Quality of life after ischaemic stroke—accent on patients with thrombolytic therapy

Tsalta-Mladenov, Mihael Emilov; Andonova, Silva Peteva

doi:10.1186/s41983-021-00418-w

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 3 Factors influencing the HR-QoL in thrombolized patients on the third-month post-stroke

From: Quality of life after ischaemic stroke—accent on patients with thrombolytic therapy

Factors		Adjusted R square	Beta	Std. error	P value	Confidence interval for Beta (95% CI)
Factors		Adjusted R square	Beta	Std. error	P value	Lower bound	Upper bound
Age	For each additional year	0.246	− 1.05	0.26	< 0.001	− 1.57	− 0.53
Age	> 65 years of age	0.156	− 21.95	7.04	0.003	− 36.13	− 7.76
Gender	Male	− 0.019	− 2.52	7.84	0.749	− 18.30	13.26
Gender	Female	− 0.019	2.52	7.84	0.749	− 13.26	18.30
Risk factors	Hypertension	0.024	− 26.89	18.36	0.150	− 63.85	10.07
	Atrial fibrillation	0.080	− 16.15	7.15	0.029	− 30.53	− 1.76
	Myocardial infarction	0.086	− 27.09	11.62	0.024	− 50.48	− 3.70
	Ischemic heart disease	0.055	− 14.44	7.45	0.059	− 29.45	0.57
	Heart failure	0.027	− 11.37	7.49	0.136	− 26.45	3.70
	Coronary artery disease	0.112	− 33.37	12.66	0.011	− 58.84	− 7.89
	Diabetes mellitus	− 0.004	− 9.55	10.54	0.370	− 30.77	11.66
	Dyslipidemia	− 0.20	2.38	7.95	0.766	− 13.628	18.39
Circulation	Anterior circulation	0.026	− 11.82	7.91	0.142	− 27.74	4.10
	• Left hemisphere	− 0.019	− 2.95	7.74	0.705	− 18.53	12.63
	• Right hemisphere	0.003	− 8.60	8.00	0.288	− 24.70	7.50
	Posterior circulation	0.026	11.82	7.91	0.142	− 4.10	27.74
Stroke severity (NIHSS)	NIHSS on admission (each additional point)	0.436	− 3.73	0.61	< 0.001	− 4.96	− 2.50
Stroke severity (NIHSS)	NIHSS on discharge (each additional point)	0.733	− 5.36	0.47	< 0.001	− 6.31	− 4.42
Computed Tomography (CT) on admission	Visible acute ischemic stroke	− 0.002	− 7.25	7.68	0.350	− 22.70	8.21
	Silent strokes	− 0.18	− 3.27	7.49	0.665	− 18.35	11.81
	Hyperdence middle brain artery	0.028	− 11.616	7.56	0.131	− 26.84	3.60
	ASPECTS (each additional point less)	− 0.020	− 0.305	1.068	0.776	− 2.46	1.84
Computed Tomography (CT) 24 h after thrombolysis	Formed ischemic zone	0.031	− 11.64	7.37	0.121	− 26.47	3.20
	Formed hemorrhagic zone	− 0.008	− 12.22	15.40	0.432	− 43.22	18.79
	Formed ischemic zone with hemorrhagic infarction	− 0.001	− 13.03	13.44	0.337	− 40.09	14.03
	No dynamics	0.144	18.82	7.09	0.011	4.55	33.09
Door-to-needle time	< 60 min	0.119	19.03	7.03	0.009	4.88	33.17
	60–120 min	0.016	− 10.07	7.61	0.192	− 25.39	5.25
	> 120 min	0.123	− 39.63	14.36	0.008	− 68.54	− 10.72
	For each additional minute	0.153	− 0.39	0.13	0.004	− 0.64	− 0.13

Bold values indicate P value is significant (less than 0.05)
NIHSS National Institutes of Health Stroke Scale, ASPECTS Alberta Stroke Programme Early CT Score

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