The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 2 Comparison of MMN responses (using both tone and speech stimuli) between different study subgroups

From: Mismatch negativity as an early biomarker of cognitive impairment in schizophrenia

		Ia	IIa	Ib	IIb	P₁	P₂	P₃
Tone stimuli
Amplitude
Rt Ear	Range	− 7.6– − 4.9	− 2.8– − 1.2	− 7.6– − 1.3	− 3.0– − 0.7
Rt Ear	Mean ± SD	− 3.9 ± 2.7	− 2.1 ± 0.6	− 4.7 ± 2.1	− 1.3 ± 1.2	0.019*	0.001*	0.035*
Lt Ear	Range	− 5.0– − 1.2	− 4.0– − 0.5	− 6.0– − 1.2	− 2.0– − 0.3
Lt Ear	Mean ± SD	− 3.2 ± 1.3	− 1.8 ± 1.1	− 3.0 ± 1.6	− 0.5 ± 0.9	0.005*	0.001*	0.001*
Latency
Rt Ear	Range	113–168	145–230	113.0–195	164.0–230
Rt Ear	Mean ± SD	146.1 ± 12.8	159.6 ± 31	147.1 ± 18.6	191.9 ± 21.6	0.130	0.001*	0.002*
Lt Ear	Range	120.0–170	150–200	120.0–170	160.0–234
Lt Ear	Mean ± SD	149.1 ± 14.7	169.1 ± 19.4	148.9 ± 17.2	191.4 ± 24.9	0.448	0.001*	0.011*
Speech stimuli
Amplitude
Rt Ear	Range	− 6.4– − 1.2	− 3.6– − 2.0	− 8.6– − 1.4	− 3.7– − 0.9
Rt Ear	Mean ± SD	− 3.3 ± 2.0	− 2.9 ± 0.5	− 4.3 ± 2.1	− 1.9 ± 1.0	0.004*	0.001*	0.003*
Lt Ear	Range	− 5.0– − 1.4	− 3.2– − 0.7	− 5.0– − 1.6	− 2.8– − 1.0
Lt Ear	Mean ± SD	− 3.4 ± 1.0	− 2.1 ± 0.7	− 3.0 ± 1.0	− 1.5 ± 0.4	0.001*	0.001*	0.010*
Latency
Rt Ear	Range	130.0–165	160–190	114.0–184	150.0–183
Rt Ear	Mean ± SD	141.6 ± 10.2	176.3 ± 9.0	152.0 ± 14.7	188.0 ± 18.7	0.001*	0.001*	− 2.100
Lt Ear	Range	120.0–160	139–220	134.0–190	149.0–245
Lt Ear	Mean ± SD	147 ± 12.6	179.9 ± 19.2	149.6 ± 15.4	201.4 ± 30.3	0.001*	0.001*	− 2.223

P₁ P value of Ia–IIa, difference, P₂ P value of Ib–IIb difference, P₃ P value of IIa–IIb difference
*Statistically significant

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