Fig. 4
From: An insight into Alzheimer’s disease and its on-setting novel genes
AD—Overall onset pathway. The above flowchart shows the details of the mechanism which occurs during the onset of AD. The formation of Aβ-42 in turn produces primary seeding aggregate which results in the deposition of peptide thus causing plaque formation. When this plaque didn’t get cleared by insufficient microglial activity result in the AD onset