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Table 2 Laboratory data and CSF pressure in IIH and control groups

From: Sex hormones, CSF and serum leptin in patients with idiopathic intracranial hypertension

  IIH group
(n = 38)
Control group
(n = 38)
P value
Serum leptin (ng/ml)
(mean ± SD)
68.2 ± 19.56 21.13 ± 14.5  < 0.001*
CSF leptin (ng/ml)
(mean ± SD)
3.64 ± 1.88 1.08 ± 0.64  < 0.001*
Serum estradiol (Pg/ml)
(mean ± SD)
196.15 ± 75.26 79.45 ± 45.15 0.005*
Serum testosterone (nmol/l)
(mean ± SD)
1.78 ± 0.53 0.93 ± 0.27  < 0.001*
Serum DHEAS (µmol/L)
(mean ± SD)
5.21 ± 1.84 4.97 ± 1.36 0.142
CSF pressure (cm H2O) (mean ± SD) 36.4 ± 7.3 17.6 ± 5.7  < 0.001*
  1. DHEAS dehydroepiandrosterone sulfate, IIH idiopathic intracranial hypertension, CSF cerebrospinal fluid, *: significant
  2. P value ≤ 0.05 was considered significant