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Table 4 The characteristics of the included systematic reviews regarding Guillen-Barre syndrome in COVID-19 infection

From: Neurological manifestations of COVID-19 infection: an umbrella review

Authors Origin Type Quality Number of included studies Types of included studies Assessing the quality of included studies Searched databases Main results
1. Carrillo-Larco et al. 2020 [64] Europe Systematic review Critically low 8 Case series, case report None Embase, Scopus, Web of Science, Global Health, Medline, MedRvix Basic evidence suggests that GBS1 occurs after COVID-19 onset
2. Gittermann et al. 2020 [68] Chile Systematic review Low 24 Case series, case report NHLBI2 tool Pubmed, Cochrane Library, Science Direct, Medline, WHO search tool There seem to be a strong association between the GBS and Covid-19 which differs in presentations, including the severity of the GBS manifestations
3. Uncini et al. 2020 [65] Europe Systematic review Critically low 33 Case series, case report None Pubmed Classical GBS is presented in Covid-19 patients
4. Hasan et al. 2020 [67] Bangladesh Systematic review + meta-analysis Low 45 Case series, case report, cross sectional JBI3 tool Pubmed, Web of Science, Cochrane Library, Web of Science An association exists between classic GBS and Covid-19. These manifestations are responsive to GBS standard treatments
5. Abu-Rumeileh et al. 2020 [66] Germany Systematic review Critically low 52 Case series, case report, reviews with case reports, reviews, letters, original article, point of view, and brief report None Pubmed, Google Scholar COVID-19-associated GBS seems to share most features of classic post-infectious GBS with possibly the same immune-mediated pathogenetic mechanisms
  1. 1. GBS: Guillain-Barré Syndrome; 2. NHLBI: National Heart, Lung, and Blood Institute; 3. JBI: Joanna Briggs Institute