The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 1 Comparison of psychometric tests between different study subgroups

From: Mismatch negativity as an early biomarker of cognitive impairment in schizophrenia

	Ia	IIa	Ib	IIb	P₁	P₂	P₃
MMSE
Range	29.0–30.0	20.0–23.0	29.0–30.0	10.0–17.0	0.001*	0.001*	0.001*
Mean ± SD	29.7 ± 0.5	21.9 ± 1.1	29.8 ± 0.4	14.1 ± 2.9	0.001*	0.001*	0.001*
Digit span test
Range	11.0–29.0	8.0–12.0	11.0–25.0	8.0–10.0	0.018*	0.001*	0.001*
Mean ± SD	13.5 ± 4.3	10.5 ± 1.3	18.9 ± 9.7	8.7 ± 0.9	0.018*	0.001*	0.001*
Digit symbol test
Range	29.0–44.0	21.0–30.0	29.0–45.0	10.0–23.0	0.001*	0.001*	0.001*
Mean ± SD	38.5 ± 5.0	24.7 ± 3.7	36.7 ± 5.1	12.4 ± 3.2	0.001*	0.001*	0.001*
TMT
Range	85.0–100	170–200	88.0–130	190–300	0.001*	0.001*	0.001*
Mean ± SD	89.6 ± 4.4	180.2 ± 8.9	106.9 ± 15	245.6 ± 45.3	0.001*	0.001*	0.001*

MMSE Mini mental state examination, TMT trait making test, Subgroup (Ia) young control subjects, Subgroup (IIa) early schizophrenic patients, Subgroup (Ib) old control subjects, Subgroup (IIb) chronic schizophrenic patients, P₁: P values between early schizophrenic patients and matched control subgroup, P₂: P values between chronic schizophrenic patients and matched control subgroup, P₃: P values between early and chronic schizophrenic patients
*Statistically significant

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