Effect of Letrozole on hippocampal Let-7 microRNAs and their correlation with working memory and phosphorylated Tau protein in an Alzheimer's disease-like rat model

Table 4 LSD for Let-7b fold change among different studied groups

	CSF (n = 6)	LV (n = 6)	CSF-LV (n = 6)	STZ (n = 9)	Letrozole (n = 9)	STZ-L (n = 9)
Negative control (n = 6)	0.63 NS	0.63 NS	0.75 NS	0.56 NS	0.007**	0.003**
CSF (n = 6)		0.99 NS	0.06 NS	0.48 NS	0.005**	0.001**
LV (n = 6)			0.06 NS	0.56 NS	0.01*	0.001**
CSF-LV (n = 6)				0.08 NS	0.002**	0.001**
STZ (n = 9)					0.004**	0.002**
Letrozole (n = 9)						0.63 NS

NS: Non significant (P > 0.05), *Significant (P < 0.05), **Highly significant (P < 0.01)