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Table 2 Characteristics of outcome measures of included studies

From: Efficacy and safety of botulinum toxin-A in writer’s cramp: a systematic review, meta-analysis, and meta-regression

Study

Evaluation parameters

Writing speed

WCRS score

  

Experimental

Control

Experimental

Control

Rajan, 2021

WCRS, WS, PGIC, Total power on spectrum analysis, Grip strength via dynamometer, Fahn-Tolosa-Marin Tremor Rating Scale (A, B, C)

5.0 ± 33.33 (Pre)

5.0 ± 33.26 (Post)

4.3 ± 29.0 (Pre)

4.3 ± 3.33 (Post)

11.6 ± 1.8 (Pre)

7.2 ± 1.2 (Post)

11.2 ± 1.7 (Pre)

8.9 ± 1.3 (Post)

Park, 2019

Patient related subjective scoring score, WCRS, WCIS, WCDS,

Handgrip strength, kinetic parameters

NA

NA

8.3 ± 2.8 (Pre)

11.5 ± 3 (Post)

NA

Srivantichapoo m, 2016

Active ROM: forearm, wrist, fingers, DDS Handwriting Scale

NA

NA

NA

NA

Likachev, 2016

WCRS, Symptom Severity Scale, FSS

NA

NA

10 ± 3.53 (Pre)

8 ± 2.82 (Post)

NA

Jackman, 2016

UDRS, Dystonia Movement, Disability Scale DMDS, WCRS, Kinematic analysis

NA

NA

8.5 ± 0.706

5 ± 0.706

Zeuner, 2013

Force sensor, DDS, WCRS

NA

NA

10.37 ± 5.68 (Pre)

8.90 ± 7.13 (Post)

NA

Contarino, 2007

Sensory Evoked Potentials SEP, Writing speed

2.1 ± 1.9/mean change

0.3 ± 1.4 mean change

NA

NA

Marion, 2003

Subjective Handwriting assessment

NA

NA

NA

NA

Kruisdijk, 2007

VAS, FSS, WCRS, Writing speed

7.59 ± 2.80 (Pre) 9.00 ± 

2.28 (Post)

7.93 ± 3.20 (Pre)

8.20 ± 2.90 (Post)

4.50 ± 1.96 (Pre)

2.20 ± 1.88 (Post)

4.47 ± 1.184 (Pre)

3.68 ± 1.16 (Post)

Djebbdari, 2005

Burke-Fahn-Marsden Scale,

Self-assessment on handwriting quality, DDS

NA

NA

NA

NA

Behari, 1999

Ease of writing, abnormal posture, pain, WS

15.75 + − 5.28 (Pre)

18.92 + 4.9 (Post)

NA

NA

NA

Chen, 1999

Self-reported (benefit scale, VAS, weakness), WCRS, writing speed, writing quality

scale

1.47 ± 1.8 (Pre)

1.38 ± 1.3 (Post)

NA

4.9 ± 1.1 (Pre

7.8 ± 0.7 (Post)

NA

Wissel, 1996

WCRS, writing speed, MRC Scale, video recording of writing

1.1 ± 0.5 (Pre)

0.8 ± 0.6 (Post)

NA

9.1 ± 4.5 (Pre)

6.6 ± 4.1 (Post)

NA

Turjanski, 1996

Subjective handwriting

assessment, fluency, duration of writing

NA

NA

NA

NA

Cole, 1995

MRC, timed writing, writing errors

NA

NA

NA

NA

Tsui, 1993

Writing speed, Gibson’s maze, accuracy pen control

Subjective

NA

NA

NA

Rivest, 1991

Subjective handwriting assessment, fluency, duration of writing

NA

NA

NA

NA

Poungvarin, 1991

Subjective pain, hand tremor assessment in writing

NA

NA

NA

NA

Cohen, 1989

MRC, EMG

NA

NA

NA

NA

  1. VAS visual analogue scale, SEP sensory evoked potentials, ROM range of motion, DDS dystonia disability scale, WCRS writer’s cramp rating scale, WS writing speed, WCIS writer’s cramp impairment scale, WCDS writer’s cramp disability scale, MRC Medical Research Council, FSS functional status scale, NA not applicable