From: Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study
Variables | Drug-naïve patients (n = 28) | Drug-treated patients (n = 29) | P |
---|---|---|---|
Age of onset (years) | |||
Mean ± SD | 21.1 ± 3.5 | 20.5 ± 2.7 | 0.5 |
Family history | |||
Positive | 18 (64.3%) | 21 (72.4%) | 0.5 |
Negative | 10 (35.7%) | 8 (27.6%) | |
Disease duration (years) | |||
Mean ± SD | 10.3 ± 3.5 | 13.1 ± 7.3 | 0.8 |
Duration of the current episode (days) | |||
Mean ± SD | 14.0 ± 3.1 | 15.4 ± 4.1 | 0.2 |
Number of previous episodes | |||
Median (range) | 5 (3 – 9) | 5 (3 – 11) | 0.5 |
Depression severity | |||
Mild | 6 (21.4%) | 19 (65.5%) | < 0.001 |
Moderate | 6 (21.4%) | 9 (31.0%) | (HS) |
Severe | 16 (57.1%) | 1 (3.4%) | |
Suicidal ideation | |||
BSS < 24 | 12 (42.9%) | 28 (96.6%) | < 0.001 |
BSS ≥24 | 16 (57.1%) | 1 (3.4%) | (HS) |