)

47.17(16.41)

46.00(11.35)

50.50(9.41)

45.82(12.53)

44.14(24.69)

45.34(17.98)

 36–45

56.93(16.25)

55.00(20.60)

53.38(11.92)

48.46(9.98)

48.42(15.14)

47.54(26.54)

49.85(19.55)

 p value

0.023*

0.058

0.087

0.679

0.834

0.123

0.450

Level of educationa

 Primary

47.63(17.74)

47.10(14.19)e

49.94(10.83)

47.42(6.69)

42.46(14.55)e

42.47(19.60)

41.62(14.93)e

 Secondary

45.45(18.09)

51.94(20.58)f

47.31(13.70)

48.86(9.78)

42.53(15.29)g

53.09(22.33)

45.74(17.73))f

 Tertiary

56.31(14.91)

61.12(24.83)

52.41(12.44)

52.24(11.07)

53.90(14.34)

50.74(30.81)

57.39(22.50)

 Postgraduate

63.40(13.28)

81.00(22.12)

59.20(21.98)

59.00(9.62)

66.06(13.21)

72.23(17.35)

72.60(26.17)

 p value

0.020*

0.002*

0.180

0.032*

0.000*

0.056

0.001*

Ethnicitya

 Yoruba

50.69(17.48)

53.99(21.87)

50.20(13.21)

49.72(10.04)

46.69(15.95)

48.74(25.18)

49.36(20.07)

 Hausa

43.00(17.99)

54.50(18.91)

48.00(9.38)

49.00(4.18)

49.00(21.86)

59.45(12.68)

48.44(30.27)

 Igbo

48.44(19.81)

62.92(21.88)

52.00(15.80)

53.33(6.06)

49.68(13.53)

62.04(24.20)

47.17(20.24)

 p value

0.619

0.625

0.883

0.663

0.871

0.309

0.965

Age of onset (years)a

 1–15

43.31(16.14)

47.99(16.29)

45.89(11.29)

48.75(9.66)

42.57(13.76)

45.37(22.54)

44.78(14.02)

 16–30

50.79(17.53)

57.10(24.85)

51.52(14.36)

51.19(9.36)

48.47(16.95)

53.48(24.68)

50.95(23.43)

 31–45

59.87(15.37)

60.83(21.32)

54.67(12.02)

49.29(10.52)

51.81(16.71)

52.53(22.95)

52.53(22.95)

 46 and above

68.00(0.00)

52.50(0.00)

56.00(0.00)

50.00(0.00)

42.22(0.00)

63.00(0.00)

63.00(0.00)

 p value

0.003*

0.127

0.071

0.723

0.164

0.314

0.394

Depressionb

 Present

49.49(17.75)

52.30(20.41)

49.30(13.21)

49.01(9.10)

45.43(15.59)

47.50(24.10)

47.17(19.95)

 Absent

54.37(16.09)

68.39(24.55)

55.71(11.36)

55.36(11.34)

56.49(15.58)

65.88(23.81)

61.57(19.33)

 p value

0.337

0.009*

0.090

0.022*

0.016*

0.009*

0.013*

Drugs

 CBM

53.59(15.00)

41.66(11.09)

46.16(11.09)

47.10(10.22)

42.23(10.22)

33.98(20.34)

39.93(12.60)

 LTM

46.75(19.30)

67.45(20.34)

54.24(13.81)

52.70(9.10)

51.73(19.12)

66.17(17.29)

58.44(22.51)

 Mean SD

50.17(17.54)

54.56(21.64)

50.20(13.11)

49.90(9.64)

46.98(15.98)

50.07(24.79)

49.18(20.39)

 F

3.915

54.812

10.405

9.130

9.593

72.672

25.750

 p value

0.051

0.000*

0.002*

0.003*

0.003*

0.000*

0.000*

  1. aANOVA with Tukey’s HSD
  2. bIndependent t-test
  3. c15–25 significantly different at p < 0.05 compared to ages 36–45 years
  4. d15–25 significantly different at p < 0.05 compared to ages 26–35 years
  5. ePrimary significantly different at p < 0.05 compared to tertiary and Postgraduate
  6. fSecondary significantly different at p < 0.05 compared to Postgraduate
  7. gSecondary significantly different at p < 0.05 compared to Tertiary
  8. pFocal significantly different at p < 0.05 compared to generalized
  9. *Statically significant, CBM carbamazepine, LTM levetiracetam