Childhood depression and oxidative stress

Table 2 Cut-off values of CDI, MDA, SOD, TAS, TOS, OSI and sensitivity, specificity, PPV and NPV rates in diagnosing MDD

	AUC	Std. error	p	95% confidence interval		Cut-off	Sensitivity	Specificity	PPV	NPV
	AUC	Std. error	p	Lower bound	Upper bound	Cut-off	Sensitivity	Specificity	PPV	NPV
CDI	0.998	0.002	< 0.001	0.994	1.000	> 18.5	(100.00)	(97.37)	(97.67)	(100.00)
MDA	0.832	0.049	< 0.001	0.735	0.928	> 0.285	(92.86)	(68.42)	(76.47)	(89.66)
SOD	0.930	0.029	< 0.001	0.872	0.987	< 17.66	(95.24)	(78.95)	(83.33)	(93.75)
TAS	0.769	0.054	< 0.001	0.664	0.875	< 0.635	(59.52)	(89.47)	(86.21)	(66.67)
TOS	0.921	0.029	< 0.001	0.863	0.978	> 8.235	(83.33)	(86.84)	(87.50)	(82.50)
OSI	0.958	0.019	< 0.001	0.920	0.995	> 1.30	(80.95)	(100.00)	(100.00)	(82.61)

Bold indicates p-value ≤ 0.05 is statistically significant
ROC analysis
CDI children depression inventory, MDA malondialdehyde, SOD superoxide dismutase, TAS total antioxidant status, TOS total oxidant status, OSI oxidative stress index, PPV positive predictive value, NPV negative predictive value, AUC area under curve