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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 1 relationship between socio-demographic and clinical characteristics and QOLIE-TS

From: Determinants of quality of life in Nigerian female patients with epilepsy on carbamazepine and levetiracetam monotherapy

Variables

Categories

n(%)

QOLIE total score

Mean (S.D)

Statistics

Df

p-Value

Age range(years)

15–25

44(44)

50.78(15.55)

F = 0.923

2, 97

0.401

 

26–35

30(30)

46.90(10.25)

   
 

36–45

26(26)

51.05(12.85)

   
 

Mean age ± SD (29.07 ± 7.55)

     

Highest level of education

Primary

31(31)

45.06(8.65)

F = 7.872

3, 96

0.000*

 

Secondary

35(35)

46.55 (12.15)

   
 

Tertiary

29(29)

55.32 (14.53)

   
 

Postgraduate

5(5%)

67.62 (17.27)

   

Ethnicity

Yoruba

89(89)

49.34 (16.28)

F = 0.098

2, 97

0.906

 

Hausa

5(5)

52.06 (14.60)

   
 

Igbo

6(6)

49.54 (13.38)

   

Duration of epilepsy

 < 2years

23(23)

55.69 (15.26)

t = 2.503

98

0.014*

 

 ≥ 2years

77(77)

47.89 (12.41)

   

Age of onset (years)

1–15

34(34)

45.18(9.46)

F = 2.394

3, 96

0.073

 

16–30

42(42)

51.32 (15.11)

   
 

31–45

21(21)

54.02 (14.43)

   
 

46 and above

3(3)

52.49(0.00)

   
 

Mean Age ± SD (20.01 ± 11.57)

     

Depression

Absent

86(86)

48.16 (12.62)

t = − 2.925

98

0.004*

 

Present

14(14)

59.08 (15.01)

   

Family history of epilepsy

Yes

14(14)

44.08(9.28)

t = − 1.698

98

0.093

 

No

86(86)

50.60 (13.84)

   

Last episode of seizure

Nil

3(3)

50.63(2.39)

F = 1.179

3, 96

0.322

 

 < 6 months

60(60)

47.81 (13.86)

   
 

6 months–1 year

30(30)

53.43 (13.84)

   
 

2–5 years

7(7)

49.28(7.92)

   

Aetiology

Structural

55(55)

48.67 (13.11)

F = 1.179

3, 96

0.322

 

Metabolic

3(3)

63.46 (16.06)

   
 

Immune

1(1)

52.53 (0.00)

   
 

Unknown

41(41)

49.96 (13.67)

   

Type of AED

CBM

50(50)

43.50 (5.50)

t = − 5.157

98

0.000*

 

LTM

50(50)

55.87 (16.04)

   

Seizure type

Focal

16(16)

47.86 (13.77)

F = 0.555

3, 96

0.646

 

Generalized

32(32)

52.19 (14.14)

   
 

FBTC

40(40)

48.75 (12.69)

   
 

Unknown/unclassified

12(12)

48.53 (14.40)

   

EEG frequency

Fast

42(42)

54.28 (16.01)

t = 3.027

98

0.003*

 

Slow

58(58)

46.36 (10.14)

   

Epileptiform pattern

Nil

14(14)

50.18 (14.65)

F = 1.899

2, 97

0.155

 

Focal

42(42)

52.46 (14.28)

   
 

Generalized

44(44)

46.88 (11.89)

   
  

14(14)

43.60 (7.86)

t = − 1.846

  
  1. QOLIE Quality of life in Epilepsy Inventory, AED anti-epileptic drug, EEG electroencephalography, Df degree of freedom, n number, t Student’s independent value, F one-way analysis of variance (ANOVA) value, CBM carbamazepine, LTM levetiracetam
  2. *Statistically significant
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