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Table 1 The effect of ESA on some of the neurophysiological findings and Hb levels in comparison to those of patients who did not receive ESA

From: Effect of Erythropoietin-stimulating agent on uremic neuropathy in hemodialysis patients: a single-center open-label prospective study

Nerve (n = 10)

0A

3A

p

Nerve (n = 8)

0B

3B

p

Median (n = 10)

   

Median (n = 8)

   

MNCV

49.51 ± 5.77

47.3 ± 5.6

0.094

MNCV

47.89 ± 7.53

47.05 ± 6.87

0.300

CMAP

5.97 ± 2.34

5.36 ± 2.15

0.469

CMAP

7.34 ± 4.72

6.28 ± 3.64

0.392

Ulnar (n = 10)

   

Ulnar (n = 8)

   

MNCV

44.87 ± 6.7

50.02 ± 5.55

0.016

MNCV

49.04 ± 4.95

48.01 ± 6.43

0.431

CMAP

5.97 ± 2.08

7.38 ± 2.08

0.067

CMAP

5.54 ± 1.86

5.8 ± 1.54

0.705

Peroneal (n = 8)*

   

Peroneal (n = 7)*

   

MNCV

40.91 ± 5.57

38.95 ± 4.96

0.188

MNCV

40.26 ± 7.89

39.16 ± 8.61

0.358

CMAP

2.38 ± 1.65

3.64 ± 2.8

0.134

CMAP

4.09 ± 2.49

3.28 ± 2.63

0.203

Tibial (n = 7)*

   

Tibial (n = 7)*

   

MNCV

41.31 ± 2.31

43.37 ± 4.64

0.126

MNCV

41.14 ± 8.92

37.96 ± 6.67

0.202

CMAP

3.97 ± 1.49

7.01 ± 5.28

0.262

CMAP

3.87 ± 1.49

3.70 ± 1.97

0.733

Median (n = 7)*

   

Median (n = 7)*

   

SNCV

46.51 ± 5.8

48.57 ± 5.5

0.263

SNCV

47.27 ± 9.23

45.97 ± 7.8

0.440

Ulnar (n = 7)*

   

Ulnar (n = 6)*

   

SNCV

45.3 ± 6.44

46.5 ± 12.6

0.740

SNCV

46.88 ± 12.0

46.52 ± 12.4

0.935

Radial (n = 7)*

   

Radial (n = 6)*

   

SNCV

48.2 ± 7.53

54.06 ± 4.6

0.009

SNCV

 

49.62 ± 10.36

0.527

Sural (n = 5)*

   

Sural (n = 4)*

   

SNCV

37.92 ± 6.7

24.56 ± 22.44

0.352

SNCV

45.73 ± 5.44

46.53 ± 3.69

0.763

Hb (g/dl)

7.92 ± 1.08

9.36 ± 0.8

0.000

 

8.33 ± 1.74

8.91 ± 1.09

0.139

  1. 0A baseline finding in patients received ESA, 3A finding after 3 months hemodialysis with ESA supplement, 0B baseline finding in patients who did not receive ESA, 3B finding after 3 months dialysis without ESA, MNCV motor nerve conduction velocity in m/s, CMAP compound motor action potential amplitude in mv, SNCV sensory nerve conduction velocity in m/s. *These drops in records are attributed to technical difficulties (ulcers, edema or AV fistula) in the tested side at one or the 2 sessions. Ulnar MNCV, Radial SNCV and Hb level showed statistically significant improvement in group A