Neuro-ophthalmological biomarkers of visual outcome in newly diagnosed idiopathic intracranial hypertension

Table 2 Follow-up neuro-ophthalmological assessments for progressive IIH patients who needed lumpo-peritoneal shunts (group II)

		Baseline	2-week visit	Post-operative	ANOVA
		Baseline	2-week visit	Post-operative	f value	p value
Papilledema grade	Right	2.44 ± 0.73	2.89 ± 0.78	2.16 ± 0.53	1.0309	0.372
Papilledema grade	Left	2.41 ± 0.76	3.01 ± 0.72	2.09 ± 0.61	1.0289	0.301
MD–VFE	Right (decibel)	− 3.92 ± 0.44	− 6.23 ± 0.24	− 4.11 ± 0.37	94.360	0.0001*
MD–VFE	Left (decibel)	− 3.97 ± 0.48	− 6.39 ± 0.29	− 4.12 ± 0.46	114.402	0.0001*
ONSD	Right (mm)	7.81 ± 0.62	8.17 ± 0.63	4.91 ± 0.59	0.128	0.88
ONSD	Left (mm)	7.82 ± 0.59	7.96 ± 0.67	4.87 ± 0.51	0.825	0.45
OCT-RNFL	Right average (μm)	288.7 ± 18.25	317.81 ± 8.53	311.13 ± 15.41	9.759	0.0008*
OCT-RNFL	Left average (μm)	289.19 ± 18.73	316.34 ± 9.71	312.43 ± 15.53	8.475	0.0016*
VEP	Right P100 latency (ms)	127.3 ± 7.5	126.4 ± 6.5	126.8 ± 5.7	0.054	0.95
VEP	Left P 100 latency (ms)	127.7 ± 7.2	127.3 ± 6.5	125.8 ± 5.6	0.21	0.81

*: significant; MD–VFE mean deviation of visual field examination, OCT–RNFL optical coherence tomography–retinal nerve fiber layer, ONSD optic nerve sheath diameter, VEP visual evoked potential