Skip to main content

Table 4 Impact of patient sex, route of chemotherapy, associated comorbidities, and remission status on the score of each component of cognitive functions

From: Chemotherapy-induced cognitive impairment in hematological malignancies

Variables Executive Naming Attention Language Abstraction Delayed recall Orientation Total score
Sex Male 3.54 ± 0.99 3.00 ± 0.00 3.77 ± 0.90 2.61 ± 0.63 1.08 ± 0.51 4.28 ± 0.95 5.85 ± 0.47 24.16 ± 3.70
female 3.52 ± 0.97 2.88 ± 0.42 3.62 ± 0.68 2.49 ± 0.75 1.07 ± 0.64 4.09 ± 1.16 5.75 ± 0.70 23.45 ± 4.47
t test t 0.10 2.64 1.05 1.10 0.07 1.09 1.04 1.04
p value 0.91 0.009 0.29 0.27 0.94 0.27 0.30 0.29
Route of CT Parenteral 3.44 ± 0.95 2.95 ± 0.27 3.69 ± 0.84 2.54 ± 0.69 1.04 ± 0.55 4.17 ± 1.06 5.80 ± 0.59 23.65 ± 4.07
Oral 4.40 ± 0.50 3.00 ± 0.00 3.93 ± 0.79 2.86 ± 0.35 1.40 ± 0.50 4.66 ± 0.48 6.00 ± 0.00 26.26 ± 2.08
t test t 3.73 0.63 1.04 1.77 2.36 1.77 1.29 2.44
p value < 0.001 0.52 0.29 0.07 0.02 0.07 0.19 0.01
Comorbidities Yes 3.13 ± 0.83 2.95 ± 0.20 3.39 ± 0.80 2.32 ± 0.66 0.80 ± 0.50 3.73 ± 1.06 5.69 ± 0.66 22.04 ± 3.81
No 3.72 ± 0.99 2.96 ± 0.27 3.86 ± 0.81 2.68 ± 0.65 1.20 ± 0.54 4.43 ± 0.95 5.87 ± 0.51 24.74 ± 3.80
t test t 3.53 0.11 3.30 3.04 4.21 3.96 1.79 3.99
p value 0.001 0.91 0.001 0.003 < 0.001 < 0.001 0.07 < 0.001
Remission status Remission 3.66 ± 0.91 3.00 ± 0.00 3.81 ± 0.75 2.68 ± 0.58 1.10 ± 0.39 4.42 ± 0.84 5.92 ± 0.36 24.61 ± 2.97
Not 3.27 ± 1.07 2.87 ± 0.44 3.51 ± 0.97 2.34 ± 0.81 1.02 ± 0.82 3.76 ± 1.25 5.59 ± 0.82 22.38 ± 5.35
t test t 2.25 2.90 2.09 2.90 0.86 3.78 3.37 3.26
p value 0.02 0.004 0.03 0.004 0.38 < 0.001 0.001 0.001