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Table 4 Impact of patient sex, route of chemotherapy, associated comorbidities, and remission status on the score of each component of cognitive functions

From: Chemotherapy-induced cognitive impairment in hematological malignancies

Variables

Executive

Naming

Attention

Language

Abstraction

Delayed recall

Orientation

Total score

Sex

Male

3.54 ± 0.99

3.00 ± 0.00

3.77 ± 0.90

2.61 ± 0.63

1.08 ± 0.51

4.28 ± 0.95

5.85 ± 0.47

24.16 ± 3.70

female

3.52 ± 0.97

2.88 ± 0.42

3.62 ± 0.68

2.49 ± 0.75

1.07 ± 0.64

4.09 ± 1.16

5.75 ± 0.70

23.45 ± 4.47

t test

t

0.10

2.64

1.05

1.10

0.07

1.09

1.04

1.04

p value

0.91

0.009

0.29

0.27

0.94

0.27

0.30

0.29

Route of CT

Parenteral

3.44 ± 0.95

2.95 ± 0.27

3.69 ± 0.84

2.54 ± 0.69

1.04 ± 0.55

4.17 ± 1.06

5.80 ± 0.59

23.65 ± 4.07

Oral

4.40 ± 0.50

3.00 ± 0.00

3.93 ± 0.79

2.86 ± 0.35

1.40 ± 0.50

4.66 ± 0.48

6.00 ± 0.00

26.26 ± 2.08

t test

t

3.73

0.63

1.04

1.77

2.36

1.77

1.29

2.44

p value

< 0.001

0.52

0.29

0.07

0.02

0.07

0.19

0.01

Comorbidities

Yes

3.13 ± 0.83

2.95 ± 0.20

3.39 ± 0.80

2.32 ± 0.66

0.80 ± 0.50

3.73 ± 1.06

5.69 ± 0.66

22.04 ± 3.81

No

3.72 ± 0.99

2.96 ± 0.27

3.86 ± 0.81

2.68 ± 0.65

1.20 ± 0.54

4.43 ± 0.95

5.87 ± 0.51

24.74 ± 3.80

t test

t

3.53

0.11

3.30

3.04

4.21

3.96

1.79

3.99

p value

0.001

0.91

0.001

0.003

< 0.001

< 0.001

0.07

< 0.001

Remission status

Remission

3.66 ± 0.91

3.00 ± 0.00

3.81 ± 0.75

2.68 ± 0.58

1.10 ± 0.39

4.42 ± 0.84

5.92 ± 0.36

24.61 ± 2.97

Not

3.27 ± 1.07

2.87 ± 0.44

3.51 ± 0.97

2.34 ± 0.81

1.02 ± 0.82

3.76 ± 1.25

5.59 ± 0.82

22.38 ± 5.35

t test

t

2.25

2.90

2.09

2.90

0.86

3.78

3.37

3.26

p value

0.02

0.004

0.03

0.004

0.38

< 0.001

0.001

0.001