Table 4 Disease-related factors of SLE patients and their association with NPSLE
Factor | Total n = 100 | NPSLE n (%) | Non-NPSLE n (%) | p value |
|---|---|---|---|---|
Disease duration | ||||
Up to 2 years | 43 | 19 (34.5%) | 24 (53.3%) | 0.158 |
2–5 years | 39 | 24 (43.6%) | 15 (33.3%) | |
More than 5 years | 18 | 12 (21.8%) | 6 (13.3%) | |
Raynaud’s phenomenon | ||||
Present | 64 | 41 (74.5%) | 23 (51.1%) | 0.015 |
Absent | 36 | 14 (25.5%) | 22 (48.9%) | |
Comorbid conditions | ||||
DM | 1 | 0 | 1 (2.2%) | 0.088 |
HTN | 17 | 13 (23.6%) | 4 (8.9%) | |
Absent | 82 | 42 (76.3%) | 40 (88.9%) | |
Kidney involvement | ||||
Present | 29 | 24 (43.6%) | 5 (11.1%) | < 0.001 |
Absent | 71 | 31 (56.4%) | 40 (88.9%) | |
SLEDAI score at diagnosis | ||||
Low activity (< 10) | 81 | 36 (65.4%) | 45 (100%) | < 0.001 |
High activity (> 10) | 19 | 19 (34.6%) | 0 | |
Time of NPSLE development | ||||
Before starting treatment | 39 | 39 (70.9%) | 0 | < 0.001 |
After starting treatment | 16 | 16 (29.1%) | 0 | |