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Table 4 Disease-related factors of SLE patients and their association with NPSLE

From: Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Factor Total
n = 100
NPSLE
n (%)
Non-NPSLE
n (%)
p value
Disease duration
 Up to 2 years 43 19 (34.5%) 24 (53.3%) 0.158
 2–5 years 39 24 (43.6%) 15 (33.3%)
 More than 5 years 18 12 (21.8%) 6 (13.3%)
Raynaud’s phenomenon
 Present 64 41 (74.5%) 23 (51.1%) 0.015
 Absent 36 14 (25.5%) 22 (48.9%)
Comorbid conditions     
 DM 1 0 1 (2.2%) 0.088
 HTN 17 13 (23.6%) 4 (8.9%)
 Absent 82 42 (76.3%) 40 (88.9%)
Kidney involvement
 Present 29 24 (43.6%) 5 (11.1%) < 0.001
 Absent 71 31 (56.4%) 40 (88.9%)
SLEDAI score at diagnosis
 Low activity (< 10) 81 36 (65.4%) 45 (100%) < 0.001
 High activity (> 10) 19 19 (34.6%) 0
Time of NPSLE development
 Before starting treatment 39 39 (70.9%) 0 < 0.001
 After starting treatment 16 16 (29.1%) 0
  1. p value less than 0.05 is considered statistically significant; NPSLE neuropsychiatric systemic lupus erythematosus, Non- NPSLE patients without neuropsychiatric manifestations of systemic lupus erythematosus, SLE systemic lupus erythematosus, DM diabetes mellitus, HTN hypertension, SLEDAI the SLE disease activity index score