Clinical predictors to cognitive impairment in multiple sclerosis patients

Table 7 Correlation between clinical parameters and scores of cognitive scales in MS patients

	Age		EDSS		Attacks/year		Duration of illness
	r	P	r	P	r	P	r	P
ACE attention	− 0.08	0.59	− 0.45	0.002*	− 0.38	0.009*	− 0.236	0.119
ACE memory	− 0.23	0.12	− 0.64	< 0.001*	− 0.46	0.001*	− 0.58	< 0.001**
ACE language	− 0.23	0.11	− 0.81	< 0.001*	− 0.49	0.001*	− 0.47	0.001*
ACE fluency	− 0.22	0.14	− 0.33	0.027*	− 0.08	0.600	− 0.22	0.135
ACE visuospatial	− 0.06	0.66	− 0.27	0.065	0.00	0.988	− 0.16	0.270
ACE total	− 0.299	0.046	− 0.843	< 0.001*	− 0.500	< 0.001*	− 0.55	< 0.001**
PASAT 3	− 0.207	0.173	− 0.373	0.012*	− 0.268	0.075	− 0.21	0.165
Trail making type B	− 0.041	0.787	0.293	0.051	0.111	0.467	0.237	0.116

*Statistically significant
**Highly significant
ACE Addenbrooke’s cognitive examination III, PASAT 3 Paced auditory serial addition test, EDSS Expanded Disability Status Scale
P value is significant if ≤ 0.050