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Table 1 Socio-demographic and clinical characteristics of MS patients according to their medication adherence (n = 598)

From: Treatment satisfaction and adherence to medications among multiple sclerosis patients in Saudi Arabia

Characteristics Total (n = 598) Adherent (n = 58, 9.7%) Non-adherent (n = 548, 90.3%) p value
Region 0.096a
 Southern 170 (28.4%) 20 (11.8%) 150 (88.2%)
 Middle 150 (25.1%) 20 (13.3%) 130 (86.7%)
 East 114 (19.1%) 8 (7.0%) 106 (93.0%)
 North 28 (4.7%) 0.0 28 (100.0%)
 West 136 (22.7%) 10 (7.4%) 126 (92.6%)
Gender 0.720a
 Male 214 (35.8%) 22 (10.3%) 192 (89.7%)
 Female 384 (64.2%) 36 (9.4%) 348 (90.6%)
Age in years, mean ± SD (range) 32.4 ± 8.5 (15–60) 33.5 ± 9.9 (15–56) 32.3 ± 8.3 (15–60) 0.323b
Marital status 0.597a
 Single 250 (41.8%) 24 (9.6%) 226 (90.4%)
 Married 310 (51.8%) 34 (11.0%) 276 (89.0%)
 Divorced 36 (6.0%) 0.0 36 (100.0%)
 Widower 2 (0.4%) 0.0 2 (100.0%)
Educational level < 0.001a
 Illiterate 4 (0.7%) 2 (50.0%) 2 (50.0%)
 Primary 12 (2.0%) 2 (16.7%) 10 (83.3%)
 Intermediate 28 (4.7%) 12 (42.9%) 16 (57.1%)
 Secondary 140 (23.4%) 4 (2.9%) 136 (97.1%)
 University 414 (69.2%) 38 (9.2%) 376 (90.8%)
Age at disease onset mean ± SD (range) 25.9 ± 7.9 (13–56) 27.3 ± 10.4 (14–51) 25.7 ± 7.6 (13–56) 0.136
Disease duration in years (mean ± SD) 6.6 ± 4.8 6.1 ± 4.5 6.6 ± 4.8 0.476b
No. of hospital admissions, mean ± SD 1.4 ± 1.7 1.1 ± 1.4 1.4 ± 1.7 0.139b
No. of attacks during last 2 years, mean ± SD (range) 1.4 ± 1.9 (0–14) 1.5 ± 1.0 (0–4) 1.9 ± 2.0 (0–14) 0.118b
Currently used disease-modifying therapiesc 0.032a
 Interferon beta-1b (SC) 144 (24.1) 14 (9.7) 130 (90.3)
 Interferon beta-1a (SC) 112 (18.7) 8 (7.1) 104 (92.9)
 Interferon beta-1a (IM) 100 (16.7) 12 (12.0) 88 (88.0)
 Fingolimod (PO) 104 (17.4) 18 (17.3) 86 (82.7)
 Others 90 (15.4) 4 (4.4) 86 (95.6)
PDDS (mean ± SD) 2.8 ± 1.9 3.1 ± 2.3 2.8 ± 2.00 0.219b
  1. aχ2 test
  2. bMann-Whitney test
  3. c48 cases were not using any medication