Gut microbiota in Parkinson’s disease patients: hospital-based study

Table 3 Correlation between copy number of different gut microbiota and Parkinson’s disease characteristics

Spearman correlation	Clostridium cluster IV	Firmicutes	Akkermansia	Bifidobacterium	Lactic acid bacteria
Duration of illness (years)
Rho-value	0.064	− 0.042	0.204	− 0.414	− 0.054
P-value	0.704	0.793	0.214	0.012*	0.742
UPDRS score
Rho-value	0.103	− 0.092	0.286	− 0.172	− 0.037
P-value	0.538	0.567	0.078	0.315	0.821
Self-assessment score
Rho-value	0.088	0.033	0.074	− 0.031	− 0.032
P-value	0.601	0.836	0.655	0.860	0.848
NMS of GIT score
Rho-value	− 0.055	0.038	0.100	− 143	− 0.101
P-value	0.742	0.814	0.543	0.405	0.542
Predominant type Tremors versus akinetic versus mixed)
Rho-value	− 0.198	0.241	− 0.261	0.160	0.130
P-value	0.234	0.129	0.108	0.352	0.431
Hoehn and Yahr stages (stage I, II, III, IV)
Rho-value	0.120	− 0.158	0.308	− 0.022	0.054
P-value	0.473	0.323	0.056	0.898	0.745

PD Parkinson’s disease, UPDRS score Unified Parkinson’s Disease Rating Score, NMS of GIT score; Non-motor symptoms of gastrointestinal tract score
*Correlation is significant P < 0.05 level (2-tailed)