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Table 2 Summary of cases reported in literature of GBS with vision loss due to Papilledema

From: Acute vision loss in Guillain–Barré syndrome: A case series and review of literature

 

Christina Doxaki et al. [11]

Kharbanda PS et al. [12]

Mathis S et al. [13]

Gross FJ et al. [14]

Hui-Jun Wen [15]

Our case

Variant of GBS

AIDP

AIDP

AIDP

AIDP

AIDP

AIDP

Age (year)/ sex

12/Female

35/Female

42/Male

27/Female

43/f

25/Female

Visual symptoms

Diminished vision

Diminished vision

Diminished vision

Transient visual obscuration

Blurred vision and Deterioration of near and distant vision and diplopia

Diminished vision

Headache

Present

Present

Absent

Not mentioned

Absent

Present

Signs of dysautonomia

Present

Present

Absent

Not mentioned

Absent

Present

BCVA

(RE and LE)

Reduced

Reduced

PL

PL

Reduced

Reduced

RE-20/20

LE- 20/20

Enlarged blind spot

RE-20/30

LE- 20/25

RE-6/60

LE-6/60

Papilledema

Present

Present

Present

Present

Present

Present

Signs of raised ICP on Neuroimaging

Not mentioned

Present

Not mentioned

Not mentioned

Normal

Present

CSF opening pressure

460 mm of CSF

420 mm of CSF

150 mm of CSF

310 mm of CSF

Not Mentioned

280 mm of CSF

ACD (CSF Proteins)

Present

(20 mg/dl)

Present (435 mg/dl)

Present (325 mg/dl)

Present (862 mg/l)

Present (78 mg/dl)

IVIG therapy

Given

Given

Given

Given

Given

Other treatment given

Acetazolamide

Corticosteroid

Acetazolamide

Corticosteroid

Not mentioned

Not mentioned

Intravenous

Dexamethasone and Mecobalamine

Mannitol

Acetazolamide

Corticosteroid

Reassessment of vision

After 2 months

Not mentioned

After 1 year

After ~ 6 months

3 weeks

After 1 month

BCVA after treatment

RE-6/6

LE-6/6

Not mentioned

RE-6/6

LE-6/6

RE-20/20

LE-20/20

Blind spot normal sized

RE-6/6

LE-6/6

RE-6/6

LE-6/6

  1. GBS Guillain–Barré syndrome, AIDP acute inflammatory demyelinating polyradiculoneuropathy, PL projection of light, mm millimetre, BCVA best corrected visual acuity, CSF cerebrospinal fluid, IV Ig intravenous immunoglobulin, RE right eye, LE left eye, ACD albumin cytological dissociation, ICP intracranial pressure, RE right eye, LE left