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Table 4 The characteristics of the included systematic reviews regarding Guillen-Barre syndrome in COVID-19 infection

From: Neurological manifestations of COVID-19 infection: an umbrella review

Authors

Origin

Type

Quality

Number of included studies

Types of included studies

Assessing the quality of included studies

Searched databases

Main results

1. Carrillo-Larco et al. 2020 [64]

Europe

Systematic review

Critically low

8

Case series, case report

None

Embase, Scopus, Web of Science, Global Health, Medline, MedRvix

Basic evidence suggests that GBS1 occurs after COVID-19 onset

2. Gittermann et al. 2020 [68]

Chile

Systematic review

Low

24

Case series, case report

NHLBI2 tool

Pubmed, Cochrane Library, Science Direct, Medline, WHO search tool

There seem to be a strong association between the GBS and Covid-19 which differs in presentations, including the severity of the GBS manifestations

3. Uncini et al. 2020 [65]

Europe

Systematic review

Critically low

33

Case series, case report

None

Pubmed

Classical GBS is presented in Covid-19 patients

4. Hasan et al. 2020 [67]

Bangladesh

Systematic review + meta-analysis

Low

45

Case series, case report, cross sectional

JBI3 tool

Pubmed, Web of Science, Cochrane Library, Web of Science

An association exists between classic GBS and Covid-19. These manifestations are responsive to GBS standard treatments

5. Abu-Rumeileh et al. 2020 [66]

Germany

Systematic review

Critically low

52

Case series, case report, reviews with case reports, reviews, letters, original article, point of view, and brief report

None

Pubmed, Google Scholar

COVID-19-associated GBS seems to share most features of classic post-infectious GBS with possibly the same immune-mediated pathogenetic mechanisms

  1. 1. GBS: Guillain-Barré Syndrome; 2. NHLBI: National Heart, Lung, and Blood Institute; 3. JBI: Joanna Briggs Institute